Production of Cross-Tolerance to Psychosis-Producing Doses of Lysergic Acid Diethylamide and Psilocybin
Harold A. Abramson, Anabela P. Rolo, B. Sklarofsky, J. Stache
The Journal of Psychology 1960 DOI: 10.1080/00223980.1960.9916396 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Interventions | Lysergic acid diethylamide Psilocybin |
| Topics | LSD Psilocybin |
| Keywords | Psychosis Hallucinogen |
| Citations | 22 |
| Key findings | Cross-tolerance between LSD and psilocybin indicates they likely produce psychosis through a shared mechanism. |
Abstract
(1960). Production of Cross-Tolerance to Psychosis-Producing Doses of Lysergic Acid Diethylamide and Psilocybin. The Journal of Psychology: Vol. 49, No. 1, pp. 151-154.
Comparable studies
Other experimental studies on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Neural correlates of the LSD experience revealed by multimodal neuroimaging. Human participants | 2016 | Experimental study | |
| Crystal structure of an LSD-bound human serotonin receptor | 2017 | Experimental study with structural biology and molecular dynamics simulations | |
| Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe Midbrain neurons containing serotonin | 1968 | Experimental study | |
| Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD. Human brain | 2017 | Experimental study | |
| LSD-Assisted Psychotherapy in Patients with Terminal Cancer Cancer patients | 1973 | Experimental study | n = 60 |
Citations in the library
Cited by 8
- Differential tolerance to biological and subjective effects of four closely spaced doses of N,N-dimethyltryptamine in humans Biological Psychiatry May 1, 1996
- Hallucinogenic Drugs in Psychiatric Research and Treatment Perspectives and Prospects The Journal of Nervous and Mental Disease March 1, 1995
- Psychosis and psychedelics: Historical entanglements and contemporary contrasts. Transcultural Psychiatry October 1, 2022
- Psilocybin as a discriminative stimulus: Lack of specificity in an animal behavior model for ?hallucinogens? Psychopharmacology February 1, 1982
- Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics. Frontiers in Psychiatry November 6, 2024
and 3 more in the library