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Ayahuasca research published in 2020

71 studies whose primary subject is ayahuasca were published in 2020, up from 42 in 2019. Newest first. Back to the ayahuasca overview

Studies

When Sacred Plants Turn into Resources. Review of “Cull of Personality: Ayahuasca, Shamanism and the Death of the Healer” by Kevin Tucker Black, Black and Green Press: Denver 2019, 208 pages

Ethnologia Polona December 18, 2020 Zuzanna Sadowska

Cull of Personality: Ayahuasca, Shamanism and the Death of the Healer tells a story of colonial encounters with different worlds, with a primary focus on the processes associated with turning human and non-human others into resources. Along with Christopher Columbus’ “discovery” of the New World and the signing of the Treaty at Tordesillas, which divided its territory between European empires,...

Lectotypification of Banisteriopsis caapi and B. quitensis (Malpighiaceae), names associated with an important ingredient of Ayahuasca

Taxon December 11, 2020 Regina Célia de Oliveira, Júlia Sonsin‐oliveira, Thaís Aparecida Coelho Dos Santos et al. 6 citations

Abstract Ritually used in religious ceremonies and now popular culture, Banisteriopsis caapi (≡ Banisteria caapi ) is the most important ingredient in an inebriating drink known as Ayahuasca. The nomenclatural history of B. caapi and B. quitensis is presented, and both names are lectotypified.

Avaliação da variação morfológica, anatômica e fitoquímica de >i/i< (Spruce ex Griseb.) C.v. Morton e >i/i< Ruiz & Pav em diferentes ambientes, teor de alcaloides e citotoxicidade do chá Ayahuasca

December 10, 2020 Ordilena Ferreira de Miranda

\n B. caapi e P. viridis são plantas de origem amazônica e as principais espécies preconizados para preparação do chá Ayahuasca. Um chá com efeitos enteogênico e psicotrópico de uso milenar pelos povos indígenas da Amazônia, preparado pela decocção de caules de B. Caapi, que apresenta os alcaloides β-carbolínicos harmina (HRM), harmalina (HRL) e tetrahidrohramina (THH), e folhas de P. viridis...

A Systematic Literature Review of the Potential Therapeutic Effects of Ayahuasca Tea Prepared From the Use of Banisteriopsis Caapi and Psychotria Viridis

Journal of Agricultural Studies December 10, 2020 Adriane Cordeiro Trevisani, João Pedro Cordeiro Trevisani, Moacir Haverroth et al. 1 citation

Ayahuasca is a drink of indigenous origin made as a decoction obtained from medicinal plants found mainly in Acre, state of Brazil, which are the leaves of Psychtoria viridis, popularly known as “chacrona” in Brazil, and the stem of Banisteriopsis caapi, commonly known as mariri or jagube. The decoction is used in religious practices for the therapy of diseases that affect the human being, such...

DOI: 10.5296/jas.v9i1.17910 (opens in new tab) Ayahuasca Traditional medicine Antiparasitic Antimicrobial

Acute and subacute psychoactive effects of Kambô, the secretion of the Amazonian Giant Maki Frog (Phyllomedusa bicolor): retrospective reports

Scientific Reports December 9, 2020 Timo Torsten Schmidt, Simon Reiche, Caroline L. C. Hage et al. 12 citations

Kambô, the secretion of the Amazonian Giant Leaf Frog (Phyllomedusa bicolor) contains a plethora of bioactive peptides and was originally used by indigenous communities from the Amazon basin as medicine for improving hunting capacities. In the last 20 years, Kambô has spread to Western urban healing circles. To date it is still controversial whether the acute effects of Kambô include...

The ritual use of ayahuasca during treatment of severe physical illnesses: a qualitative study

Journal of Psychoactive Drugs December 7, 2020 Lucas Oliveira Maia, Dimitri Daldegan-Bueno, Luís Fernando Tófoli 33 citations

Diseases that threaten life raise existential questions that can be a source of psychological distress. Studies with psychedelics demonstrate therapeutic effects for anxiety and depression associated with life-threatening illnesses. Ayahuasca has been proposed as a possible therapeutic agent in the treatment of psychiatric disorders. Preliminary studies suggest that ayahuasca could promote...

DOI: 10.1080/02791072.2020.1854399 (opens in new tab) Ayahuasca Anxiety Thematic analysis Qualitative research +8

Examining Changes in Personality Following Shamanic Ceremonial Use of Ayahuasca

Research Square November 30, 2020 Brandon Weiss, Joshua D. Miller, Nathan T. Carter et al. 7 citations preprint

Abstract The present study examines the association between the ceremonial use of ayahuasca – a decoction combining the Banistereopsis caapi vine and N,N Dimethyltryptamine-containing plants – and changes in personality traits as conceived by the Five-Factor model (FFM); as well as the degree to which demographic characteristics, baseline personality, and acute post-ayahuasca experiences affect...

Evaluation of the Cytotoxicity of Ayahuasca Beverages

Molecules November 28, 2020 Ana Y. Simão, Joana Gonçalves, Ana Gradillas et al. 19 citations

Ayahuasca is a beverage consumed at shamanic ceremonies and currently has gained popularity on recreational scenarios. It contains beta-carboline alkaloids and N,N-dimethyltryptamine, which possesses hallucinogenic effects. Only a few studies have elicited the psychoactive effects and the dose of such compounds on neurological dopaminergic cells or animals. In this work, we aimed to study the...

