The Pharmacology of Mescaline and D-Lysergic Acid Diethylamide (LSD)
New England Journal of Medicine January 2, 1958 DOI: 10.1056/nejm195801022580106 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | LSD Mescaline |
| Keywords | Schizophrenia object-oriented programming Mental disease Psychosis Freudian slip Hallucinogen Psychotherapist |
| Citations | 18 |
| Key findings | Advances in laboratory methods and the biochemical defect found in phenylketonuria have renewed the search for a biochemical basis for schizophrenia and other psychoses. |
Abstract
DURING the last few years a great revival of interest has occurred in the search for a biochemical basis for schizophrenia and the other types of psychosis. There are several reasons for this. Modern laboratory technics permit the detection and accurate quantitation of substances in the blood and tissues for which satisfactory procedures were not available formerly. The discovery of a partially correctable biochemical defect in one type of mental deficiency, phenylketonuria,1 has encouraged the hope that other forms of mental disease may be explained in similar terms. Many investigators believe that the Freudian concepts, with their emphasis on the . . .
Comparable studies
Other narrative reviews on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Study of a New Schizophrenomimetic Drug—Sernyl | 1959 | Review | |
| Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways | 2017 | Review | |
| Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine | 2020 | Review | |
| Legal highs: staying on top of the flood of novel psychoactive substances | 2015 | Review | |
| Psychedelic Drugs in Biomedicine | 2017 | Review |
Citations in the library
Cited by 3
- Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects Biological Psychiatry November 29, 2014
- Dark Classics in Chemical Neuroscience: Mescaline ACS Chemical Neuroscience May 30, 2018
- The epidemiology of mescaline use: Pattern of use, motivations for consumption, and perceived consequences, benefits, and acute and enduring subjective effects. Journal of Psychopharmacology March 1, 2022
Cites 16
- Schizophrenia: A New Approach. II. Result of a Year's Research Journal of Mental Science 1954
- The Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Journal of Mental Science April 1, 1954
- LYSERGIC ACID DIETHYLAMIDE (LSD-25) American Journal of Psychiatry June 1, 1952
- EFFECTS OF MESCALINE AND LYSERGIC ACID (d-LSD-25) American Journal of Psychiatry February 1, 1952
- Studies on Lysergic Acid Diethylamide (LSD-25) A M A Archives of Neurology & Psychiatry November 1, 1956
and 11 more in the library