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LSD: all studies

Page 93 of 282: studies 921 to 930 of 2,815, newest first. Back to the LSD overview

Research

Psychopathology and Psychophysiology of Minimal LSD-25 Dosage

A M A Archives of Neurology & Psychiatry February 1, 1958 Theodore Greiner 47 citations

Despite 14 years of investigation, as intensive as accorded any biologically active chemical, a gap remains in the systematic description of human response to lysergic acid diethylamide (LSD-25). The dramatic schizophrenic-like symptoms after doses of 40μg to 100μg have drawn the main interest. The threshold for activity is placed at 20μg by general consensus, while perfunctory administration...

The Pharmacology of Mescaline and D-Lysergic Acid Diethylamide (LSD)

New England Journal of Medicine January 2, 1958 George B. Koelle 18 citations

DURING the last few years a great revival of interest has occurred in the search for a biochemical basis for schizophrenia and the other types of psychosis. There are several reasons for this. Modern laboratory technics permit the detection and accurate quantitation of substances in the blood and tissues for which satisfactory procedures were not available formerly. The discovery of a partially...

DOI: 10.1056/nejm195801022580106 (opens in new tab) Mescaline Lysergic acid diethylamide Schizophrenia object-oriented programming Mental disease +4

THE EFFECT OF LSD AND RESERPINE ON THE CENTRAL NERVOUS SYSTEM OF THE CAT

The Japanese Journal of Pharmacology 1958 Hiroshi Takagi, Shigeru Yamamoto, Shuji Takaori et al. 11 citations

In 1943 in Switzerland, A. Hofmann (1) working on the synthesis of lysergic acid diethylamide (LSD-25), a common fragment of ergot alkaloids, noticed the peculiar sensation of vertigo and restlessness. Thenceforce it was reported by Stoll et al. (1, 2), Forrer et al. (3) and Rinkel et al. (4) that a small dose of LSD caused predominantly schizophrenic symptoms that were manifested in...

The effect of lysergic acid diethylamide, 5-hydroxytryptamine, and related compounds on the liver fluke, Fasciola hepatica

British Journal of Pharmacology and Chemotherapy December 1, 1957 T. E. Mansour 51 citations

The rhythmical activity of the liver fluke, Fasciola hepatica, was stimulated by 5-hydroxytryptamine and by lysergic acid diethylamide at very low concentrations. The effect was peripheral and was not mediated through the central ganglion. Other amines also stimulated rhythmical activity, the most potent being the indolamines.Bromolysergic acid diethylamide, and other analogues such as...

Psychopharmacological Studies of Lysergic Acid Diethylamide (LSD-25) Intoxication

A M A Archives of Neurology & Psychiatry December 1, 1957 Lincoln D. Clark 19 citations

One consequence of the recent interest in psychotomimetic drugs has been a search for pharmacological agents that will "block" drug-induced psychological disturbances and hallucinations. Fabing1reported that azacyclonol (Frenquel) in small doses prevented the occurrence of lysergic acid diethylamide (LSD-25) "psychoses" in man, although one of us (L. D. C.) was unable to verify this...

Pharmacology of Lysergic Acid Diethylamide and Some of Its Related CompoundS

Journal of Pharmacy and Pharmacology September 1, 1957 E Rothlin 64 citations

Journal Article Pharmacology of Lysergic Acid Diethylamide and Some of Its Related CompoundS Get access E Rothlin E Rothlin Professor of the University of Basle, Sonnenweg 6, Basle Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 9, Issue 1, September 1957, Pages 569–587, https://doi.org/10.1111/j.2042-7158.1957.tb12312.x...

THE PRESERVATION OF SUBSTANCE P BY LYSERGIC ACID DIETHYLAMIDE

British Journal of Pharmacology and Chemotherapy September 1, 1957 William A. Krivoy 23 citations

Lysergic acid diethylamide (LSD) potentiated the response of guinea‐pig ileum to substance P but not to histamine. It also inhibited the disappearance of substance P when incubated with guinea‐pig brain extract but not when incubated with chymotrypsin. Eserine, morphine, mescaline, chlorpromazine, ergometrine, strychnine and 2 bromo‐LSD did not have this effect. Oxytocin was not destroyed by...

Effects of Lysergic Acid Diethylamide (LSD) on the Time Sense of Normals

A M A Archives of Neurology & Psychiatry September 1, 1957 William K. Boardman 21 citations

Introduction Much of the interest in lysergic acid diethylamide (LSD) is due to its capacity to produce schizophrenic-like behavior when administered in extremely small quantities. 4,6 Among the reported changes resulting from LSD have been alterations in time perception. DeShon, Rinkel, and Solomon, 1 found changes in the form of experiences of acceleration, retardation, or nonexistence of...

DOI: 10.1001/archneurpsyc.1957.02330390103013 (opens in new tab) Lysergic acid diethylamide Schizophrenia object-oriented programming Time perception Audiology +3