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Ayahuasca research published in 2025

108 studies whose primary subject is ayahuasca were published in 2025, up from 95 in 2024. Newest first. Back to the ayahuasca overview

Studies

La representación de la ayahuasca en los relatos polacos disponibles en Internet. Una aproximación introductoria

Ameryka Łacińska Kwartalnik analityczno-informacyjny December 30, 2025 Anna Zaczkiewicz

Este artículo analiza la representación y reconfiguración de la ayahuasca en relatos polacos difundidos a través de YouTube. Mediante un análisis cualitativo de testi-monios publicados entre enero y abril de 2022, se contrastan las experiencias de ciudada-nos polacos participantes en ceremonias en América Latina y Europa con las descripciones etnográficas del uso indígena amazónico. El estudio...

USO DA AYAHUASCA NO BRASIL: UMA ANÁLISE DE UMA DÉCADA

Revista Multidisciplinar do Nordeste Mineiro December 28, 2025 Marcos Lorran Paranhos Leão, Estácio Amaro Da Silva Júnior

A ayahuasca é uma bebida psicoativa de origem amazônica, tradicionalmente utilizada por povos indígenas e por religiões de matriz brasileira, cuja composição combina plantas ricas em N,N-dimetiltriptamina (DMT) e alcaloides β-carbolínicos. Nas últimas décadas, observa-se crescente interesse científico acerca de seus potenciais efeitos terapêuticos, especialmente no campo da saúde mental, bem...

Conocimientos locales, prácticas y usos contemporáneos atribuidos a la ayahuasca en el noroeste de la Amazonia peruana

Boletín de la Sociedad Argentina de Botánica December 23, 2025 E. Hanz Rodríguez-cabrera, M. Alejandra Romero Van-Heurck, Ani T. Cruz-Garcia et al.

Introducción y objetivos: La ayahuasca es una bebida tradicionalmente empleada con fines curativos, tanto físicos como espirituales. Su uso se ha popularizado globalmente, generando interés turístico y una creciente demanda. Esta investigación tuvo como objetivo documentar y analizar los conocimientos locales, las prácticas asociadas a la toma y los usos contemporáneos de la ayahuasca en el...

Otherwise Ayahuasca Expressions. Ritual Reinvention and Social Change in Ayahuasca Rituals

Studia Religiologica December 19, 2025 Piera Talin

This article examines a range of hybrid, artistic ayahuasca ritual formations that I define as otherwise ayahuasca expressions to engage with the question of ritual reinvention. Given the kaleidoscopic multiplicity in the diffusion of the Amazonian psychoactive plant brew ayahuasca, this article argues that ritual forms navigate the tension between fixity and flexibility, and that ritual change...

DOI: 10.4467/20844077sr.25.006.22458 (opens in new tab) Ayahuasca Ethnography Social anthropology Aesthetics +5

The Santo Daime without Daime Tactics, Agency, and Ritual Change in Ayahuasca Religions under Prohibition in Italy

Quotidiana December 17, 2025 Piera Talin

This article examines how ayahuasca religions in Italy have reconfigured their ritual practices following the 2022 legal ban on ayahuasca, including replacing the brew with water and creating new forms of religious travel. The Amazonian psychoactive brew ayahuasca, traditionally used in Indigenous rituals and healing, is at the centre of transnational religions that have spread globally....

Brujería capitalista y turistas pishtaco

Anthropologica December 16, 2025 Doriane Sabine Slaghenauffi

La aparición del «turismo chamánico» en algunas comunidades y zonas urbanas shipibo-konibo ha provocado un incremento de las prácticas brujeras vernáculas, ahora integradas en el nuevo contexto sociológico de la comercialización del chamanismo vegetalista local. Este clima provoca ataques de brujería tanto a los chamanes rivales como a los turistas que buscan una experiencia chamánica y...

EFEITOS DO USO RITUALÍSTICO E TERAPÊUTICO DA AYAHUASCA NO MANEJO DA DEPRESSÃO EM INDIVÍDUOS ADULTOS: UMA REVISÃO NARRATIVA

Revista fisio&terapia December 11, 2025 Diogo da Conceição Silva, Inaê Bartoli Azevedo, Renato Araújo de Lima et al.

