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Anxiety research published in 2026

517 studies whose primary subject is anxiety have been published so far in 2026. Newest first. Back to the anxiety overview

Studies

Mindfulness and anxiety among young family caregivers: the mediating roles of psychological flexibility and self-compassion

Frontiers in Psychology October 23, 2026 Yunfu Liu, Shuai Zhong, Cheng Yang

Introduction: During critical developmental periods, young family caregivers frequently take on unpaid caregiving for family members who are physically ill, have disabilities, or have mental health conditions. Ongoing caregiving pressure may be associated with a greater risk of anxiety and poorer mental health. Psychological flexibility and self-compassion reflect distinct but interrelated...

Effects of a preventive mindfulness intervention on perceived stress and anticipatory anxiety before first clinical training in nursing students: A preregistered randomized controlled trial

Research Square October 22, 2026 Hanae Tainaka, Sachiko Nagaya, Taeko Muramatsu et al. preprint

Abstract Background Clinical training is a significant stressor for nursing students, and those facing their first placement are particularly vulnerable. This preregistered randomized controlled trial (RCT) evaluated whether a 6-week mindfulness program delivered before first clinical training could prevent stress and anxiety. Methods Twenty-nine nursing students were randomly assigned to the...

Beyond Symptom Reduction: Interconnectedness and Self-Transcendent Emotions During MDMA Sessions Predict Flourishing, Not Symptom Change, in Social Anxiety Disorder Treatment

October 20, 2026 Christina Chwyl, Mary K. Lear, Jason B. Luoma preprint

By fostering certain self-transcendent experiences (STE)—those characterized by interconnectedness and other-oriented emotions—3,4-Methylenedioxymethamphetamine (MDMA)-assisted therapy (MDMA-AT) has been hypothesized to disrupt social anxiety disorder maintenance processes, including negative self-focus, self-criticism, and isolation, thereby enhancing wellbeing. This secondary analysis used...

Mindful Awareness as a Mediator Between Social Appearance Anxiety and Social Media Addiction in Adolescents.

Journal of Psychosocial Nursing and Mental Health Services October 19, 2026 Suheyla Yurt, Şeyma Laloğlu, Nurgul Karakurt et al.

Purpose: Adolescence is a critical period for identity formation and social development, and social media can shape appearance perceptions and social acceptance. Social appearance anxiety may be associated with greater vulnerability to social media addiction, whereas mindful awareness may be linked to lower levels of this risk. The current study tested mindful awareness as a mediator between...

Serotonin 1B receptors expressed on forebrain excitatory neurons mediate the post-acute anxiolytic response to psilocybin in mice.

Psychopharmacology October 17, 2026 Sixtine Fleury, Yian Shang, Katherine M. Nautiyal

Psilocybin can produce rapid and sustained antidepressant-like and anxiolytic effects, yet the receptor and circuit mechanisms underlying these behavioral changes remain unclear. While the serotonin 2A receptor mediates psilocybin's acute psychedelic effects, psilocin (the active metabolite of psilocybin) binds many serotonin receptor subtypes. Our prior work has identified the serotonin 1B...

Research on the construction of an adaptive mindfulness-based cognitive therapy system based on large language models and its efficacy in addressing college students’ anxiety

Frontiers in Psychology October 16, 2026 Yunlong Jia

To handle the problem of resource scarcity and lack of personalization and adaptability in the traditional approach to mindfulness-based cognitive therapy (MBCT) in dealing with college students with anxiety disorders, this study proposes the use of the natural language interface and adaptability properties of large language models (LLMs) to come up with an intelligent college-level MBCT...

Effects of Mindfulness-Based Stress Reduction Combined With Perioperative Refined Nursing on Postoperative Sleep Disturbances, Anxiety, and Depression in Patients Undergoing Coronary Artery Bypass Grafting

Actas Españolas de Psiquiatría October 15, 2026 Huajun Yao, Caihong Peng, Min Wu

Background:To assess whether integrating mindfulness-based stress reduction (MBSR) into refined perioperative nursing is associated with improvements in postoperative sleep disturbances, anxiety, and depression in patients undergoing coronary artery bypass grafting (CABG). Methods: We retrospectively reviewed 146 CABG patients treated at Ruijin Hospital, Shanghai Jiao Tong University School of...

