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Sarah Byford

12 papers in the library · 819 citations · publishing 2014-2025

Papers

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Examining what works for whom and how in mindfulness-based cognitive therapy (MBCT) for recurrent depression: moderated-mediation analysis in the PREVENT trial.

The British Journal of Psychiatry April 1, 2025 Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al. 4 citations

Personalised management of recurrent depression, considering individual patient characteristics, is crucial. This study evaluates the potentially different mediating role of mindfulness skills in managing recurrent depression using mindfulness-based cognitive therapy (MBCT) among people with varying depression severity. Data from the Prevention of Depressive Relapse or Recurrence (PREVENT)...

DOI: 10.1192/bjp.2024.178 (opens in new tab) Full text (opens in new tab) Recurrent depression Depression severity Mindfulness skills Mindfulness-based cognitive therapy +1

Clinical Effectiveness and Cost-Effectiveness of Supported Mindfulness-Based Cognitive Therapy Self-help Compared With Supported Cognitive Behavioral Therapy Self-help for Adults Experiencing Depression: The Low-Intensity Guided Help Through Mindfulness (LIGHTMind) Randomized Clinical Trial.

JAMA Psychiatry May 1, 2023 Clara Strauss, Anna-Marie Bibby-Jones, Fergal Jones et al.

Depression is prevalent. Treatment guidelines recommend practitioner-supported cognitive behavioral therapy self-help (CBT-SH) for mild to moderate depression in adults; however, dropout rates are high. Alternative approaches are required. To determine if practitioner-supported mindfulness-based cognitive therapy self-help (MBCT-SH) is superior to practitioner-supported CBT-SH at reducing...

Do Adolescents Like School-Based Mindfulness Training? Predictors of Mindfulness Practice and Responsiveness in the MYRIAD Trial

Journal of the American Academy of Child and Adolescent Psychiatry May 1, 2023 Jesus Montero-Marin, Verena Hinze, Catherine Crane et al.

Objective We explored what predicts secondary school students’ mindfulness practice and responsiveness to universal school-based mindfulness training (SBMT), and how students experience SBMT. Method A mixed-methods design was used. Participants were 4,232 students (11-13 years of age), in 43 UK secondary schools, who received universal SBMT (ie, “.b” program), within the MYRIAD trial...

Universal Mindfulness Training in Schools for Adolescents: a Scoping Review and Conceptual Model of Moderators, Mediators, and Implementation Factors

Prevention Science August 1, 2022 Kate Tudor, Shannon Maloney, Anam Raja et al.

There is evidence that universal school-based mindfulness training (SBMT) can have positive effects for young people. However, it is unknown who benefits most from such training, how training exerts effects, and how implementation impacts effects. This study aimed to provide an overview of the evidence on the mediators, moderators, and implementation factors of SBMT, and propose a conceptual...

DOI: 10.1007/s11121-022-01361-9 (opens in new tab) Full text (opens in new tab) Mindfulness School-based programmes Adolescence Universal interventions +4

Effectiveness of universal school-based mindfulness training compared with normal school provision on teacher mental health and school climate: results of the MYRIAD cluster randomised controlled trial.

Evidence-Based Mental Health July 12, 2022 Willem Kuyken, Susan Ball, Catherine Crane et al.

Background: Education is broader than academic teaching. It includes teaching students social-emotional skills both directly and indirectly through a positive school climate. Objective: To evaluate if a universal school-based mindfulness training (SBMT) enhances teacher mental health and school climate. Methods: The My Resilience in Adolescence parallel group, cluster randomised controlled...

The development and internal evaluation of a predictive model to identify for whom Mindfulness-Based Cognitive Therapy (MBCT) offers superior relapse prevention for recurrent depression versus maintenance antidepressant medication

Clinical Psychological Science April 29, 2022 Z. Cohen, R. DeRubeis, Rachel Hayes et al.

Depression is highly recurrent, even following successful pharmacological and/or psychological intervention. We aimed to develop clinical prediction models to inform adults with recurrent depression choosing between antidepressant medication (ADM) maintenance or switching to mindfulness-based cognitive therapy (MBCT). Using previously published data (N = 424), we constructed prognostic models...

Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse

JAMA Psychiatry April 28, 2016 Willem Kuyken, Fiona C Warren, Rod S. Taylor et al. 815 citations

IMPORTANCE: Relapse prevention in recurrent depression is a significant public health problem, and antidepressants are the current first-line treatment approach. Identifying an equally efficacious nonpharmacological intervention would be an important development. OBJECTIVE: To conduct a meta-analysis on individual patient data to examine the efficacy of mindfulness-based cognitive therapy...

DOI: 10.1001/jamapsychiatry.2016.0076 (opens in new tab) Full text (opens in new tab) Psycinfo Mindfulness-based cognitive therapy Medline Randomized controlled trial +4

The effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse/recurrence: results of a randomised controlled trial (the PREVENT study).

Health technology assessment September 2015 Willem Kuyken, Rachel Hayes, Barbara Barrett et al.

Individuals with a history of recurrent depression have a high risk of repeated depressive relapse/recurrence. Maintenance antidepressant medication (m-ADM) for at least 2 years is the current recommended treatment, but many individuals are interested in alternatives to m-ADM. Mindfulness-based cognitive therapy (MBCT) has been shown to reduce the risk of relapse/recurrence compared with usual...

Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial

The Lancet July 4, 2015 Willem Kuyken, Rachel Hayes, B. Barrett et al.

BACKGROUND Individuals with a history of recurrent depression have a high risk of repeated depressive relapse or recurrence. Maintenance antidepressants for at least 2 years is the current recommended treatment, but many individuals are interested in alternatives to medication. Mindfulness-based cognitive therapy (MBCT) has been shown to reduce risk of relapse or recurrence compared with usual...

Update to the study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment depressive relapse/recurrence: the PREVENT trial.

Trials June 10, 2014 Willem Kuyken, Sarah Byford, Richard Byng et al.

Background: Depression is a common and distressing mental health problem that is responsible for significant individual disability and cost to society. Medication and psychological therapies are effective for treating depression and maintenance anti-depressants (m-ADM) can prevent relapse. However, individuals with depression often express a wish for psychological help that can help them...

Low-Intensity Guided Help Through Mindfulness (LIGHTMIND): Study protocol for a randomised controlled trial comparing supported Mindfulness-Based Cognitive Therapy self-help to supported Cognitive Behavioural Therapy self-help for adults experiencing depression

Clara Strauss, Amy Arbon, Michael Barkham et al. preprint

Abstract Background Depression has serious personal, family and economic consequences. It is estimated that it will cost £12.15 billion to the economy each year in England by 2026. Improving Access to Psychological Therapies (IAPT) is the National Health Service talking therapies service in England for adults experiencing anxiety or depression. Over 1 million people are referred to IAPT every...

Examining What Works for Whom and How in Mindfulness-Based Cognitive Therapy (MBCT) for Recurrent Depression: A Moderated-Mediation Analysis in the PREVENT Trial (in press)

Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al. preprint

Background: Personalized management of recurrent depression, considering individual patient characteristics, is crucial. Aims: This study evaluates the potentially different mediating role of mindfulness skills in managing recurrent depression using mindfulness-based cognitive therapy (MBCT) among patients with varying depression severity. Method: Data from the PREVENT trial, comparing MBCT...