Introduction Cannabis use impairs cognitive performance in healthy subjects; several studies have shown improved cognitive outcomes in schizophrenic patients using cannabis. The aim of this study was to evaluate the effects of cannabis use on cognitive function in Moroccan patients with schizophrenia who were cannabis users. Method Two groups were recruited in a Moroccan University Psychiatric...
Highly potent cannabis concentrates are widely available and associated with affective disturbance and cannabis use disorder. Little is known about the effects of concentrated Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) and their relationship to long-term affect. We explored how baseline affective symptoms (anxiety and depression) relate to acute (i.e., immediate or short-term)...
Delta-9-tetrahydrocannabinol, a component of marijuana, interacts with cannabinoid receptors in brain involved in memory, cognition, and emotional control. However, marijuana use and schizophrenia development is a complicated and contentious topic. As a result, more investigation is needed to understand this relationship. Through the functional enrichment analysis, we report the...
Research SquareNovember 20, 2023Ottone Baccaredda Boy, Giuseppe Pierpaolo Merola, Andrea Patti et al.
preprint
Abstract the present paper describes the preliminary results of a study centered on the effect of salience alterations and cannabis use on the intensity of psychotic symptoms in adolescent and adult cohorts. The exploratory analysis focused on cross-sectional scores at psychometric questionnaires of 64 participants allocated to 4 different subgroups. A hierarchical pattern in the...
European PsychiatryNovember 17, 2023L. Fernandez Mayo, D. Baño Rodrigo, E. Barbero García et al.
Introduction While it is well known that there is an interaction between sleep disorders and substance abuse, it is certainly more complex than was previously thought. The effects on sleep depend on the substance used, but it has been shown that both during use and in withdrawal periods consumers have various sleep problems, and basically more fragmented sleep. We know that sleep problems must...
Introduction Recent studies reported very high cumulative risk for a patient who had cannabis-induced psychosis to be diagnosed with a schizophrenia spectrum disorder. Objectives We aim to compare sociodemographic and clinical characteristics, treatment and discharge plan in cannabis-induced first psychosis episode (CI-FEP) vs. multiple cannabis-induced psychotic episodes (CI-MEP) inpatients....
Abstract Background Trends in cannabis use suggest a global increase in the past decade. Current evidence associates cannabis use with an increased risk of psychosis. This association has prompted a growing research interest in the association between cannabis use and psychiatric disorders, especially psychotic disorders. This study aims to gain a better understanding of the effect of cannabis...
Cannabis and classic psychedelics are controlled substances with emerging evidence of efficacy in the treatment of a variety of psychiatric illnesses. Cannabis has largely not been regarded as having psychedelic effects in contemporary literature, despite many examples of historical use along with classic psychedelics to attain altered states of consciousness. Research into the “psychedelic”...
Medical cannabis (MC) is increasingly used for chronic pain, but it is unclear how it aids in pain management. Previous literature suggests that MC could holistically alter the pain experience instead of only targeting pain intensity. However, this hypothesis has not been previously systematically tested. A retrospective internet survey was used in a sample of Finnish chronic pain patients (40...
Research, Society and DevelopmentNovember 4, 2023João Marcelo Defanti Zonaro, Tiago Emanoel Melo Pereira, Renan Chaparro Rodrigues Alves Barbosa Coelho
Introdução: A Cannabis é a terceira substância psicoativa mais utilizada no mundo. Seu uso, além de outras comorbidades, tem impacto na saúde mental, com destaque para os quadros esquizofrênicos, uma vez que cerca de 26.6% desses pacientes sofrem do Transtorno pelo uso da Cannabis (TUC). O uso dessa droga é frequente em pacientes com desordens psicóticas, como a esquizofrenia e também parece...
Theoretical models of addictive behavior suggest that subjective effects serve as a mechanism through which substance use disorders develop. However, little is known about the subjective effects of simultaneous alcohol and cannabis use, particularly whether simultaneous use (a) heightens specific subjective effects or (b) is related to unique subjective effects relative to single-substance...
Cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid system. While cannabis use is quite prevalent in many individuals afflicted with psychiatric illnesses, there is considerable controversy as to whether cannabis may worsen these conditions or provide some form of therapeutic benefit. The...
Human factorsNovember 2023Sonia Ortiz-Peregrina, Oscar Oviedo-Trespalacios, Carolina Ortiz et al.
This study analyzed the self-regulation behaviors of drivers under the influence of cannabis and its relationship with road complexity and some driver traits, including visual deterioration. Cannabis is the illicit drug most often detected in drivers; its use results in significant negative effects in terms of visual function. Self-regulation behaviors involve the mechanisms used by drivers to...
Psychiatry ResearchNovember 1, 2023J. Groening, Emma Denton, Rimsha Parvaiz et al.
While the legal status and public perception of cannabis are currently changing in many countries, one of the important considerations from a public health viewpoint is its potential association with adverse health outcomes such as the development of psychosis. We conducted an umbrella review of systematic reviews and meta-analyses using the AMSTAR-2 to assess the quality of included reviews....
There is increased risk of psychosis associated with cannabis use disorder and the interaction of THC with dopamine neurotransmission is complex. It is important to investigate the recovery from cannabis-induced psychosis and its effects on the brain’s dopamine neurotransmission. This study was to evaluate dopamine receptor D 2 availability in the striatum (caudate/putamen) in recently...
October 13, 2023Michael Inzlicht, Taylor Bridget Sparrow-Mungal, Gregory John Depow1 citation
preprint
Approximately 200 million people consume cannabis annually, with a significant proportion of them using it chronically. Using experience sampling, we describe the effects of chronically getting high on emotions, motivation, effort, and self-regulation in everyday life. We queried chronic users (N=260) 5 times per day over 7 days (3,701 observations) to assess immediate effects of getting high...
Cannabis sativa L. is a widely used recreational drug in Togo, especially among young people. However, little is known about its chemical composition in Sub-Saharan Africa, and specifically in Togo. This study aimed to determine the levels of phytocannabinoids, specifically Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in cannabis samples collected from various towns in Togo using gas...
OBJECTIVE Cannabis is one of the most widely used substances, and although the literature shows that it affects users' cognition, it is unclear how much that impact is affected by factors such as motivation. Previous studies utilizing validity measures showed that user motivation to perform well positively impacts California Verbal Learning Test - II performance, which was higher in cannabis...
Background: Cannabis sativa is a psychoactive plant indigenous to Central and South Asia, traditionally used both for recreational and religious purposes, in addition to folk medicine. Cannabis is a rich source of natural compounds, the most important of which are commonly known as cannabinoids that cause a variety of effects through interaction with the endocannabinoid system. Materials and...