In 1943 in Switzerland, A. Hofmann (1) working on the synthesis of lysergic acid diethylamide (LSD-25), a common fragment of ergot alkaloids, noticed the peculiar sensation of vertigo and restlessness. Thenceforce it was reported by Stoll et al. (1, 2), Forrer et al. (3) and Rinkel et al. (4) that a small dose of LSD caused predominantly schizophrenic symptoms that were manifested in...