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Latent Profile Analysis of the Five Facet Mindfulness Questionnaire in a Sample With a History of Recurrent Depression

Jenny Gu, Anke Karl, Ruth A. Baer, C. Strauss, Thorsten Barnhofer, Catherine Crane

Assessment June 19, 2017 DOI: 10.1177/1073191117715114 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study using latent profile analysis Peer reviewed
Sample size 683
Population Adults with a history of recurrent depression
Measures Five Facet Mindfulness Questionnaire
Topics Depression Meditation
Key findings A four-profile solution on the Five Facet Mindfulness Questionnaire replicated across test (n = 343) and validation (n = 340) samples: "high mindfulness," "nonjudgmentally aware," "moderate mindfulness," and "very low mindfulness." "High mindfulness" was associated with the most adaptive psychological functioning and "very low mindfulness" with the least adaptive. Most people with recurrent depression showed evenly expressed mindfulness skills, though a small minority showed a replicable uneven nonjudgmental-awareness profile.

Abstract

Extending previous research, we applied latent profile analysis in a sample of adults with a history of recurrent depression to identify subgroups with distinct response profiles on the Five Facet Mindfulness Questionnaire and understand how these relate to psychological functioning. The sample was randomly divided into two subsamples to first examine the optimal number of latent profiles (test sample; n = 343) and then validate the identified solution (validation sample; n = 340). In both test and validation samples, a four-profile solution was revealed where two profiles mapped broadly onto those previously identified in nonclinical samples: “high mindfulness” and “nonjudgmentally aware.” Two additional subgroups, “moderate mindfulness” and “very low mindfulness,” were observed. “High mindfulness” was associated with the most adaptive psychological functioning and “very low mindfulness” with the least adaptive. In most people with recurrent depression, mindfulness skills are expressed evenly across different domains. However, in a small minority a meaningful and replicable uneven profile indicating nonjudgmental awareness is observable. Current findings require replication and future research should examine the extent to which profiles change from periods of wellness to illness in people with recurrent depression and how profiles are influenced by exposure to mindfulness-based intervention.

Comparable studies

Other observational and cohort studies on depression, most cited first.

Study Year Design Participants
Metacognitive awareness and prevention of relapse in depression: Empirical evidence. Residually depressed patients and nondepressed controls; recovered depressed patients 2002 Observational cohort with intervention components
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression 2017 Observational cohort n = 19
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder Patients with treatment-resistant major depressive disorder 2012 Observational cohort n = 30
Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome Healthy controls and actively depressed patients with treatment-resistant depression... 2017 Observational cohort n = 59

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