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Research volume by year across topics

How much research each topic drew per year, counting only studies whose primary subject is that topic rather than papers that mention it in passing.

Most studied compounds

3,234 studies whose primary subject is ketamine since 2002

Studies about ketamine per year, 2002 to 2026, peaking at 782 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 400 800 2005 2010 2015 2020 2025
2026 is partial
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Studies about ketamine per year, 2002 to 2026, peaking at 782 in 2025
Year Studies
2002 2
2003 2
2004 3
2005 8
2006 3
2007 5
2008 9
2009 11
2010 15
2011 37
2012 16
2013 16
2014 37
2015 28
2016 39
2017 33
2018 59
2019 101
2020 144
2021 167
2022 233
2023 340
2024 517
2025 782
2026 627

2,709 studies whose primary subject is psilocybin since 2002

Studies about psilocybin per year, 2002 to 2026, peaking at 539 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 300 600 2005 2010 2015 2020 2025
2026 is partial
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Studies about psilocybin per year, 2002 to 2026, peaking at 539 in 2025
Year Studies
2002 11
2003 7
2004 6
2005 10
2006 15
2007 6
2008 6
2009 10
2010 15
2011 10
2012 24
2013 22
2014 19
2015 30
2016 40
2017 42
2018 62
2019 60
2020 123
2021 177
2022 275
2023 372
2024 381
2025 539
2026 447

1,627 studies whose primary subject is MDMA since 2002

Studies about MDMA per year, 2002 to 2026, peaking at 142 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about MDMA per year, 2002 to 2026, peaking at 142 in 2025
Year Studies
2002 31
2003 29
2004 47
2005 32
2006 61
2007 50
2008 50
2009 52
2010 80
2011 102
2012 38
2013 29
2014 41
2015 21
2016 32
2017 41
2018 37
2019 65
2020 62
2021 68
2022 117
2023 125
2024 137
2025 142
2026 138

1,006 studies whose primary subject is ayahuasca since 2002

Studies about ayahuasca per year, 2002 to 2026, peaking at 109 in 2023 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about ayahuasca per year, 2002 to 2026, peaking at 109 in 2023
Year Studies
2002 7
2003 9
2004 7
2005 19
2006 7
2007 5
2008 13
2009 16
2010 11
2011 25
2012 23
2013 23
2014 28
2015 27
2016 47
2017 35
2018 52
2019 42
2020 67
2021 67
2022 94
2023 109
2024 94
2025 106
2026 73

920 studies whose primary subject is cannabis since 2002

Studies about cannabis per year, 2002 to 2026, peaking at 148 in 2026 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about cannabis per year, 2002 to 2026, peaking at 148 in 2026
Year Studies
2002 5
2003 6
2004 13
2005 14
2006 18
2007 16
2008 19
2009 26
2010 25
2011 19
2012 20
2013 12
2014 11
2015 17
2016 16
2017 16
2018 19
2019 46
2020 50
2021 53
2022 67
2023 70
2024 90
2025 124
2026 148

LSD

869 studies whose primary subject is LSD since 2002

Studies about LSD per year, 2002 to 2026, peaking at 118 in 2023 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about LSD per year, 2002 to 2026, peaking at 118 in 2023
Year Studies
2002 9
2003 6
2004 4
2005 11
2006 6
2007 8
2008 11
2009 12
2010 13
2011 4
2012 11
2013 13
2014 10
2015 13
2016 33
2017 37
2018 26
2019 43
2020 50
2021 54
2022 82
2023 118
2024 91
2025 117
2026 87

Every topic

Studies per year, by topic. The year columns cover the last 10 years; the total covers everything tracked, up to 25 years back.

Studies per year for every research topic, with the total across every tracked year.
Topic 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 All years
Compounds 13
Ketamine 33 59 101 144 167 233 340 517 782 627 3,234
Psilocybin 42 62 60 123 177 275 372 381 539 447 2,709
MDMA 41 37 65 62 68 117 125 137 142 138 1,627
Ayahuasca 35 52 42 67 67 94 109 94 106 73 1,006
Cannabis 16 19 46 50 53 67 70 90 124 148 920
LSD 37 26 43 50 54 82 118 91 117 87 869
Esketamine 1 6 11 29 19 47 102 136 245 233 836
DMT 10 18 17 21 15 34 56 60 106 91 500
Ibogaine 10 21 11 12 18 14 24 24 32 33 293
5-MeO-DMT 5 9 12 13 10 13 28 33 57 46 288
Mescaline 9 9 15 12 13 26 35 24 24 15 261
Salvia divinorum 7 6 8 9 4 8 11 7 5 4 224
CBD 5 2 9 8 12 17 16 20 16 15 144
Conditions 5
Depression 41 55 89 140 198 255 399 511 761 648 3,308
Anxiety 47 55 70 117 140 164 207 262 404 473 2,154
Addiction 25 31 34 34 55 73 87 116 159 136 888
PTSD 16 23 23 30 48 72 66 97 119 102 662
End-of-life distress 1 1 5 2 5 9 11 16 33 35 122
Practices 4
Meditation 180 215 319 394 394 457 637 978 1,757 1,897 8,628
Psychedelic-assisted therapy 12 24 18 35 55 81 143 200 231 149 970
Microdosing 2 4 15 16 15 26 25 46 51 47 286
Breathwork 2 3 1 5 3 14 15 27 30 46 158
Experiences 6
Dreaming 30 50 44 76 55 59 79 95 123 122 1,031
Near-death experience 12 19 19 18 16 15 28 30 35 49 376
Mystical experience 10 10 10 21 25 37 33 43 52 46 366
Lucid dreaming 6 19 12 32 23 29 33 34 46 54 360
Altered states of consciousness 11 15 26 19 8 27 23 41 42 47 325
Ego dissolution 2 1 1 5 10 10 9 9 15 14 79
Traditions & thought 6
Philosophy of mind 43 54 64 63 66 92 92 131 206 420 1,456
Buddhism 17 20 24 35 36 45 47 58 164 222 781
Mysticism 12 18 23 32 37 53 75 69 128 202 765
Shamanism 12 24 18 28 33 40 36 57 66 76 525
Tulpamancy 1 0 0 1 1 0 3 1 0 2 13
Chaos magick 0 0 0 0 0 0 1 1 0 0 5
Mechanisms 3
Serotonin 23 46 41 57 56 83 86 105 152 147 1,144
Default mode network 14 25 25 31 34 36 34 36 75 143 612
Neuroplasticity 7 9 11 13 25 18 38 59 121 114 449