Prevention Science
August 1, 2022
Kate Tudor, Shannon Maloney, Anam Raja et al.
There is evidence that universal school-based mindfulness training (SBMT) can have positive effects for young people. However, it is unknown who benefits most from such training, how training exerts effects, and how implementation impacts effects. This study aimed to provide an overview of the evidence on the mediators, moderators, and implementation factors of SBMT, and propose a conceptual...
Clinical psychological science : a journal of the Association for Psychological Science
April 29, 2022
Z. Cohen, R. DeRubeis, Rachel Hayes et al.
Depression is highly recurrent, even following successful pharmacological and/or psychological intervention. We aimed to develop clinical prediction models to inform adults with recurrent depression choosing between antidepressant medication (ADM) maintenance or switching to mindfulness-based cognitive therapy (MBCT). Using previously published data (N = 424), we constructed prognostic models...
Behaviour Research and Therapy
May 25, 2021
Caitlin Hitchcock, Christina Haag, Alicia J. Smith et al.
preprint
The ability to retrieve specific, single-incident autobiographical memories has been consistently posited as a predictor of recurrent depression. Elucidating the role of autobiographical memory specificity in patient-response to depressive treatments may improve treatment efficacy and facilitate use of science-driven interventions. We used recent methodological advances in individual patient...
Mindfulness
December 2, 2020
Ruth A. Baer, Catherine Crane, Jesus Montero-Marin et al.
Evidence-based mindfulness programs have well-established benefits, but the potential for harmful effects is understudied. We explored the frequency and severity of unpleasant experiences and harm in two nonclinical samples participating in an adaptation of mindfulness-based cognitive therapy (MBCT) for the general population. Study 1 included 84 schoolteachers; study 2 included 74 university...
Mindfulness
April 29, 2019
J. Michalak, Catherine Crane, C. Germer et al.
ObjectivesMindfulness-based interventions (MBIs) like mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) teach mindfulness in a group-based format. Empirical research has shown that many therapists working in individual therapy integrate mindfulness practices (e.g., body scan, sitting meditation) into their treatments. However, research on this topic is in...
Mindfulness
January 12, 2019
A. Tickell, S. Ball, Paul Bernard et al.
Depression is common with a high risk of relapse/recurrence. There is evidence from multiple randomised controlled trials (RCTs) demonstrating the efficacy of mindfulness-based cognitive therapy (MBCT) for the prevention of depressive relapse/recurrence, and it is included in several national clinical guidelines for this purpose. However, little is known about whether MBCT is being delivered...
Journal of Child Psychology and Psychiatry
October 22, 2018
Darren Dunning, Kirsty Griffiths, Willem Kuyken et al.
596 citations
BACKGROUND: Mindfulness based interventions (MBIs) are an increasingly popular way of attempting to improve the behavioural, cognitive and mental health outcomes of children and adolescents, though there is a suggestion that enthusiasm has moved ahead of the evidence base. Most evaluations of MBIs are either uncontrolled or nonrandomized trials. This meta-analysis aims to establish the efficacy...
Behaviour Research and Therapy
May 10, 2017
Christine E. Parsons, Catherine Crane, Liam J. Parsons et al.
553 citations
Mindfulness-Based Cognitive Therapy (MBCT) and Mindfulness-Based Stress Reduction (MBSR) emphasize the importance of mindfulness practice at home as an integral part of the program. However, the extent to which participants complete their assigned practice is not yet clear, nor is it clear whether this practice is associated with positive outcomes. For this systematic review and meta-analysis,...
JAMA Psychiatry
April 28, 2016
Willem Kuyken, Fiona C Warren, Rod S. Taylor et al.
815 citations
IMPORTANCE: Relapse prevention in recurrent depression is a significant public health problem, and antidepressants are the current first-line treatment approach. Identifying an equally efficacious nonpharmacological intervention would be an important development. OBJECTIVE: To conduct a meta-analysis on individual patient data to examine the efficacy of mindfulness-based cognitive therapy...
Psychological Assessment
April 14, 2016
Jenny Gu, Clara Strauss, Catherine Crane et al.
Research into the effectiveness and mechanisms of mindfulness-based interventions (MBIs) requires reliable and valid measures of mindfulness. The 39-item Five Facet Mindfulness Questionnaire (FFMQ-39) is a measure of mindfulness commonly used to assess change before and after MBIs. However, the stability and invariance of the FFMQ factor structure have not yet been tested before and after an...
Journal of Consulting and Clinical Psychology
August 24, 2015
Thorsten Barnhofer, Catherine Crane, Kate Brennan et al.
Objective: In patients with a history of suicidal depression, recurrence of depressive symptoms can easily reactivate suicidal thinking. In this study, we investigated whether training in mindfulness, which is aimed at helping patients “decenter” from negative thinking, could help weaken the link between depressive symptoms and suicidal cognitions. Method: Analyses were based on data from a...
Clinical Psychology Review
April 1, 2015
A. M. van der Velden, Willem Kuyken, U. Wattar et al.
BACKGROUND The investigation of treatment mechanisms in randomized controlled trials has considerable clinical and theoretical relevance. Despite the empirical support for the effect of mindfulness-based cognitive therapy (MBCT) in the treatment of recurrent major depressive disorder (MDD), the specific mechanisms by which MBCT leads to therapeutic change remain unclear. OBJECTIVE By means of a...
