medRxiv
June 23, 2026
Paulina Clara Dagnino, Anne Maj van der Velden, Henricus G. Ruhé et al.
Abstract Major depressive disorder (MDD) is a leading cause of disability worldwide with risk of onset and recurrence linked to depressive ruminative thought patterns. Mindfulness-based cognitive therapy (MBCT) is an evidence-based treatment for depression that targets the ability to recognise, decenter, and disengage from ruminative thought patterns. Elucidating how MBCT impacts hierarchical...
Mindfulness
June 1, 2026
Anderson Yoon, Yehwi Park, Min Ah Kim et al.
Abstract Objectives Mindfulness-based cognitive therapy (MBCT) integrates cognitive therapy and mindfulness meditation to help individuals disengage from maladaptive thoughts and reactive behavioral patterns. By cultivating nonjudgmental present-moment awareness and decentering from thoughts and emotions, MBCT enhances the capacity to respond more skillfully, thereby reducing impulsivity and...
Biological Psychiatry Global Open Science
May 14, 2026
Anne Maj van der Velden, Jakub Vohryzek, Paulina Clara Dagnino et al.
BACKGROUND Depression is a prevalent and debilitating affective disorder characterised by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for recurrent depression developed specifically to target rumination and recurrence risk by training metacognitive awareness and adaptive attention, emotion and self-regulation...
JCPP Advances
October 7, 2025
Carolina Guzman Holst, Simona Skripkauskaite, Jack L. Andrews et al.
This study explored adolescent's mental health trajectories over the course of a school-based mindfulness-based intervention trial (MYRIAD). It examined whether intervention condition (mindfulness vs. teaching-as-usual), individual-level and contextual-level factors were associated with different trajectories. This pre-registered study used data from 11- to 14-year-olds who participated in the...
Journal of Consulting and Clinical Psychology
June 1, 2025
Andreas Voldstad, Ananda Zeas-Sigüenza, Anton Skolzkov et al.
2 citations
Mindfulness interventions (MIs) train nonjudgmental attention to present-moment experience and aim to improve mental health and well-being. The evidence for their effect on interpersonal relationships is promising but uncertain. This study examines the effect of MIs on couple relationship satisfaction (RS). Randomized controlled trials of MIs including RS were selected based on systematic...
The British journal of psychiatry : the journal of mental science
April 1, 2025
Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al.
4 citations
Personalised management of recurrent depression, considering individual patient characteristics, is crucial. This study evaluates the potentially different mediating role of mindfulness skills in managing recurrent depression using mindfulness-based cognitive therapy (MBCT) among people with varying depression severity. Data from the Prevention of Depressive Relapse or Recurrence (PREVENT)...
medRxiv
February 7, 2025
Jakub Vohryzek, Anne Maj van der Velden, Willem Kuyken et al.
1 citation
preprint
BACKGROUND: Depression is a prevalent and debilitating affective disorder characterised by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for recurrent depression developed specifically to target rumination and recurrence risk by training metacognitive awareness and adaptive attention, emotion and self-regulation...
Mindfulness
2025
Marc-Henri Deroche, Willem Kuyken, Teruhisa Uwatoko et al.
5 citations
This article explores the potential relevance of Mindfulness-Based Programs, particularly Mindfulness-Based Cognitive Therapy (MBCT), to support the mission of higher education by facilitating the journey from information to knowledge, and from knowledge to wisdom. It thus addresses the problems of distractibility and superficial engagement caused by information overload and aims to prepare...
Global advances in integrative medicine and health
2025
Chelsea J Siwik, Jessica M. Harrison, Willem Kuyken et al.
Mindfulness-Based Cognitive Therapy (MBCT) reduces depression relapse, yet graduates have expressed a need for structured guidance post-program to maintain mindfulness practice and sustain benefits. To address this, we created MBCT for Depression-Taking it Further (MBCT-D-TiF). To refine and pilot test feasibility and acceptability of MBCT-D-TiF. We collected qualitative focus group data to...
Psychotherapy research : journal of the Society for Psychotherapy Research
November 1, 2024
Shannon Maloney, Jesus Montero-Marin, Willem Kuyken
17 citations
To explore mediated effects of Mindfulness-Based Cognitive Therapy-"Taking it Further" (MBCT-TiF) on mental well-being through changes in mindfulness, self-compassion, and decentering. A secondary analysis of an RCT using simple mediation, with 164 graduates of MBCT and mindfulness-based stress reduction (MBSR), was implemented whereby MBCT-TiF (vs ongoing mindfulness practice; OMP) was the...
Journal of Consulting and Clinical Psychology
September 1, 2024
Barnaby D. Dunn, Laura Warbrick, Rachel Hayes et al.
10 citations
Mindfulness-based cognitive therapy (MBCT) is a viable alternative to maintenance antidepressant medication (M-ADM) to reduce risk of relapse/recurrence (RR) in recurrent depression, but its mechanism of action is not yet fully articulated. This secondary analysis of the PREVENT trial examined if MBCT with support to taper medication (MBCT-TS) reduces risk of RR in part by enhancing positive...
BMJ mental health
August 24, 2024
Shannon Maloney, Merle Kock, Yasmijn Slaghekke et al.
16 citations
Mindfulness-based programmes (MBPs) and practices have demonstrated effects in mental health and well-being, yet questions regarding the target mechanisms that drive change across the population remain unresolved. Five databases were searched for randomised controlled trials that evaluate the indirect effects (IEs) of an MBP or mindfulness practice in relation to mental health and well-being...