Effect of mindfulness breathing versus acupoint stimulation on anxiety, fatigue, and sleep quality among children undergoing stem cell transplantation: a three-arm randomized controlled trial

Frontiers in Medicine October 14, 2026 N. Magor, Abdelaziz Hendy, S. Ads et al.

Children undergoing hematopoietic stem cell transplantation (HSCT) commonly experience anxiety, fatigue, and sleep disturbances, which may negatively affect their quality of life and recovery. Non-pharmacological interventions, including mindfulness breathing and acupoint stimulation, have emerged as supportive approaches for symptom management. This study evaluated and compared the effects of...

Acute Ultra Low Dose THC Attenuates Anxiety-Like Behavior in a Mouse Model for Major-Depressive Disorder

Journal of Molecular Neuroscience October 12, 2026 Meitar Grad, Hadas Volkov, Noam Shomron

Abstract Major depressive disorder (MDD) is a prevalent psychiatric disorder, and is a leading cause of disability worldwide. Current treatments for MDD entail many side effects, and include a lag until the onset of therapeutic effects. The current hypotheses as for the etiology of MDD revolve around the monoamine hypothesis and the plasticity and neurodegeneration hypothesis. According to the...

Mindfulness for maternal health: A systematic umbrella review of effectiveness for addressing depression and anxiety symptoms

Journal of Affective Disorders Reports October 11, 2026 Elizabeth K. Stierman, Sarah Clifford, Briana E. Kramer et al.

Objective This umbrella review synthesizes evidence about the effectiveness of mindfulness interventions to improve mental health during pregnancy and postpartum. Methods We searched MEDLINE/PubMed, Scopus, Embase.com, PsycInfo, CINAHL, and the Cochrane Database of Systematic Reviews for systematic reviews published between January 1, 2015 and June 26, 2026. We included reviews of randomized...

The Influence of Combined Relaxation Meditation and Dynamic Exercise on Anxiety Levels among Beginner Soccer Players

PENJAGA : Pendidikan Jasmani dan Olahraga October 10, 2026 Yoga Bayu Kusuma, H. Hayati, Shandy Pieter Pelamonia et al.

Anxiety is a psychological condition that can affect a soccer player's readiness for a match, particularly among novice players who are still developing their skills and competitive experience. This study aimed to analyze the effect of a combined intervention meditation based relaxation and dynamic exercises on the anxiety levels of novice soccer players. A quantitative approach with a...

DT120 (MM120): a single-dose orally disintegrating formulation of lysergide tartrate for generalized anxiety disorder

Expert Review of Neurotherapeutics October 8, 2026 Wiesław Jerzy Cubała

Introduction Generalized anxiety disorder (GAD) is a chronic, disabling condition for which currently available pharmacotherapies have delayed onset, incomplete remission rates, treatment-emergent adverse effects and substantial real-world discontinuation. DT120, formerly MM120, is an investigational orally disintegrating tablet formulation of lysergide tartrate being developed as a single-dose...

Insomnia and anxiety exhibit distinct short-term associations following ketamine in treatment-resistant depression

Translational Psychiatry October 6, 2026 Nadia S. Hejazi, Mina Kheirkhah, Robin Chholak et al.

Insomnia and anxiety frequently co-occur with treatment-resistant depression (TRD). This study examined short-term changes in depression, anxiety, and insomnia symptoms post-ketamine in TRD and their inter-relationships. Seventy-one patients with TRD were assessed at baseline and 24 h after intravenous ketamine (0.5 mg/kg). Depression, anxiety, and insomnia were measured using the...