Introdução: A depressão, uma condição psiquiátrica multifacetada, é caracterizada por uma combinação de sintomas emocionais, cognitivos e físicos, afetando milhões de indivíduos em todo o mundo, impactando significativamente sua qualidade de vida e produtividade. Os tratamentos alopáticos muitas vezes trazem efeitos colaterais severos, o que estimula a busca por outras formas de tratamento,...

Network Rerouting Under Ayahuasca: Temporally and Hemisphere-Resolved EEG Connectomics

bioRxiv (Cold Spring Harbor Laboratory) December 11, 2025 Caroline L. Alves, Fernanda Palhano-Fontes, Thaise G. L. de O. Toutain et al. preprint

Abstract Ayahuasca profoundly alters conscious experience, yet robust, time-resolved EEG markers of its network-level effects remain limited. We combined machine learning with complex-network analysis to quantify how functional connectivity reorganizes across time and hemispheres in resting-state EEG from a randomized, double-blind, placebo-controlled trial including three 5-min sessions:...

DOI: 10.64898/2025.12.08.693032 (opens in new tab) Electroencephalography Connectomics Pipeline software Centrality +12

Predicting and exploring ayahuasca effects: Perception, mind-wandering, and EEG oscillations

Journal of Psychopharmacology December 4, 2025 Natan Silva-Costa, Jéssica Andrade Pessoa, Kátia Cristina Andrade et al.

Background: Psychedelics induce profound changes in perception and thinking; however, little is known about the neural mechanisms and prediction of these effects. Aims: Investigating ayahuasca-induced experiences, mind-wandering, and electroencephalogram (EEG) oscillations, beyond the prediction of subjective experiences by baseline EEG. Methods: In a randomised, double-blind,...

Resilience and Brain Changes in Long-Term Ayahuasca Users: Insights From Psychometric and fMRI Pattern Recognition.

Journal of Magnetic Resonance Imaging December 1, 2025 Lucas Rego Ramos, Orlando Fernandes, Tiago Arruda Sanchez 1 citation

Ayahuasca is an Amazonian psychedelic brew that contains dimethyltryptamine (DMT) and beta carbolines. Prolonged use has shown changes in cognitive-behavioral tasks, and in humans, there is evidence of changes in cortical thickness and an increase in neuroplasticity factors that could lead to modifications in functional neural circuits. To investigate the long-term effects of Ayahuasca usage...

DOI: 10.1002/jmri.70063 (opens in new tab) Full text (opens in new tab) Ayahuasca Emotion regulation Machine learning Pattern recognition

Hepatite autoimune induzida por chá de Ayahuasca: relato de caso

Brazilian Journal of Health Review November 28, 2025 Stella Bianchini Borges, Nayara Peres Aguiar, Ana Flávia Carrijo Chiovato

Introdução: As lesões hepáticas induzidas por drogas (DILI) e por ervas (HILI) representam desafios diagnósticos e terapêuticos significativos, especialmente quando mimetizam quadros de hepatite autoimune (HAI). A discussão busca contribuir para o reconhecimento clínico dessas entidades e para o manejo seguro em contextos de uso crescente de fitoterápicos e substâncias enteógenas. Relato do...

Ayahuasca e religiosidade

Ambivalências November 26, 2025 Aldemir Inácio de Azevedo, Cláudia Mirella Pereira Ramos

Com base na trajetória dos autores como membros de um grupo que realiza o uso religioso da ayahuasca, apresentamos uma narrativa autoetnográfica Interpretando percepções, significados e experiências vividas. Inicialmente, são examinados registros bibliográficos que abordam as práticas espirituais associadas à bebida, desde suas origens entre povos Indígenas da Amazônia até sua disseminação no...

DOI: 10.21665/2318-3888.v13n26p183 (opens in new tab) Ayahuasca Context archaeology Hallucinogen Exploratory research +1

Investigating Safety Concerns and Harm Reduction in Entheogenic Churches: The Case for Community-Based Participatory Research.

Current Topics in Behavioral Neurosciences November 22, 2025 Maha N. Mian, Allison R. Coker, Grace Kretzer et al.

Alongside the important contributions of the harm reduction movement to improving public health in secular settings, communities that use psychedelics as religious sacraments (i.e., entheogens) have developed their own frameworks for supporting safety within their spiritual practices and hold their own conceptualizations of risk and harm. In order to understand better the lived realities of...

