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Research volume by year across topics

How much research each topic drew per year, counting only studies whose primary subject is that topic rather than papers that mention it in passing.

Most studied compounds

3,735 studies whose primary subject is ketamine since 2002

Studies about ketamine per year, 2002 to 2026, peaking at 780 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 400 800 2005 2010 2015 2020 2025
2026 is partial
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Studies about ketamine per year, 2002 to 2026, peaking at 780 in 2025
Year Studies
2002 5
2003 3
2004 3
2005 11
2006 6
2007 8
2008 18
2009 18
2010 22
2011 51
2012 23
2013 26
2014 50
2015 56
2016 93
2017 120
2018 189
2019 119
2020 157
2021 183
2022 259
2023 350
2024 518
2025 780
2026 667

2,727 studies whose primary subject is psilocybin since 2002

Studies about psilocybin per year, 2002 to 2026, peaking at 530 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 300 600 2005 2010 2015 2020 2025
2026 is partial
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Studies about psilocybin per year, 2002 to 2026, peaking at 530 in 2025
Year Studies
2002 11
2003 7
2004 6
2005 10
2006 15
2007 6
2008 6
2009 10
2010 15
2011 11
2012 24
2013 22
2014 20
2015 30
2016 41
2017 44
2018 63
2019 60
2020 123
2021 176
2022 277
2023 371
2024 378
2025 530
2026 471

2,004 studies whose primary subject is MDMA since 2002

Studies about MDMA per year, 2002 to 2026, peaking at 146 in 2026 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about MDMA per year, 2002 to 2026, peaking at 146 in 2026
Year Studies
2002 41
2003 35
2004 55
2005 37
2006 72
2007 62
2008 80
2009 75
2010 97
2011 125
2012 55
2013 41
2014 76
2015 43
2016 71
2017 85
2018 82
2019 71
2020 65
2021 73
2022 122
2023 123
2024 134
2025 138
2026 146

1,714 studies whose primary subject is cannabis since 2002

Studies about cannabis per year, 2002 to 2026, peaking at 181 in 2026 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about cannabis per year, 2002 to 2026, peaking at 181 in 2026
Year Studies
2002 15
2003 9
2004 27
2005 25
2006 32
2007 45
2008 47
2009 50
2010 62
2011 62
2012 52
2013 31
2014 45
2015 64
2016 56
2017 72
2018 117
2019 76
2020 80
2021 94
2022 115
2023 138
2024 93
2025 126
2026 181

1,036 studies whose primary subject is ayahuasca since 2002

Studies about ayahuasca per year, 2002 to 2026, peaking at 109 in 2023 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about ayahuasca per year, 2002 to 2026, peaking at 109 in 2023
Year Studies
2002 7
2003 9
2004 7
2005 20
2006 7
2007 5
2008 14
2009 16
2010 11
2011 25
2012 23
2013 24
2014 33
2015 27
2016 51
2017 36
2018 55
2019 42
2020 69
2021 67
2022 94
2023 109
2024 95
2025 108
2026 82

LSD

919 studies whose primary subject is LSD since 2002

Studies about LSD per year, 2002 to 2026, peaking at 118 in 2023 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about LSD per year, 2002 to 2026, peaking at 118 in 2023
Year Studies
2002 9
2003 6
2004 4
2005 11
2006 6
2007 10
2008 13
2009 12
2010 14
2011 6
2012 13
2013 13
2014 16
2015 17
2016 39
2017 44
2018 32
2019 45
2020 51
2021 56
2022 85
2023 118
2024 91
2025 118
2026 90

Every topic

Studies per year, by topic. The year columns cover the last 10 years; the total covers everything tracked, up to 25 years back.

Studies per year for every research topic, with the total across every tracked year.
Topic 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 All years
Compounds 13
Ketamine 120 189 119 157 183 259 350 518 780 667 3,735
Psilocybin 44 63 60 123 176 277 371 378 530 471 2,727
MDMA 85 82 71 65 73 122 123 134 138 146 2,004
Cannabis 72 117 76 80 94 115 138 93 126 181 1,714
Ayahuasca 36 55 42 69 67 94 109 95 108 82 1,036
LSD 44 32 45 51 56 85 118 91 118 90 919
Esketamine 4 16 11 29 20 50 99 136 244 243 865
DMT 12 19 17 21 15 33 56 60 102 88 502
Ibogaine 11 22 11 12 17 13 22 24 30 36 301
5-MeO-DMT 6 9 12 13 10 13 28 33 54 47 291
Salvia divinorum 10 7 8 9 4 8 10 7 5 4 272
Mescaline 10 9 15 12 13 27 35 24 24 13 263
CBD 12 15 10 9 15 20 24 20 16 21 204
Conditions 5
Depression 128 182 121 168 239 332 458 512 761 693 4,007
Anxiety 93 128 98 145 184 249 315 268 403 495 2,742
Addiction 41 48 38 37 58 86 107 114 156 140 1,009
PTSD 31 41 33 36 54 84 81 95 118 111 786
End-of-life distress 2 2 5 2 5 9 11 15 32 36 122
Practices 4
Meditation 529 714 471 556 611 902 1,283 997 1,756 2,004 11,997
Psychedelic-assisted therapy 12 27 18 34 55 83 140 192 219 150 952
Microdosing 9 7 16 21 21 27 28 47 50 50 334
Breathwork 6 9 4 6 5 16 15 27 30 52 187
Experiences 6
Dreaming 59 73 54 90 78 82 100 95 122 129 1,285
Mystical experience 10 14 12 24 28 38 40 43 52 48 400
Near-death experience 15 28 20 20 19 16 30 28 30 46 399
Lucid dreaming 11 25 12 33 23 31 34 34 43 54 375
Altered states of consciousness 13 17 29 20 13 32 23 42 43 50 360
Ego dissolution 2 1 1 5 10 10 9 9 16 13 79
Traditions & thought 6
Philosophy of mind 68 100 78 70 82 110 119 130 206 360 1,660
Buddhism 35 45 31 43 45 64 69 58 163 207 925
Mysticism 19 37 25 33 39 58 82 69 127 191 832
Shamanism 19 53 22 30 34 42 43 57 66 69 604
Tulpamancy 1 0 0 1 1 0 3 1 0 2 13
Chaos magick 0 0 0 0 0 0 0 1 0 0 4
Mechanisms 3
Serotonin 43 73 44 60 57 84 87 105 151 158 1,293
Default mode network 32 78 30 32 35 50 77 42 82 145 790
Neuroplasticity 17 19 13 15 32 24 43 59 120 116 515