Hop and Medicinal Plants
December 28, 2022
Vanessa Eveline Vlaic, Andreea Ona
The therapeutic use of the substance psilocin produced by the fungi from the genus named Psilocybe has been an interesting but also controversial topic of discussion among researchers since the 1950s until now. These fungi can synthesize several alkaloids such as psilocybin, which has hallucinogenic properties, but also muscarine, which is a toxic substance that stimulates that part of the...
Case Reports in Psychiatry
December 15, 2022
Zeeshan Faruqui, Christopher Kim
Alcohol use disorder (AUD) is especially prevalent among individuals with major depressive disorder (MDD) and is associated with higher morbidity, mortality, disability, and risk for suicide. Intranasal esketamine has been documented to be a safe and effective option for treatment resistant MDD and received US FDA approval in 2019. However, the availability of esketamine is limited due to...
Frontiers in Psychology
December 5, 2022
Chunhui You, Yang Liu
As social media has become more imperative in daily life, people pay more attention to self-presentation and impression management on social media, and some have even become psychologically dependent. There is a large group of socially addicted users who continuously strive to improve their online self-presentation. Due to stress and burnout arising from social media addiction, people change...
Journal of Addiction & Addictive Disorders
December 2, 2022
Suchismita Ray
The opioid epidemic continues to be a growing public health concern in the United States, with Black mothers who have young children being a particularly vulnerable population. In this review, the authors first summarize the mental and physical health disparities faced by this population from the perspective of minority stress theory, considering the role of racial discrimination, gender...
Cureus
December 1, 2022
Kristen Strom, Ateaya Lima, Vahideh Tabarzadi
Growing in prevalence as a recreational drug of abuse across a broad scope of people, nitrous oxide (N2O) has proven to be a public health concern. Side effects of its abuse have a great degree of variation among people ranging from neurologic, psychiatric, and medical symptoms. We present a rare case of a 23-year-old female with a history of N2O abuse, who presented with symptoms of both...
Contemporary Clinical Trials
December 1, 2022
Kelley C O'Donnell, Sarah E. Mennenga, Lindsey T. Owens et al.
24 citations
Several lines of evidence suggest that classic psychedelics (5-HT2A receptor agonists or partial agonists) such as psilocybin might facilitate behavior change in individuals with substance use disorders. We conducted a multi-site, double-blind, randomized controlled trial (RCT) to assess the effects of psilocybin-assisted psychotherapy in alcohol-dependent volunteers. In addition to a...
OBM Integrative and Complementary Medicine
November 14, 2022
Nils Altner, Jasmin Friedrich
3 citations
In this study, we present the results of a 48-hour mindfulness-based and compassion-based training for teachers (N = 59). This study included 3,250 students in two years. We strengthened the resources of teachers and students for health, especially for preventing addiction. The didactic approach was based on the concepts of embodiment and resonance. We first trained teachers and then encouraged...
Addictive Behaviors Reports
November 11, 2022
Itamar José Félix-Junior, Ana Paula G Donate, Ana Regina Noto et al.
Inpatient treatment for Substance Use Disorder (SUD), such as Therapeutic Communities and Residential Treatment has been used to test the effect of Mindfulness-Based Interventions (MBI) over different outcomes. Although there is evidence of the effectiveness of MBIs, little is known about the particularities that the place may have in the outcomes. The main objective of this Systematic Review...
The Brown University Psychopharmacology Update
November 3, 2022
Two sessions of psilocybin‐assisted psychotherapy resulted in reduced heavy‐drinking days and other alcohol‐related problems relative to placebo plus psychotherapy in a randomized trial involving patients with alcohol use disorder (AUD). There were no serious adverse events associated with psilocybin administration, and no signs of psychotic disturbances. Study results were published online...
فصلنامه علمی و پژوهشی اعتیادپژوهی
November 1, 2022
Vida Khan, Saeed Imani, Omid Shokri et al.
مدل تاب ّي عل روابط يابي ذهن
British Journal of Clinical Pharmacology
November 1, 2022
Bruno Revol, Maryse Lapeyre-Mestre, Nathalie Fouilhé Sam-Lai et al.