DOI: 10.3390/molecules25235594 (opens in new tab) Ayahuasca Peganum harmala Cytotoxicity Dopaminergic +6

Avaliação das possíveis interações entre o canabidiol e a ayahuasca em voluntários saudáveis: um estudo randomizado, duplo-cego e controlado com placebo

November 27, 2020 Giordano Novak Rossi

A ayahuasca é uma bebida psicoativa tradicionalmente utilizada por grupos indígenas da Amazônia com fins rituais e terapêuticos. Estudos em animais e humanos sugerem que a ayahuasca possui efeitos ansiolíticos e antidepressivos. O canabidiol (CBD) por sua vez é um fitocanabinoide produzido pela planta da maconha, e tem demonstrado diversas aplicações terapêuticas nos últimos anos, incluindo...

Anti-inflammatory activity of ayahuasca: therapeutical implications in neurological and psychiatric diseases

Behavioural Brain Research November 6, 2020 Marina Goulart Da Silva, Guilherme Cabreira Daros, Rafael Mariano de Bitencourt 21 citations

Ayahuasca is a decoction with psychoactive properties, used for millennia for therapeutic and religious purposes by indigenous groups and the population of amazonian countries. As described in this narrative review, it is essentially constituted by β-carbolines and tryptamines, and it has therapeutic effects on behavioral disorders due to the inhibition of the monoamine oxidase enzyme and the...

DOI: 10.1016/j.bbr.2020.113003 (opens in new tab) Ayahuasca Hallucinogen Neuroinflammation Monoamine oxidase +2

Post-acute psychological effects of classical serotonergic psychedelics: a systematic review and meta-analysis

Psychological Medicine November 4, 2020 Simon B. Goldberg, Benjamin Shechet, Christopher R. Nicholas et al. 66 citations

Abstract Background Scientific interest in the therapeutic effects of classical psychedelics has increased in the past two decades. The psychological effects of these substances outside the period of acute intoxication have not been fully characterized. This study aimed to: (1) quantify the effects of psilocybin, ayahuasca, and lysergic acid diethylamide (LSD) on psychological outcomes in the...

Risk assessment of ayahuasca use in a religious context: self-reported risk factors and adverse effects

Brazilian Journal of Psychiatry October 30, 2020 Ícaro Durante, Rafael G. Dos Santos, José Carlos Bouso et al. 49 citations

A minority of participants reported being very negatively affected by persistent adverse effects. Psychiatric medication use while participating in ayahuasca rituals was not associated with increased adverse effects. For the most part, the institution's practices seem sufficient to prevent exacerbated reactions. Future studies may focus on negatively affected users.

Detection and Quantification of Psychoactive N,N-Dimethyltryptamine in Ayahuasca Brews by Ambient Ionization High-Resolution Mass Spectrometry

ACS Omega October 27, 2020 Megan I. Chambers, Meghan G. Appley, Cameron M. Longo et al. 17 citations

The United Nations Office on Drugs and Crime designated twenty psychoactive botanical species as "plants of concern" because of their increased recreational abuse. Four of these are used to prepare ayahuasca brews. The complexity of the plant matrices, as well as the beverage itself, make the identification and quantification of the Schedule I component, N,N-dimethyltryptamine (DMT), a...

Ayahuasca Beverages: Phytochemical Analysis and Biological Properties

Antibiotics October 24, 2020 Joana Gonçalves, Ângelo Luís, Ana Gradillas et al. 25 citations

Ayahuasca is a psychoactive beverage, originally consumed by indigenous Amazon tribes, of which consumption has been increasing worldwide. The aim of this study was to evaluate the phytochemical profile, as well as the antioxidant, anti-inflammatory and antimicrobial properties of decoctions of four individual plants, a commercial mixture and four mixtures of two individual plants used in the...

DOI: 10.3390/antibiotics9110731 (opens in new tab) Phytochemical Antimicrobial Dpph Resazurin +5

Polypharmacology or “Pharmacological Promiscuity” In Psychedelic Research: What Are We Missing?

ACS Chemical Neuroscience October 6, 2020 Genís Ona, Rafael G. Dos Santos, Jaime E. C. Hallak et al. 12 citations

Research with psychedelic drugs has mainly focused on isolated compounds. However, this approach is challenged by the "polypharmacology" paradigm. In this Viewpoint, we suggest that we may be missing something if we do not use the whole product in the case of ayahuasca or Psilocybe mushrooms. After describing how research on psychedelic drugs can be effectively combined with the...

Revisión bibliográfica de la ayahuasca y su uso terapéutico

Revista Peruana de Medicina Integrativa October 6, 2020 Edison Chávez Castillo, Cynthia Chávez Castillo, Jorge Zuquitana Godoyc 2 citations

La ayahuasca es un brebaje psicotrópico con acción serotoninérgica. Las fuentes botánicas más comunes de la ayahuasca son la Banisteriopsiscaapi y la Psychotriaviridis, en la revisión bibliográfica se buscó conocer las propiedades bioquímicas, síntomas y signos que produce esta planta, asimismo, se reconocieron los efectos que produce al ser utilizada como brebaje por los chamanes de la...

The Acute Effects of the Atypical Dissociative Hallucinogen Salvinorin A on Functional Connectivity in the Human Brain

Scientific Reports October 2, 2020 Manoj K. Doss, Darrick G. May, Matthew W. Johnson et al. 52 citations

Abstract Salvinorin A (SA) is a κ-opioid receptor agonist and atypical dissociative hallucinogen found in Salvia divinorum . Despite the resurgence of hallucinogen studies, the effects of κ-opioid agonists on human brain function are not well-understood. This placebo-controlled, within-subject study used functional magnetic resonance imaging for the first time to explore the effects of inhaled...