A resolução de problemas por uma nova cadeia de respostas ocorre quando, diante de uma situação problema, é emitida uma nova resposta resultante do encadeamento de duas ou mais respostas aprendidas independentemente. Objetivo: avaliar a influência da ayahuasca nesse processo. Metodologia: foram utilizados 12 ratos machos da linhagem wistar divididos em 3 grupos: crônico, agudo e controle. O...
\n Alucinógenos (ALU) são substâncias psicoativas que não induzem o indivíduo à dependência, possuem perfil de segurança de uso mais alto quando comparado a outras drogas e baixa capacidade de causar tolerância ao uso. Estudos recentes propõem o uso de ALU como tratamento a algumas doenças e transtornos relacionados ao sistema nervoso central, como a depressão, ansiedade e dependência. Dentre...
In the drug development, the formation of highly selective ligands has been unsuccessful in the treatment of central nervous system disorders. Multi-target ligands, from the polypharmacology paradigm, are being proposed as treatments for these complex disorders, since they offer enhanced efficacy and a strong safety profile. Natural products are the best examples of multi-target compounds, so...
El presente artículo aborda la disposición poética y barroca presente en el rito de la ayahuasca, en el que el poeta argentino Néstor Perlongher participó. Desde su perspectiva existen diversas tensiones experimentadas en el ritual chamánico, las que se organizan en tres parejas contradictorias: fuerza y forma, apolíneo y dionisíaco, cuerpo y expresión. Estas tensiones llevan al sujeto y /o...
A Ayahuasca é uma bebida enteógena feita por meio da união de duas plantas: um cipó chamado Mariri (Banisteriopsis caapi) e as folhas de uma árvore chamada Chacrona (Psychotria viridis). O Chá Ayahuasca vem sendo usado há milhares de anos em rituais religiosos indígenas, e há algumas décadas em religiões urbanas como o Santo Daime e a União do Vegetal. A Ayahuasca é considerada uma bebida...
Suicide is a major public health problem. Given increasing suicide rates and limitations surrounding current interventions, there is an urgent need for innovative interventions for suicidality. Although ayahuasca has been shown to target mental health concerns associated with suicidality (i.e., depression and hopelessness), research has not yet explored the impact of ayahuasca on suicidality....
Ayahuasca is a psychoactive beverage commonly consumed by indigenous people of the Amazon, traditionally used in religious and medicinal rituals. Nowadays, the infusion is often consumed by non-indigenous people due to its popularization. Scientific research corroborates the indigenous belief on the beverage’s healing powers when it comes to psychoneurological disorders. It is verified that a...
Ayahuasca is a hallucinogenic infusion used in religious rituals that has serotoninergic properties and may be a potential therapeutic option for drug addiction. In this study, Wistar rats had intermittent access to ethanol for 8 weeks, receiving water (control), naltrexone (NTX, 2 mg/kg body weight [bw] intraperitoneally [i.p.]) or ayahuasca (Aya) at 0.5x, 1x, or 2x the ritual dose in the...
Ayahuasca is a psychoactive beverage prepared traditionally from a mixture of the leaves and stems of Psychotria viridis and Banisteriopsis caapi, respectively, being originally consumed by indigenous Amazonian tribes for ritual and medicinal purposes. Over the years, its use has spread to other populations as a means to personal growth and spiritual connection. Also, the recreational use of...
The jaguar Panthera onca is threatened across much of its range, due to habitat loss, retaliatory killings, and poaching. Consequently, it is listed as near threatened on the IUCN Red List (Quigley et al. , 2017). There is evidence of a growing trade in jaguar body parts across Latin America, particularly in Brazil, Bolivia, Suriname, Costa Rica, and Peru (Berton, 2018). For example, on...
Introduction: Illicit substance use is an increasing problem all over the world, especially in adolescents and young adults. It is a challenge to make a definitive diagnosis of a specific substance in a poisoning case without toxicology laboratory confirmation. We confirmed the presence of N,N-dimethyltryptamine (DMT) by liquid chromatograph tandem mass spectrometer (LC/MS/MS) in biologic...
Ayahuasca, a plant-based hallucinogen that serves as a spiritual medicine in South America, has improved depression in at least one placebo-controlled clinical trial. Case studies suggest that dramatic behavioral changes often follow the Ayahuasca ceremony, but most explanations of antidepressant effects focus on changes in mindfulness. This study investigated whether both mindfulness and...
Abstract Background Neuroimaging studies have just begun to explore the acute effects of psychedelics on large-scale brain networks’ functional organization. Even less is known on the neural correlates of subacute effects taking place days after the psychedelic experience. This study explores the subacute changes of primary sensory brain networks and networks supporting higher-order affective...
Abstract Introduction and Aims A previous observational study of ayahuasca‐assisted therapy demonstrated statistically significant reductions in self‐reported problematic cocaine use among members of an Indigenous community in Canada. This paper aims to qualitatively explore the impact of ayahuasca‐assisted therapy on addiction and other substance use‐related outcomes and elucidate the lived...
Background and aims Ayahuasca is a psychedelic decoction prepared from two (or more) plants containing monoamine oxidase inhibitors, N , N -dimethyltryptamine, and other chemicals. Ayahuasca has apparently been used for centuries in the Amazon basin of South America, and in recent years has increasingly been used internationally in diverse contexts. This study aims to elucidate differences...
Ayahuasca is a psychoactive plant mixture used in ceremonial contexts throughout Western Amazonia. Its use has expanded globally in recent decades and become popular among westerners who travel to the Peruvian Amazon in increasing numbers to experience its reportedly healing effects. Through a review of relevant literature on Amazonian shamanism, combined with the authors' ethnographic data...
A range of studies has demonstrated the efficacy of the psychoactive Amazonian brew ayahuasca in addressing substance addiction. These have revealed that physiological and psychological mechanisms are deeply enmeshed. This study will focus on how interactive ritual contexts support the healing effort. This will be an ethnographically grounded, qualitative analysis of addiction-recovery...
Este estudo foi realizado na cidade de Iquitos (Amazônia peruana), onde a maioria dos curandeiros indígenas usa a bebida psicotrópica ayahuasca, a qual deve seus potentes efeitos principalmente à mistura de duas plantas, Banisteriopsis caapi (Spruce ex Griseb.) C.V. Morton e Psychotria viridis Ruiz & Pav. O brebaje palo é uma bebida psicotrópica alternativa, que provoca efeitos similares aos da...
Este ensaio tem a finalidade de refletir sobre fenômenos culturais e etnológicos condizentes aos saberes e perspectivas ameríndios acerca do uso de substâncias enteogénicas, tangencialmente, da bebida ayahuasca, cujas matrizes repousam em contextos indigenistas, desde tempos pré-colombianos. Igualmente, visamos discorrer sobre o curandeirismo vegetalista em áreas rurais e urbanas fenômeno, onde...
Objective: Ayahuasca tea contains N, N-dimethyltryptamine (DMT) found in the leaves of the Psychotria viridis vine and -carbolines found in Banisteriopsis caapi.Case Report: A 59-year-old man was brought to the emergency department due to hallucinations, agitated behavior, aggression , nausea and vomiting developing 1.5 h after drinking approximately one tea glassful of Ayahuasca tea....