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LSD: all studies

Page 91 of 282: studies 901 to 910 of 2,815, newest first. Back to the LSD overview

Research

Effects on homeostasis of 5-hydroxytryptamine, lysergic acid diethylamide and 2-brom-d-lysergic acid

American Journal of Physiology-Legacy Content December 1, 1959 J. Paul Mcneill, John K. Hampton 3 citations

Rats were injected intramuscularly with 5-HT or LSD and intravenously with 5-HT, LSD, BOL or equimolar concentrations of 5-HT + LSD or 5-HT + BOL. Appropriate saline controls were included. They were then exposed to a standard amount of Noble-Collip trauma. Animals receiving 5-HT i.m. showed a significant multiphasic mortality curve after trauma depending on dose of drug. With small doses,...

Influence of Lysergic Acid Diethylamide (LSD-25) on Subjective Time

Archives of General Psychiatry November 1, 1959 H. Aronson 32 citations

Introduction Various reports1,14have shown that the subjective sense of time can be considerably altered through changes in the external circumstances under which the judgment is made. Somewhat less is known of the influence of the subject’s physical state on his ability to estimate time. This lack may be at least partially due to the fact that most conditions, such as fever or delirium, which...

Behavioral Effects of Lysergic Acid Diethylamide (LSD-25)

A M A Archives of General Psychiatry October 1, 1959 Seymour Wapner 12 citations

The behavioral effects of lysergic acid diethylamide (LSD-25) have been studied programmatically in the Clark Laboratories, utilizing the framework of organismic and developmental theory. In the course of testing some of the implications of these theoretical positions, a number of situations have been developed to study space localization. This paper involves the situation dealing with the...

DOI: 10.1001/archpsyc.1959.03590040087008 (opens in new tab) Lysergic acid diethylamide Space punctuation Developmental psychology Biochemistry

Acquired and Crossed Tolerance to Mescaline, LSD-25, and BOL-148

Archives of General Psychiatry September 1, 1959 Antonio Balestrieri 76 citations

It has been demonstrated experimentally that tolerance to the effects of lysergic acid diethylamide (LSD-25) develops rapidly, both in man1,4,6and in animals.5Tolerance to mescaline, with a less rapid development, was observed in rats by Freedman et al.5We are not aware of studies on tolerance to 2-bromo-d-lysergic acid diethylamide (BOL-148). Tachyphylaxis to LSD-25, it seems, is another...

Comparison of the LSD-25 Experience and Delirium Tremens

Archives of General Psychiatry July 1, 1959 Keith S. Ditman 21 citations

Introduction Recently psychiatry has had a renewed interest in drugs with “hallucinogenic” properties. New ones are being made, or extracted from plants, at a rapid rate. These drugs are being used more and more widely in treatment and in psychodynamic investigations. We are struck by the many claims that have been made about these psychopharmacological agents and, in particular, have noted the...

Influence of LSD-25 on optically evoked potentials in the nonanesthetized rabbit

American Journal of Physiology-Legacy Content June 1, 1959 Werner P. Koella, C.h. Wells 12 citations

The influence of LSD-25 (i.v.) upon the optically evoked cortical potentials was studied in chronically prepared unanesthetized and noncurarized rabbits over a 23-hour period. With moderate doses of the drug (35 µg/animal) the potentials were enhanced for a period of over 6 hours. The time course of the amplitudes indicates a triphasic pattern. LSD-25 reduced the latency of the potentials by...

DOI: 10.1152/ajplegacy.1959.196.6.1181 (opens in new tab) Latency audio Rabbit cipher Anesthesia Pharmacology

Use of Lysergic Acid Diethylamide in a Psychotherapeutic Setting

Archives of Neurology And Psychiatry May 1, 1959 Sidney Cohen 49 citations

In experimental psychiatry the hallucinogenic drugs have a firmly established position; hundreds of articles attest to the growing interest in their psychotomimetic activity. As an adjunct to psychotherapy, however, their potential has been incompletely investigated. The initial mention of lysergic acid diethylamide (LSD-25) in this connection appears to be the 1950 publication by Busch and...