Behaviour Research and Therapy
December 1, 2014
Catherine Crane, Rebecca S. Crane, Catrin Eames et al.
Few empirical studies have explored the associations between formal and informal mindfulness home practice and outcome in Mindfulness-based Cognitive Therapy (MBCT). In this study ninety-nine participants randomised to MBCT in a multi-centre randomised controlled trial completed self-reported ratings of home practice over 7 treatment weeks. Recurrence of Major Depression was assessed...
Journal of Consulting and Clinical Psychology
December 3, 2013
J. Mark G. Williams, Catherine Crane, Thorsten Barnhofer et al.
418 citations
OBJECTIVE: We compared mindfulness-based cognitive therapy (MBCT) with both cognitive psychological education (CPE) and treatment as usual (TAU) in preventing relapse to major depressive disorder (MDD) in people currently in remission following at least 3 previous episodes. METHOD: A randomized controlled trial in which 274 participants were allocated in the ratio 2:2:1 to MBCT plus TAU, CPE...
Cognitive Therapy and Research
January 20, 2011
Catherine Crane, Rosie Winder, Emily Hargus et al.
47 citations
This study explored the immediate effects of a course of Mindfulness-Based Cognitive Therapy (MBCT) for chronically depressed participants with a history of suicidality on the specificity of important goals for the future. Participants were randomly allocated to immediate treatment with MBCT or to a waitlist condition and life goals were assessed both before and after the treatment or waiting...
Mindfulness
December 1, 2010
Catherine Crane, Danka Jandric, Thorsten Barnhofer et al.
Conditional goal setting (CGS, the tendency to regard high order goals such as happiness, as conditional upon the achievement of lower order goals) is observed in individuals with depression and recent research has suggested a link between levels of dispositional mindfulness and conditional goal setting in depressed patients. Since interventions which aim to increase mindfulness through...
Mindfulness
March 1, 2010
Thorsten Barnhofer, Tobias Chittka, Helen Nightingale et al.
99 citations
We investigated state effects of two forms of meditation on electroencephalography prefrontal α-asymmetry, a global indicator of approach versus withdrawal motivation and related affective state. A clinical series of previously depressed individuals were guided to practice either mindfulness breathing meditation (N = 8) or a form of meditation directly aimed at cultivating positive affect,...
Mindfulness
March 2010
Catherine Crane, J Mark G Williams
We report data from a randomised controlled trial of mindfulness-based cognitive therapy to pilot procedures for people with a history of suicidal ideation or behaviour, focusing in particular on the variables that distinguish those who complete an adequate 'dose' of treatment, from those who drop out. Sixty-eight participants were randomised to either immediate treatment with mindfulness-based...
Emotion
February 1, 2010
Emily Hargus, Catherine Crane, Thorsten Barnhofer et al.
213 citations
The authors examined the effects of mindfulness training on 2 aspects of mode of processing in depressed participants: degree of meta-awareness and specificity of memory. Each of these has been suggested as a maladaptive aspect of a mode of processing linked to persistence and recurrence of symptoms. Twenty-seven depressed participants, all of whom had experienced suicidal crises, described...
British Journal of Clinical Psychology
March 2, 2009
Silvia R. Hepburn, Catherine Crane, Thorsten Barnhofer et al.
74 citations
OBJECTIVES: Thought suppression is a strategy aimed at mental control that may paradoxically increase the frequency of unwanted thoughts. This preliminary study examined effects of mindfulness-based cognitive therapy (MBCT) on thought suppression and depression in individuals with past depression and suicidality. METHODS: In a randomized controlled trial design, 68 participants were allocated...
Behaviour Research and Therapy
February 13, 2009
Thorsten Barnhofer, Catherine Crane, Emily Hargus et al.
398 citations
This pilot study investigated the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT), a treatment combining mindfulness meditation and interventions taken from cognitive therapy, in patients suffering from chronic-recurrent depression. Currently symptomatic patients with at least three previous episodes of depression and a history of suicidal ideation were randomly allocated to receive...
Journal of Affective Disorders
April 1, 2008
J.M.G. Williams, Y. Alatiq, Catherine Crane et al.
Background Bipolar disorder is highly recurrent and rates of comorbidity are high. Studies have pointed to anxiety comorbidity as one factor associated with risk of suicide attempts and poor overall outcome. This study aimed to explore the feasibility and potential benefits of a new psychological treatment (Mindfulness-based Cognitive Therapy: MBCT) for people with bipolar disorder focusing on...
Neuroreport
May 7, 2007
Thorsten Barnhofer, Danielle Duggan, Catherine Crane et al.
This study investigated the effects of a meditation-based treatment for preventing relapse to depression, mindfulness-based cognitive therapy (MBCT), on prefrontal alpha-asymmetry in resting electroencephalogram (EEG), a biological indicator of affective style. Twenty-two individuals with a previous history of suicidal depression were randomly assigned to either MBCT (N=10) or...
Journal of Clinical Psychology
December 9, 2005
J. Mark G. Williams, Danielle S. Duggan, Catherine Crane et al.
235 citations
Once suicidal thoughts have emerged as a feature of depression they are likely to be reactivated as part of a suicidal mode of mind whenever sad mood reappears. This article reviews the methods and the usefulness of mindfulness-based cognitive therapy (MBCT) as a treatment for the prevention of the reactivation of the suicidal mode. MBCT integrates mindfulness meditation practices and cognitive...