Aim/objective: To systematically assess the effectiveness of mindfulness-based interventions (MBIs) in reducing psychological stress and anxiety among undergraduate nursing students, and to explore possible moderators of intervention outcomes. Background: Nursing students are exposed to high levels of psychological stress and anxiety, which can impact their well-being and academic success. MBIs...
Abstract: Objectives: Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes, with neuropathic pain and sensory abnormalities severely affecting patients’ quality of life. Current pharmacological treatments have limitations including insufficient efficacy and adverse reactions. Mindfulness-based interventions (MBIs) show potential in chronic pain management, yet their...
The integration of artificial intelligence (AI) into athletic training is accelerating, yet its psychological implications for athletes remain insufficiently understood. Drawing on the transactional model of stress and the stress-buffering framework of mindfulness, this study examined whether mindfulness training can mitigate adverse psychological responses associated with AI-assisted training....
Cancer remains a leading cause of morbidity and mortality worldwide. While classical psychedelics have been used clinically to treat cancer-associated psychiatric disorders, their impact on tumor progression is unclear. Here, we show that by targeting the serotonin receptor 5-HT2AR, lysergic acid diethylamide (LSD) enhances CD8+ T cell-mediated antitumor immunity and suppresses colorectal...
Background: This study compared the effects of mindfulness training (MT) and cognitive-behavioral training (CBT) on ADHD symptoms, test anxiety, and self-concept in children with ADHD and explored potential pathways of change associated with the two interventions. Methods: After a two-stage screening and eligibility confirmation procedure, 63 children with ADHD were included in the final...
Perioperative depressive symptoms (PDSs) are common among patients who undergo major surgery and can lead to worse clinical outcomes. Esketamine has been reported to alleviate PDSs in patients undergoing certain types of surgery. However, there is a lack of evidence from large-scale, multisurgery studies to support its therapeutic effects in individuals with preexisting moderate-to-severe PDSs....
BMC Public HealthFebruary 13, 2026Yanhui Mao, Yiyan Li, Shujun Wang et al.
BACKGROUND: University students experience insomnia at rates higher than those of other age groups, creating significant challenges to their physical and mental health, as well as their academic achievements. While recent research has highlighted the potential of mindfulness to improve sleep quality, the mechanisms through which mindfulness alleviates insomnia remained understudied. Pain...
Alcohol use disorder (AUD) drives alcohol-associated liver disease (ALD), and relapsing after abstinence remains a significant challenge before and after transplantation. This review summarizes evidence for pharmacotherapies in relapse prevention and their integration into ALD care. Naltrexone and acamprosate reduce the relapse in the general AUD population, though data in ALD are limited....
Test anxiety not only affects the performance of high school students in exams but also impacts their mental health. Previous studies have found that mindfulness helps alleviate the negative effects of test anxiety, but studies on its underlying mechanisms remain relatively scarce. Based on the Process Model of Emotion Regulation and the Conservation of Resources Theory, this study investigates...
BACKGROUND Neuropsychiatric symptoms (NPS) in mild cognitive impairment (MCI) are associated with accelerated Alzheimer's disease (AD) progression. Identifying multimodal brain imaging patterns associated with NPS in MCI may help understand pathophysiology correlates AD. METHODS This cross-sectional resting-state functional magnetic resonance imaging study included 376 participants: 130 MCI...
Ketamine is a quick acting antidepressant drug, and an accurate detection method is lacking. Ketamine's effects in a rat depression model have not previously been well explored using glutamate chemical exchange saturation transfer (GluCEST). To investigate the GluCEST changes of chronic unpredictable mild stress (CUMS) rats after receiving either ketamine or saline injection. Randomized animal...
COVID-19 infection is transmitted easily and quickly, exposing medical care workers, especially nursing workers, to tremendous stress. Therefore, identifying the factors influencing the sleep quality of nurses and implementing corresponding interventions are conducive to improving the sleep quality of nurses and enhancing their nursing quality. Form September to December 2022, a survey-based...
Introduction Psilocybin is a classic psychedelics, which has been shown to have antidepressant effects by many studies in recent years. In this study, we aim to evaluate the efficacy, acceptability and tolerability of psilocybin in the treatment of primary (major depressive disorder) or secondary (experiencing distress related to life-threatening diagnoses and terminal illness) depression....
Repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) has been shown to reduce cravings in heroin-dependent (HD) individuals, but the mechanisms underlying the anti-craving effects of rTMS are unknown. Abnormalities in the default mode network (DMN) are known to be consistent findings in HD individuals and are involved in cravings. We assessed...
Claustrophobia is a psychological disease. It is estimated to occur in 2.1-14.3% of all magnetic resonance imaging (MRI) examinations. Mindfulness decompression is an effective means to treat and reduce fear and anxiety. There is a rare report on the application of mindfulness-based stress reduction therapy in the magnetic resonance examinations of patients with claustrophobia to date. The...
R mRNA in the mPFC was significantly decreased to 5-Hydroxytryptamine7 (5-HT7) receptors in the medial prefrontal cortex (mPFC) play a critical role in complex cognitive impairment in schizophrenia. The mouse model of schizophrenia was established through the neonatal administration of phencyclidine (nPCP). Recombinant adeno-associated virus-mediated gene knockdown was used to investigate the...
Kahn and Hobson (1993) proposed that dreams are a product of self-organization of brain during sleep.As a complex system far from equilibrium state, the dreaming brain may form a new pattern by the interaction between components within this system.At REM sleep stage, signals from neuronal clusters self-organize and form image fragments, then the image fragments interact and produce images, and...