Sholto Radford

2 papers in the library · 418 citations · publishing 2013-2015

Papers

Mindfulness-based cognitive therapy for preventing relapse in recurrent depression: A randomized dismantling trial.

Journal of Consulting and Clinical Psychology December 3, 2013 J. Mark G. Williams, Catherine Crane, Thorsten Barnhofer et al. 418 citations

Mindfulness-based cognitive therapy (MBCT) plus treatment as usual (TAU) did not significantly reduce the risk of relapse to major depressive disorder over 12 months compared with cognitive psychological education (CPE) plus TAU or TAU alone among people with at least three previous episodes. The hazard ratio for MBCT versus CPE was 0.88, and for MBCT versus TAU was 0.69, both with confidence intervals crossing 1.0. However, severity of childhood trauma influenced relapse risk: each one-standard-deviation increase in trauma severity raised the hazard ratio to 1.26. Among participants with above-average childhood trauma, MBCT offered significant protection compared with TAU (hazard ratio 0.43) and a non-significant advantage over CPE. For those with below-average trauma, no differences between treatments appeared.

DOI: 10.1037/a0035036 Mindfulness-based cognitive therapy Randomized controlled trial Hazard ratio Relapse prevention +4

Mindfulness-Based Cognitive Therapy (MBCT) Reduces the Association Between Depressive Symptoms and Suicidal Cognitions in Patients With a History of Suicidal Depression

Journal of Consulting and Clinical Psychology August 24, 2015 T. Barnhofer, C. Crane, Kate Brennan et al.

Mindfulness training can weaken the link between depressive symptoms and suicidal thinking in patients with a history of suicidal depression. In a randomized trial, previously suicidal patients received mindfulness-based cognitive therapy (MBCT), an active control treatment (cognitive psychoeducation, CPE), or treatment as usual (TAU). After treatment, among patients with minimal to moderate depressive symptoms, suicidal cognitions were significantly related to symptom levels in both control groups but not in the MBCT group. This suggests that mindfulness training helps patients decenter from negative thinking, reducing a key vulnerability for relapse into suicidal depression.

DOI: 10.1037/ccp0000027 Full text Psychology Medicine