Cell ReportsJuly 24, 2026Viktor J Oláh, Isabelle F Witteveen, Tue G Banke et al.
GABAergic inhibitory interneurons balance brain activity by suppressing excessive excitatory signaling and shaping network oscillations. Despite this critical function, our understanding of how neural circuits regulate GABAergic systems remains limited. Although N-methyl-D-aspartate receptor (NMDAR) functionality is defined by the GluN2A-D subunits, the interneuron NMDAR subunit composition...
Schizophrenia is associated with marked abnormalities in consciousness, specifically in the interplay between implicit and explicit cognitive processing.However, whether these deficits originate from early sensory degradation or late-stage access failures remains heavily debated.This narrative review synthesizes psychophysical, electrophysiological, and neuroimaging literature to evaluate these...
SLEEPJMay 8, 2026Jing Zhang, Andres Pena, Negin Sattari Barabadi et al.
Abstract Introduction Sleep supports emotion regulation by preferentially consolidating emotional memories while attenuating reactivity. We have shown that dream recall plays an active role by increasing negative over neutral memories and reducing reactivity. In women, fluctuating reproductive hormones across the menstrual cycle influence sleep features implicated in emotional memory, yet...
Coronary heart disease (CHD) often coexists with mood disorders (MDs), but research on comorbidity predictors and interventions remains limited. This two‑phase mixed‑methods study enrolled 390 CHD patients diagnosed by coronary angiography. Mood disorders were screened using the HAMD (≥7) and confirmed via DSM‑5 psychiatric evaluation. In the observational phase, 219 CHD patients with MDs and...
Employees' environmentally sustainable work behavior is a critical enabler of organizational sustainable development. While prior research has primarily focused on either organizational motivators or individual attributes influencing sustainable work behavior, this study integrates these perspectives to provide a more nuanced and holistic understanding. Drawing on values–attitudes–behavior and...
Magneto/electroencephalography (M/EEG) studies of dreaming are an essential paradigm in the investigation of neurocognitive processes of human consciousness during sleep, but they are limited by the number of observations that can be collected per study. Dream research also involves substantial methodological and conceptual variability, which poses problems for the integration of results. To...
To investigate the effect of intraoperative low-dose esketamine administered at anesthesia induction on postoperative quality of recovery in total laparoscopic hysterectomy. One-hundred six female patients scheduled for elective total laparoscopic hysterectomy were randomly divided into saline group (group P) and esketamine group (group S). Group P received induction with normal saline,...
Dreaming is a universal human behavior that has inspired searches for meaning across many disciplines including art, psychology, religion, and politics, yet its function remains poorly understood. Given the suggested role of sleep in emotional memory processing, we investigated whether reported overnight dreaming and dream content are associated with sleep-dependent changes in emotional memory...
IntroductionAltered functional connectivity of resting-state functional magnetic resonance imaging (rs-fMRI) within default mode network (DMN) regions has been verified to be closely associated with cognitive decline in patients with Type 2 diabetes mellitus (T2DM), but most studies neglected the fluctuations of brain activities—the dynamic effective connectivity (DEC) within DMN of T2DM is...
Parents of children with cancer may experience persistent psychological distress and impaired physical health throughout their children's diagnosis and treatment. This study aimed to develop a mindful self-compassion program for parents of children with cancer and explore its effect. This pre-post-test study without a control group was conducted with 34 Chinese parents of children with cancer,...
Magneto/electroencephalography (M/EEG) studies of dreaming are an essential paradigm in the investigation of neurocognitive processes of human consciousness during sleep, but they are limited by the number of observations that can be collected per study. Dream research also involves substantial methodological and conceptual variability, which poses problems for the integration of results. To...
bioRxiv Preprint ServerApril 12, 2023Malika S. Datta, Yannan Chen, Shradha Chauhan et al.6 citations
preprint
Ketamine is a multifunctional drug with clinical applications as an anesthetic, as a pain management medication and as a transformative fast-acting antidepressant. It is also abused as a recreational drug due to its dissociative property. Recent studies in rodents are revealing the neuronal mechanisms that mediate the complex actions of ketamine, however, its long-term impact due to prolonged...
BackgroundPromoting reflection about death may support better living, and how to carry out death education is an important issue to be addressed across the world. The purpose of the current study was to explore the attitude of heart transplant recipients toward death and their inner real experience to provide information for the development of death education strategies.MethodsA...
We aimed to evaluate the efficacy of an enhanced mindfulness based stress reduction (MBSR+) versus stress management for headache (SMH). We performed a randomized, assessor-blind, clinical trial of 98 adults with episodic migraine recruited at a single academic center comparing MBSR+ (n=50) to SMH (n=48). MBSR+ and SMH were delivered weekly by group for 8 weeks, then bi-weekly for another 8...
The stream of human consciousness persists during sleep, albeit in altered form. Disconnected from external input, the mind and brain remain active, at times creating the bizarre sequences of thought and imagery that comprise "dreaming." Yet despite substantial effort toward understanding this unique state of consciousness, no reliable neurophysiological indicator of dreaming has been...
This study examined mood enhancement effects from 4-week focusing attention (FA) meditation and 4-week open monitoring (OM) meditation in an 8-week mindfulness training program designed for ordinary individuals. Forty participants were randomly assigned to a training group or a control group. All participants were asked to perform cognitive tasks and subjective scale tests at three time points...
NeuronNovember 7, 2018Bo Liang, Lifeng Zhang, Giovanni Barbera et al.
The medial prefrontal cortex (mPFC) is important for social behavior, but the mechanisms by which mPFC neurons code real-time social exploration remain largely unknown. Here we utilized miniScopes to record calcium activities from hundreds of excitatory neurons in the mPFC while mice freely explored restrained social targets in the absence or presence of the psychedelic drug phencyclidine...
According to whether it is extended in time, self can be divided into two important parts—— minimal self and narrative self. Embodied constructivism holds the idea that distinguishing self from non-self is the core concept of minimal self. Therefore, defending the construction theory of self should emphasize the importance of the body itself. According to pathology and illusion studies of...