The International Journal of Neuropsychopharmacology
December 29, 2020
Mu-Hong Chen, Wan-Chen Chang, Wei-Chen Lin et al.
28 citations
Frontostriatal disconnectivity plays a crucial role in the pathophysiology of major depressive disorder. However, whether the baseline functional connectivity of the frontostriatal network could predict the treatment outcome of low-dose ketamine infusion remains unknown. In total, 48 patients with treatment-resistant depression were randomly divided into 3 treatment groups (a single-dose...
Appetite
December 26, 2020
Ti Hsu, Catherine A Forestell
Emotional eating is defined as the tendency to increase food consumption in order to modify negative emotional states. Theories on emotional eating attribute its cause to inadequate emotion regulation, specifically an inability to draw awareness to and accept distress. Mindfulness, or the ability to pay attention to and accept internal and external experiences, is thought to attenuate the...
Global Advances in Health and Medicine
December 23, 2020
Dawson Church, Peta Stapleton, Debbie Sabot
Background: A growing body of clinical research attests to the psychological and physiological benefits of meditation. EcoMeditation is a non-pharmacological therapeutic approach used to promote health and well-being, comprising four evidence-based techniques: The Quick Coherence Technique for regulating heart rate variability (HRV), Emotional Freedom Techniques (EFT), mindfulness, and...
HRB Open Research
December 16, 2020
Bronagh Gallagher, Meabh Foley, C. Slattery et al.
6 citations
Background: Depression is a common psychiatric disorder that has become the leading cause of disability worldwide. The standard medical care for depression over the past 50 years has focused on monoamine neurotransmitters. These treatments can take weeks to take effect, highlighting the need for novel treatment strategies. One such approach may be ketamine. Ketamine acts as an antagonist of the...
International Journal of Environmental Research and Public Health
December 14, 2020
Erica R Timko Olson, Margaret M Hansen, Amber L Vermeesch
Mindfulness and Shinrin-yoku (SY) translated as forest bathing, is potentially effective to alleviate mental health issues related to the COVID-19 pandemic and beyond. The purpose of this article is to provide a translational and pragmatic approach to understanding mindfulness in the context of SY and psychological wellbeing through a rapid review of the literature. The background of...
Journal of Psychiatric Research
December 11, 2020
Jiaqi Xiong, Orly Lipsitz, David C J Chen-Li et al.
122 citations
The efficacy of ketamine in reducing suicidal ideation (SI) has been previously reported. We aimed to evaluate acute anti-SI effects of single-dose ketamine in different formulations/routes of administration by pooling results from randomized controlled trials (RCTs). A systematic search was conducted on Cochrane, Embase, Medline, and PubMed from inception to July 1st, 2020. Studies were...
Brain Sciences
December 11, 2020
Jakub Słupski, Wiesław Jerzy Cubała, Natalia Górska et al.
7 citations
Changes in serum copper concentration are observed in patients with depressive symptoms. Unmet needs in contemporary antidepressant treatment have increased interest in non-monoaminergic antidepressants, such as ketamine, an anaesthetic drug that has demonstrated a rapid antidepressant effect in patients with treatment-resistant depression (TRD). The purpose of this study was to examine whether...
CNS Spectrums
December 10, 2020
Nelson B Rodrigues, Ashley N. Siegel, Orly Lipsitz et al.
17 citations
BACKGROUND: Patients unsuccessfully treated by neurostimulation may represent a highly intractable subgroup of depression. While the efficacy of intravenous (IV) ketamine has been established in patients with treatment-resistant depression (TRD), there is an interest to evaluate its effectiveness in a subpopulation with a history of neurostimulation. METHODS: This retrospective, posthoc...
Journal of Clinical Medicine
December 9, 2020
Marine Ambar Akkaoui, Michel Lejoyeux, Marie-Pia d'Ortho et al.
Chronic nightmares are very common in psychiatric disorders, affecting up to 70% of patients with personality or post-traumatic stress disorders. In other psychiatric disorders, the relationships with nightmares are poorly known. This review aimed to clarify the relationship between nightmares and both mood and psychotic disorders. We performed a systematic literature search using the PubMed,...
BMC sports science, medicine & rehabilitation
December 7, 2020
Hiromitsu Miyata, Daisuke Kobayashi, Akifumi Sonoda et al.
Background: Empirical data have suggested that mind-body practices that originated in Eastern traditions can cause desirable changes to psychological traits, the brain, somatic physiological functions, etc. Martial arts in Japan refer to the physical/mental practices that were developed based on historical combat techniques. Today, martial arts are considered activities that seek embodiment...
medRxiv Preprint Server
December 7, 2020
Vasileia Kotoula, Argyris Stringaris, Nuria Mackes et al.