Effects of A Smartphone-Delivered Mindfulness Program on Pre-Competition Anxiety and Self-Efficacy in Competitive Sprinters

Journal of Sports Science and Medicine October 5, 2026 Bo Wang, Zhuzhu Wang, Xiaoming Guan

This study tested a self-report psychological intervention in an 8-week app-based mental training program (MindSprint) using a two-arm, parallel randomized controlled trial involving 70 track athletes allocated to an intervention group (n = 35) or waitlist control (n = 35) and assessed at baseline (T0), week 4 (T1), week 8 (T2), and week 12 follow-up (T3). Five participants withdrew from the...

Psychological and physiological changes following a mindfulness-based intervention integrating breathing training and HRV biofeedback in adults with anxiety disorders

Scientific Reports October 3, 2026 Yi-Chun Lin, Chien-Chih Chen, Yu-Li Lan

Anxiety disorders are associated with psychological dysregulation and autonomic imbalance. Although mindfulness-based interventions and breathing training have shown potential benefits for anxiety management, evidence regarding their integrated psychological and physiological outcomes remains limited. To examine psychological and physiological changes following a four-week mindfulness-based...

Acute ayahuasca administration attenuates binge‐like eating and anxiety‐related behaviors in mice subjected to intermittent fasting

Journal of Neuroendocrinology October 1, 2026 Cristian Ferreira Corona, Felipe Alves Alencar Lima, Jessica Sabrina Canedo da Silva Sumensse et al.

Abstract Human binge eating disorder is characterized by recurrent episodes of excessive food consumption accompanied by loss of control and is strongly associated with alterations in reward processing and emotional regulation. Ayahuasca, a psychoactive botanical preparation traditionally used in Amazonian medicine, has been shown to modulate serotonergic signaling and reward‐related behaviors...

Efficacy of Mindfulness-Based Interventions on Anxiety and Sleep Quality in Patients with Breast Cancer: A Systematic Review and Meta-Analysis

Journal of Integrative and Complementary Medicine October 1, 2026 Yongmi Lee, Hyunju Kang, Myoungsuk Kim

Introduction: Patients with breast cancer commonly experience anxiety and sleep disturbance during and after treatment, and these symptoms are closely interrelated, negatively affecting the quality of life. Mindfulness-based interventions (MBIs) have been increasingly used as a nonpharmacological supportive approach. This systematic review and meta-analysis aimed to evaluate the effects of MBIs...

A Meta-Analysis of Domestic and International Studies on the Effects of Meditation Programs for Cancer Patients: Focusing on Depression, Anxiety, Pain, and Quality of Life

Korea Exercise Rehabilitation Welfare Association September 30, 2026 Do-Hyeok Jang, Sungh-Ho Hwang

This meta-analysis aimed to examine the effects of meditation-based interventions on psychological and physical outcomes in cancer patients. A total of 25 studies were included after a systematic literature search. Random-effects models were used to calculate pooled effect sizes (Hedges’ g), and meta-regression analyses were conducted to explore the moderating effects of the number of sessions,...

The Effect of Islamic Prayer and Meditation on Reducing Stress and Anxiety

Integrated Journal for Research in Arts and Humanities September 30, 2026 Fraidoon Rahmani

One of the most widespread psychological disorders of the modern era includes stress and anxiety, which has a negative impact on the psyche, lifestyle, and personal and social interactions. In recent years, along with conventional treatment methods, more interest has been shown in spiritual and religious capabilities as complementary methods of developing mental health. This research article...

Mindfulness-Based Cognitive Therapy for Anxiety, Depressive Symptoms and Psychological Distress in Women with Breast Cancer: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Journal of Personalized Medicine September 30, 2026 Joshuan J. Barboza, Alma Delia Santiago Mijangos, Junior Smith Torres-Román et al.

Background/Objectives: Psychological distress, anxiety, depressive symptoms and fear of cancer recurrence affect many women treated for breast cancer and often persist beyond active treatment. Mindfulness-based cognitive therapy (MBCT) is manualised and can be delivered in groups or over the internet, which makes it a candidate component of personalised supportive care, but its effect has not...