Ketamine and dextromethorphan are widely abused psychoactive substances. Inhibition of N-methyl-d-aspartate receptors (NMDARs) results in neurobehavioural effects including hallucinations, "out of body" sensations and dissociative effects. However, little is known about a possible extended addictive class effect linked to pharmacologically-related amino-adamantane derivatives (e.g., amantadine...
Current Neuropharmacology
October 20, 2022
Alessio Mosca, Stefania Chiappini, Andrea Miuli et al.
30 citations
BACKGROUND: Ibogaine and noribogaine are psychedelic substances with dissociative properties naturally occurring in plants of the Apocynaceae family. Research has shown their efficacy in treating substance use disorders (SUD), particularly in opiate detoxification, but their efficacy and toxicity are still unclear. OBJECTIVE: This review aims to assess the anti-addictive role of ibogaine and...
Alcoholism & Drug Abuse Weekly
October 14, 2022
Alison Knopf
The beneficial effects of psilocybin‐assisted psychotherapy on alcohol use disorder (AUD) are significant, based on a study published in JAMA Psychiatry last month. In general, psychedelic medications have been a focus of research, but less is known about psilocybin, and it has been 40 years since the studies with lysergic acid diethylamide (LSD) provided double the remissions as comparison...
Biomolecules
October 12, 2022
Justin Matheson, Zoe Bourgault, Bernard Le Foll
Cannabidiol (CBD) is a non-intoxicating cannabinoid compound with diverse molecular targets and potential therapeutic effects, including effects relevant to the treatment of psychiatric disorders. In this scoping review, we sought to determine the extent to which sex and gender have been considered as potential moderators of the neuropsychiatric effects and pharmacokinetics of CBD. In this...
Vertex Revista Argentina de Psiquiatría
October 10, 2022
Federico Pavlovsky, Rafael Groisman, Ana Karina Hurtado et al.
Addictions are one of the most important health problems worldwide. Within these disorders, cannabis is one of the psychoactive substances with more burden of morbidity and mortality worldwide. The actual knowledge about the effectiveness of treatments for cannabis use disorders is unsatisfactory. This review aims to explore the evidence on cannabidiol for the treatment of cannabis use...
Health Psychology Research
October 6, 2022
Amber N. Edinoff, Natalie W. Wu, Bryce Bonin et al.
11 citations
Even as prescription opioid dispensing rates have begun to decrease, the use of illicit opioids such as heroin and fentanyl has increased. Thus, the end of the opioid epidemic is not in sight, and treating patients that are addicted to opioids remains of utmost importance. Currently, the primary pharmacotherapies used to treat opioid addiction over the long term are the opioid antagonist...
JAMA
October 4, 2022
Anita Slomski
6 citations
Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck...
The Journal of Nervous and Mental Disease
October 1, 2022
Andrew J Biedlingmaier, Timothy G Yovankin, Maju Mathew Koola et al.
There is evidence that mindfulness-based interventions are effective as stress-reduction techniques in people with various stressor-related disorders. Research also shows overall improvement in mental health well-being in practitioners of mindfulness. However, there is limited literature probing the potential negative impacts of mindfulness practice. Relapse is a major challenge in substance...
Journal of Forensic and Legal Medicine
October 1, 2022
Devendra Jadav, Rutwik Shedge, Vikas P Meshram et al.
Psychoactive substances have been used by humankind for recreational purposes since time immemorial. The psychoactive properties of these substances are known to alter the consciousness, mood, and perception of people taking them. While the use of alcohol, opioids, and cannabinoids for recreational purposes has been researched thoroughly, cases of using psychoactive fauna or animal body parts...
BMJ Open
October 1, 2022
Mathias Ebbesen Jensen, Dea Siggaard Stenbæk, Tobias Søgaard Juul et al.
21 citations
Introduction Alcohol use disorder is a difficult-to-treat psychiatric disorder and a major burden on public health. Existing treatment efficacy is moderate, and relapse rates are high. Preliminary findings suggest that psilocybin, a psychedelic compound, can safely and reliably occasion highly meaningful experiences that may spur a positive change in drinking behaviour when administered in a...