DOI: 10.1007/7854_2025_607 (opens in new tab) Full text (opens in new tab) Ayahuasca Community advisory board Community-based participatory practices Entheogens +6

Exploring the first use of psychedelic macrodoses in Latin American adults: Sociodemographic profiles, consumption factors, and subjective experiences

Journal of Psychedelic Studies November 20, 2025 Oscar Véliz-García, Marcos Domic-Siede

Abstract This study explores the first-time use of psychedelic macrodoses among Latin American adults, addressing a gap in the literature regarding naturalistic use outside clinical settings. A total of 4,810 participants from six Latin American countries completed an online survey assessing sociodemographic characteristics, substances used, consumption contexts, motivations, and subjective...

Ayahuasca como adyuvante en el tratamiento de la depresión y la ansiedad: revisión de la literatura

Ciencia y Educación November 18, 2025 Katherine Michelle Haro Haro, Jessica Mariana Freire Montesdeoca preprint

El objetivo de este trabajo es evaluar la factibilidad del uso de la ayahuasca como adyuvante en el tratamiento de la depresión y la ansiedad, analizando su impacto en la mejora de la sintomatología, de esta forma se realizó una revisión bibliográfica empleando el modelo PRISMA 2020, la búsqueda se centró en ensayos clínicos controlados, estudios observacionales y revisiones sistemáticas...

A qualitative study of long-term members of ayahuasca spiritual communities in the United States: Motivations, practices, experiences and beliefs

Journal of Psychedelic Studies November 18, 2025 Joseph T. la Torre, Ariana Kam, Todd Youngs et al.

This novel qualitative study examines the lived experiences of long-term participants in ayahuasca spiritual communities (ASCs) in the United States. Semi-structured interviews ( n = 11) were analyzed using reflexive thematic analysis indicating that these communities (1) attract individuals seeking healing from trauma, addiction, and psychological distress, while offering a sense of belonging...

Dimethyltryptamine and harmine, components of ayahuasca, prevented cocaine-induced apoptosis in SH-SY5Y human neuroblastoma cells

Archives of Toxicology November 12, 2025 Gilles Salles, Carolina Aparecida de Faria Almeida, Isabella de Carvalho Alves et al.

Ayahuasca is a psychoactive brew traditionally used in religious rituals by indigenous Amazonian populations and South American syncretic religions such as Santo Daime and União do Vegetal. Its psychoactive effects are primarily due to N,N-dimethyltryptamine (DMT), while harmine (HRE), a β-carboline alkaloid, inhibits monoamine oxidase (MAO), enabling DMT's oral bioavailability. Recent studies...

DOI: 10.1007/s00204-025-04208-8 (opens in new tab) Ayahuasca Harmine Apoptosis Flow cytometry +13

Intact neurophysiological markers of death denial in long-term ayahuasca users

Psychopharmacology November 10, 2025 Yair Dor-Ziderman, Jonathan David, Aviva Berkovich-Ohana

These findings provide preliminary evidence that while ayahuasca may alter how humans interact with the theme of death on conceptual and affective levels of cognitive processing, on automatic, perceptual unconscious levels of self-specific processing, death-denial processes appear to remain intact.

Development of a physiologically based pharmacokinetic model of N,N-dimethyltryptamine, harmine, and their interactions from ayahuasca in rats and humans.

Toxicological sciences : an official journal of the Society of Toxicology November 1, 2025 Naphat Wittayakarn, Yu-Mei Tan, Pattanachai Choomalaiwong et al.

Ayahuasca is a traditional Amazonian brew composed of Psychotria viridis, containing N,N-dimethyltryptamine (DMT), and Banisteriopsis caapi, which includes harmala alkaloids such as harmine. Ayahuasca can produce potent psychoactive effects primarily due to DMT, whose metabolism is inhibited by harmine via monoamine oxidase-A enzymes. This inhibition increases DMT's systemic bioavailability,...

DOI: 10.1093/toxsci/kfaf118 (opens in new tab) Full text (opens in new tab) Ayahuasca Banisteriopsis caapi Psychotria viridis N,N-Dimethyltryptamine +2