9 citations
preprint
Ketamine as an antidepressant improves anhedonia, a pernicious symptom of depression as early as 2h post-infusion. The effects of ketamine on anhedonia are thought to be exerted via actions on reward-related brain areas—yet, these actions remain largely unknown. This study examines ketamine’s effects during the anticipation and receipt of an expected reward, after the psychotomimetic effects of...
CNS Spectrums
December 3, 2020
Orly Lipsitz, Roger S McIntyre, Nelson B Rodrigues et al.
25 citations
BACKGROUND: Higher body mass index (BMI) has been found to predict greater antidepressant response to intravenous (IV) ketamine treatment. We evaluated the association between BMI and response to repeat-dose IV ketamine in patients with treatment-resistant depression (TRD). METHODS: Adults (N = 230) with TRD received four infusions of IV ketamine at a community-based clinic. Changes in symptoms...
Clinical Gerontologist
December 2, 2020
Jenny Murfield, Wendy Moyle, Analise O'Donovan et al.
Objectives: This study explored the role of compassion and dispositional mindfulness in the psychological health of family carers of older adults and tested for potential mediating effects of emotion regulation difficulties and adaptive coping strategies. Methods: A sample of 141 family carers of adults aged 65 years or older with chronic conditions completed a cross-sectional survey between...
JMIR Mental Health
December 2, 2020
Paul Ritvo, F. Ahmad, Christo El Morr et al.
Background University students are experiencing higher levels of distress and mental health disorders than before. In addressing mental health needs, web-based interventions have shown increasing promise in overcoming geographic distances and high student-to-counselor ratios, leading to the potential for wider implementation. The Mindfulness Virtual Community (MVC) program, a web-based program,...
BMC Psychiatry
December 1, 2020
S. Chan, Wendy W. K. Chan, J. Chao et al.
Background The goal of this study was to investigate treatment outcome and related intervention processes of mindfulness-based cognitive therapy versus health qigong-based cognitive therapy versus waitlist control among individuals with mood disorders. Methods A total of 187 individuals with mood disorders were randomized and allocated into mindfulness-based cognitive therapy, health...
Integrative Medicine Research
December 1, 2020
Matthew J Leach, Heather Lorenzon, Sandy Nidich
Almost one in three women worldwide will be exposed to domestic and family violence some time in their life. This violence can contribute to physical, social, economic and psychological harm. Transcendental Meditation® (TM) may help to lessen the physical and emotional burden of domestic violence. The objective of this pilot, parallel-group, randomized controlled trial is to compare the...
Mindfulness
December 1, 2020
Aleksandra Eriksen Isham, Adriana Del Palacio-Gonzalez, Barbara Dritschel
Abstract Objectives Depression is associated with both emotion dysregulation upon retrieval of autobiographical memories and low trait mindfulness. The present study raised the question of whether these processes are related to each other and whether they may reflect a cognitive-affective vulnerability in individuals at risk of depression. The study examined emotion regulation in response to...
Drug and Therapeutics Bulletin
December 1, 2020
3 citations
Generic name: Esketamine hydrochloride Brand name: Spravato Formulation: 28mg in 0.2ml nasal spray solution Market Authorisation holder: Janssen-Cilag International NV Indication: Treatment resistant major depressive disorder in adults who have failed to respond to at least two different antidepressants during the current moderate to severe episode. To be used in combination with a selective...
Neuroscience & Biobehavioral Reviews
November 23, 2020
Hartej Gill, Barjot Gill, Nelson B Rodrigues et al.
92 citations
Replicated evidence has documented cognitive deficits in populations with treatment-resistant depression (TRD). Approximately 40% of patients with MDD present with impairment of one or more cognitive domains. As such, there is an unmet need to discover treatments that have pro-cognitive effects in TRD patients. Ketamine has demonstrated efficacy as a rapid-onset intervention for the treatment...
Complementary Therapies in Medicine
November 16, 2020
Holger C Bringmann, Nicole Bringmann, Michael Jeitler et al.
16 citations
BACKGROUND Integrative mental health care can be used to treat depression with a person-centered, lifestyle-modifying, and more salutogenic approach to mental health and human flourishing. In this article, we report on the feasibility and acceptability of a new mind-body program, Meditation Based Lifestyle Modification (MBLM), in outpatients with mild or moderate depression. METHODS This is a...