Cell
August 1, 2026
Yating Wen, Lingjie Tang, Wenwen Duan et al.
Cancer remains a leading cause of morbidity and mortality worldwide. While classical psychedelics have been used clinically to treat cancer-associated psychiatric disorders, their impact on tumor progression is unclear. Here, we show that by targeting the serotonin receptor 5-HT2AR, lysergic acid diethylamide (LSD) enhances CD8+ T cell-mediated antitumor immunity and suppresses colorectal...
Behavioral Sciences
July 6, 2026
Chenguang Zhao, Yifei Sun, Wei Zhang
Background: This study compared the effects of mindfulness training (MT) and cognitive-behavioral training (CBT) on ADHD symptoms, test anxiety, and self-concept in children with ADHD and explored potential pathways of change associated with the two interventions. Methods: After a two-stage screening and eligibility confirmation procedure, 63 children with ADHD were included in the final...
Pharmacological Research
July 1, 2026
Yang Zhou, Wanchen Sun, Yuxuan Fu et al.
Perioperative depressive symptoms (PDSs) are common among patients who undergo major surgery and can lead to worse clinical outcomes. Esketamine has been reported to alleviate PDSs in patients undergoing certain types of surgery. However, there is a lack of evidence from large-scale, multisurgery studies to support its therapeutic effects in individuals with preexisting moderate-to-severe PDSs....
Current gastroenterology reports
November 19, 2025
Wei Zhang, Soo Young Hwang, Jay Luther
1 citation
Alcohol use disorder (AUD) drives alcohol-associated liver disease (ALD), and relapsing after abstinence remains a significant challenge before and after transplantation. This review summarizes evidence for pharmacotherapies in relapse prevention and their integration into ALD care. Naltrexone and acamprosate reduce the relapse in the general AUD population, though data in ALD are limited....
Iranian journal of public health
April 1, 2024
Wei Guofang, Wei Zhang, Zhen Zhu
COVID-19 infection is transmitted easily and quickly, exposing medical care workers, especially nursing workers, to tremendous stress. Therefore, identifying the factors influencing the sleep quality of nurses and implementing corresponding interventions are conducive to improving the sleep quality of nurses and enhancing their nursing quality. Form September to December 2022, a survey-based...
Frontiers in Psychiatry
February 15, 2024
Shuping Fang, Xin Yang, Wei Zhang
21 citations
Introduction Psilocybin is a classic psychedelics, which has been shown to have antidepressant effects by many studies in recent years. In this study, we aim to evaluate the efficacy, acceptability and tolerability of psilocybin in the treatment of primary (major depressive disorder) or secondary (experiencing distress related to life-threatening diagnoses and terminal illness) depression....