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Research volume by year across topics

How much research each topic drew per year, counting only studies whose primary subject is that topic rather than papers that mention it in passing.

Most studied compounds

3,856 studies whose primary subject is ketamine since 2002

Studies about ketamine per year, 2002 to 2026, peaking at 780 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 400 800 2005 2010 2015 2020 2025
2026 is partial
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Studies about ketamine per year, 2002 to 2026, peaking at 780 in 2025
Year Studies
2002 5
2003 3
2004 3
2005 11
2006 7
2007 8
2008 18
2009 20
2010 23
2011 58
2012 26
2013 26
2014 50
2015 57
2016 96
2017 122
2018 206
2019 124
2020 157
2021 184
2022 261
2023 355
2024 518
2025 780
2026 738

2,758 studies whose primary subject is psilocybin since 2002

Studies about psilocybin per year, 2002 to 2026, peaking at 530 in 2025 Bar chart: one bar per year, taller where more studies were published that year. 0 300 600 2005 2010 2015 2020 2025
2026 is partial
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Studies about psilocybin per year, 2002 to 2026, peaking at 530 in 2025
Year Studies
2002 11
2003 7
2004 6
2005 10
2006 15
2007 6
2008 7
2009 10
2010 15
2011 11
2012 24
2013 22
2014 20
2015 31
2016 41
2017 44
2018 63
2019 60
2020 123
2021 177
2022 277
2023 375
2024 378
2025 530
2026 495

2,060 studies whose primary subject is MDMA since 2002

Studies about MDMA per year, 2002 to 2026, peaking at 158 in 2026 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about MDMA per year, 2002 to 2026, peaking at 158 in 2026
Year Studies
2002 41
2003 37
2004 55
2005 37
2006 73
2007 63
2008 81
2009 78
2010 99
2011 130
2012 60
2013 41
2014 78
2015 47
2016 73
2017 86
2018 92
2019 71
2020 66
2021 73
2022 122
2023 126
2024 134
2025 139
2026 158

1,887 studies whose primary subject is cannabis since 2002

Studies about cannabis per year, 2002 to 2026, peaking at 220 in 2026 Bar chart: one bar per year, taller where more studies were published that year. 0 150 300 2005 2010 2015 2020 2025
2026 is partial
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Studies about cannabis per year, 2002 to 2026, peaking at 220 in 2026
Year Studies
2002 15
2003 9
2004 27
2005 25
2006 33
2007 47
2008 48
2009 52
2010 64
2011 67
2012 52
2013 31
2014 49
2015 69
2016 65
2017 78
2018 130
2019 79
2020 92
2021 112
2022 133
2023 166
2024 98
2025 126
2026 220

1,057 studies whose primary subject is ayahuasca since 2002

Studies about ayahuasca per year, 2002 to 2026, peaking at 111 in 2023 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about ayahuasca per year, 2002 to 2026, peaking at 111 in 2023
Year Studies
2002 7
2003 9
2004 7
2005 20
2006 7
2007 5
2008 14
2009 16
2010 11
2011 25
2012 23
2013 24
2014 33
2015 27
2016 52
2017 39
2018 57
2019 42
2020 71
2021 67
2022 95
2023 111
2024 95
2025 108
2026 92

LSD

929 studies whose primary subject is LSD since 2002

Studies about LSD per year, 2002 to 2026, peaking at 120 in 2023 Bar chart: one bar per year, taller where more studies were published that year. 0 100 200 2005 2010 2015 2020 2025
2026 is partial
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Studies about LSD per year, 2002 to 2026, peaking at 120 in 2023
Year Studies
2002 9
2003 6
2004 4
2005 11
2006 6
2007 10
2008 14
2009 12
2010 14
2011 6
2012 13
2013 13
2014 16
2015 17
2016 39
2017 44
2018 33
2019 45
2020 52
2021 56
2022 85
2023 120
2024 91
2025 118
2026 95

Every topic

Studies per year, by topic. The year columns cover the last 10 years; the total covers everything tracked, up to 25 years back.

Studies per year for every research topic, with the total across every tracked year.
Topic 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 All years
Compounds 13
Ketamine 122 206 124 157 184 261 355 518 780 738 3,856
Psilocybin 44 63 60 123 177 277 375 378 530 495 2,758
MDMA 86 92 71 66 73 122 126 134 139 158 2,060
Cannabis 78 130 79 92 112 133 166 98 126 220 1,887
Ayahuasca 39 57 42 71 67 95 111 95 108 92 1,057
LSD 44 33 45 52 56 85 120 91 118 95 929
Esketamine 4 17 11 29 20 50 99 136 244 268 891
DMT 12 19 17 21 16 34 56 60 102 96 513
Ibogaine 11 22 11 12 17 14 22 24 30 38 306
5-MeO-DMT 6 9 12 13 10 13 28 33 54 50 294
Salvia divinorum 10 7 8 9 4 8 10 8 5 6 280
Mescaline 10 9 15 12 13 27 35 24 24 14 266
CBD 12 16 10 9 16 21 30 23 16 23 219
Conditions 5
Depression 130 206 124 169 247 344 466 512 761 761 4,156
Anxiety 94 143 104 146 193 257 328 269 403 536 2,847
Addiction 42 52 38 37 61 89 114 114 156 161 1,053
PTSD 34 53 33 37 58 87 87 95 118 123 831
End-of-life distress 3 3 5 2 5 9 11 15 32 37 126
Practices 4
Meditation 561 839 495 587 661 978 1,404 1,002 1,756 2,334 12,880
Psychedelic-assisted therapy 12 29 18 34 55 84 140 192 219 161 966
Microdosing 9 7 16 21 21 28 28 47 50 51 336
Breathwork 7 9 4 6 5 16 16 27 30 57 194
Experiences 6
Dreaming 60 81 55 92 79 84 107 95 122 150 1,338
Mystical experience 10 14 13 24 29 40 41 43 52 53 412
Near-death experience 15 30 20 20 19 16 30 28 30 47 407
Lucid dreaming 11 26 12 34 23 32 34 34 43 58 384
Altered states of consciousness 13 17 29 20 13 32 23 42 43 52 364
Ego dissolution 2 1 1 5 10 10 9 9 16 15 81
Traditions & thought 6
Philosophy of mind 77 121 79 73 85 116 139 130 208 408 1,803
Buddhism 39 54 31 44 50 68 74 58 163 229 991
Mysticism 19 39 25 33 41 60 86 69 127 201 858
Shamanism 19 62 22 30 35 42 47 57 66 81 633
Tulpamancy 1 0 0 1 1 0 3 1 0 3 14
Chaos magick 0 0 0 0 0 0 0 1 0 1 5
Mechanisms 3
Serotonin 44 73 45 62 59 86 91 105 151 168 1,324
Default mode network 32 82 33 32 35 51 79 42 82 149 817
Neuroplasticity 18 22 13 16 32 24 45 60 120 120 535