International Immunopharmacology
August 1, 2026
Jinghua Zhao, Ruxin Zhang, Jiarui Pan et al.
Depression-like behavior is closely associated with neuroinflammation. Lipopolysaccharide (LPS) can activate N-methyl-d-aspartate receptors and induce cellular pyroptosis and neuroinflammation, thereby triggering depression-like behavior in animals. The ketamine metabolite (2R,6R)-hydroxynorketamine (HNK) exerts significant antidepressant-like effects without the adverse effects associated with...
Psychology of Sport And Exercise
July 1, 2025
Wei Wang, Matthew J. Schweickle, Karin Hägglund et al.
2 citations
Mindfulness can play a critical role in promoting and protecting mental wellbeing among elite athletes. However, mechanisms of change are needed to provide theoretical insight when designing mindfulness-based programs in this population. The purpose of this study was to explore how mindfulness predicts mental wellbeing through the attitudes of gratitude (toward pleasant moments) and...
Engineering Proceedings
March 26, 2025
Wei Wang, Pauline van Dongen, Daria Casciani
This research explores the potential of clothing as a medium for enhancing mindfulness experiences, focusing on the Mysa shirt, a product being developed by the newly founded start-up Touchwaves BV, which integrates haptic technology for breath guidance. Through a user-centered design (UCD) approach, the study focused on the Mysa shirt’s redesign and its use during mindfulness practices. From...
PLoS One
2025
Wei Wang, Dan Wang, Li Liu et al.
3 citations
The widespread use of illegal drugs and their associated problems have emerged as a significant public health concern. This study was conducted to estimate the consumption and prevalence of substance use in selected cities of Guangdong Province through wastewater-based epidemiology. We collected influent wastewater samples from 67 wastewater treatment plants across four cities of Guangdong from...
bioRxiv (Cold Spring Harbor Laboratory)
September 26, 2023
Yi-Ting Chiu, Wei Wang, Pierre Llorach et al.
15 citations
preprint
ABSTRACT Psychedelic drugs like lysergic acid diethylamide (LSD) and psilocybin have emerged as potentially transformative therapeutics for many neuropsychiatric diseases, including depression, anxiety, post-traumatic stress disorder, migraine, and cluster headaches. LSD and psilocybin exert their psychedelic effects via activation of the 5-hydroxytryptamine 2A receptor (HTR2A). Here we provide...
BJPsych Open
July 1, 2023
Muhammad Ishrat Husain, Nicole Ledwos, Elise Fellows et al.
41 citations
Background Randomised controlled trials (RCTs) of psilocybin have reported large antidepressant effects in adults with major depressive disorder and treatment-resistant depression (TRD). Given psilocybin's psychedelic effects, all published studies have included psychological support. These effects depend on serotonin 2A (5-HT2A) receptor activation, which can be blocked by 5-HT2A receptor...
Journal of Affective Disorders
February 1, 2022
Jianyu Que, Le Shi, Wei Yan et al.
Background Trauma experience increases the risk of suicidal ideation, but little is known about potentially psychological mechanisms underlying this relationship. This study aims to examine the relationship between coronavirus disease 2019 (COVID-19)-related traumatic event (CTE) exposure and suicidal ideation among hospital workers, and identify mediating roles of sleep disturbances in this...
Sage Open
April 1, 2021
Chu Wang, Jiayao Xu, Mufan Wang et al.
7 citations
Nightmares influence the mental health of university students, but the prevalence of nightmare and nightmare disorder requires additional documentation. The data of detailed nightmare experience of nightmare disorder and related depressive mood in this population are also scarce. First, a total of 1,451 students in a comprehensive Chinese university were invited to report their nightmare...
Bulletin of the Menninger Clinic
September 1, 2020
Xu Shao, Chu Wang, Chanchan Shen et al.
1 citation
Nightmares are prevalent in psychiatric disorders, and personality disorder features might be associated with nightmare experience, especially in nightmare disorder patients. The authors invited 219 healthy volunteers and 118 nightmare disorder patients to undergo tests of the Nightmare Experience Questionnaire (NEQ), the Parker Personality Measure (PERM), and the Plutchik-van Praag Depression...
Behavioural Brain Research
May 1, 2019
Wei Wang, Le Liu, Xiu Yang et al.
HighlightsSusceptible mice showed depressive‐like behaviors upon chronic social defeat stress.Plasma corticosterone concentration might predict susceptibility to chronic stress.Abnormal glucocorticoid receptor expression was associated with susceptibility.Ketamine exerted antidepressant effect via normalizing HPA axis response. &NA; Chronic stress is an important factor for depression. Most...
Journal of Psychiatry
2017
Wei Wang, Jiawei Wang
Nightmares are typically extended, elaborate dream narratives, and usually occur during rapid eye movement period of sleep.Nightmare experience is accompanied by the disturbed affect culminating in arousal, which usually involves an individual's efforts to avoid threats to survival, security, or physical integrity, but often results in awakening with rapid orientation and alertness...
Psychiatry and Clinical Neurosciences
December 1, 2016
Chanchan Shen, Jiawei Wang, Guorong Ma et al.
The purpose of the current study was to explore the cerebral areas involved in nightmare disorder. Fifteen nightmare disorder patients and 15 healthy volunteers were invited to undergo resting-state functional magnetic resonance imaging and to complete the Nightmare Experience Questionnaire. The nightmare disorder patients scored higher on the Physical Effect and Horrible Stimulation scales,...
September 30, 2014
Wanzhen Chen, You Xu, Ming Zhu et al.
Background: Nightmare experience is associated with a broad spectrum of psychopathology, however, there lacks a structure-validated questionnaire to measure the effects of nightmare contents on the physical, psychological and behavioral aspects. Methods: Based on the clinical manifestation and previous documentation, we have designed a matrix of 95 items to measure the nightmare contents, plus...