Behaviour Research and Therapy
February 1, 2024
Shannon Maloney, Jesus Montero-Marin, Willem Kuyken
To evaluate the effectiveness and acceptability of Mindfulness-Based Cognitive Therapy-Taking it Further (MBCT-TiF), as an adapted programme for graduates of MBCT and Mindfulness-Based Stress Reduction (MBSR). MBCT-TiF sits within a global mental health approach, which aims to help shift a wider distribution of the population towards mental well-being and away from mental ill health using a...
Global advances in integrative medicine and health
2024
Frederick M Hecht, Rebecca S. Crane, Patricia J Moran et al.
2 citations
Prior data suggests the Mindfulness-Based Interventions: (MBI) Teaching Assessment Criteria (MBI:TAC) has good inter-rater reliability, but many raters knew teacher experience level. We sought to further evaluate the MBI-TAC's inter-rater reliability and obtain preliminary data on predictive validity. We videorecorded 21 MBSR teachers from academic and community settings. We trained 19...
Biological Psychiatry
February 1, 2023
Anne Maj van der Velden, Jacqueline Scholl, Else-Marie Elmholdt et al.
Depression is a leading cause of disability worldwide and its prevalence is on the rise. One of the most debilitating aspects of depression is the dominance and persistence of depressive rumination, a state of mind that is linked to onset and recurrence of depression. Mindfulness meditation trains adaptive attention regulation and present-moment embodied awareness, skills that may be...
Mindfulness
2023
Shannon Maloney, Christina Surawy, Maryanne Martin et al.
9 citations
The primary aim was to explore state- and trait-level effects and candidate mechanisms of four Mindfulness-Based Cognitive Therapy (MBCT) practices. One hundred sixty adults self-selected from the general population were randomized to one of four mindfulness practices: body scan, mindful movement, breath and body, and befriending. Study 1 explored state-level self-compassion, mindfulness,...
Global advances in integrative medicine and health
2023
Chelsea J Siwik, Shelley R Adler, Patricia J Moran et al.
7 citations
Mindfulness-based cognitive therapy (MBCT) is an effective group intervention for reducing rates of depression relapse. However, about one-third of graduates experience relapse within 1 year of completing the course. The current study aimed to explore the need and strategies for additional support following the MBCT course. We conducted 4 focus groups via videoconferencing, two with MBCT...
Mindfulness
2023
Barnaby D. Dunn, Hanna Wiedemann, Merle Kock et al.
Abstract Objectives Mindfulness-Based Cognitive Therapy for Depression (MBCT-D) has been shown to be effective at repairing positive affect deficits in depressed individuals, but the mechanism of action underpinning these changes has not been empirically examined. To address this issue, secondary analyses of two randomised controlled trials in individuals with residual depression were...
Prevention Science
August 1, 2022
Kate Tudor, Shannon Maloney, Anam Raja et al.
There is evidence that universal school-based mindfulness training (SBMT) can have positive effects for young people. However, it is unknown who benefits most from such training, how training exerts effects, and how implementation impacts effects. This study aimed to provide an overview of the evidence on the mediators, moderators, and implementation factors of SBMT, and propose a conceptual...
Clinical psychological science : a journal of the Association for Psychological Science
April 29, 2022
Z. Cohen, R. DeRubeis, Rachel Hayes et al.
Depression is highly recurrent, even following successful pharmacological and/or psychological intervention. We aimed to develop clinical prediction models to inform adults with recurrent depression choosing between antidepressant medication (ADM) maintenance or switching to mindfulness-based cognitive therapy (MBCT). Using previously published data (N = 424), we constructed prognostic models...
Mindfulness
April 1, 2022
Hans Kirschner, Willem Kuyken, Anke Karl
Abstract Objectives In order to address an important gap in understanding mechanisms of depressive relapse, we complemented self-report with psychophysiological measures to a specifically developed brief self-compassion exercise, to examine if mindfulness-based cognitive therapy (MBCT) reduces dispositional negative self-bias in individuals with recurrent depression. Methods Individuals’...
Behaviour Research and Therapy
May 25, 2021
Caitlin Hitchcock, Christina Haag, Alicia J. Smith et al.
preprint
The ability to retrieve specific, single-incident autobiographical memories has been consistently posited as a predictor of recurrent depression. Elucidating the role of autobiographical memory specificity in patient-response to depressive treatments may improve treatment efficacy and facilitate use of science-driven interventions. We used recent methodological advances in individual patient...
International Journal of Clinical and Health Psychology
February 18, 2021
Clara Strauss, Jenny Gu, Jesus Montero-Marin et al.
Background/Objective Healthcare workers play a critical role in the health of a nation, yet rates of healthcare worker stress are disproportionately high. We evaluated whether mindfulness-based cognitive therapy for life (MBCT-L), could reduce stress in healthcare workers and target a range of secondary outcomes. Method: This is the first parallel randomised controlled trial of MBCT-L....
Mindfulness
December 2, 2020
Ruth A. Baer, Catherine Crane, Jesus Montero-Marin et al.
Evidence-based mindfulness programs have well-established benefits, but the potential for harmful effects is understudied. We explored the frequency and severity of unpleasant experiences and harm in two nonclinical samples participating in an adaptation of mindfulness-based cognitive therapy (MBCT) for the general population. Study 1 included 84 schoolteachers; study 2 included 74 university...
Mindfulness
January 12, 2019
A. Tickell, S. Ball, Paul Bernard et al.
Depression is common with a high risk of relapse/recurrence. There is evidence from multiple randomised controlled trials (RCTs) demonstrating the efficacy of mindfulness-based cognitive therapy (MBCT) for the prevention of depressive relapse/recurrence, and it is included in several national clinical guidelines for this purpose. However, little is known about whether MBCT is being delivered...