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Werner P. Koella

1 paper in the library · 12 citations · publishing 1959

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Influence of LSD-25 on optically evoked potentials in the nonanesthetized rabbit

American Journal of Physiology-Legacy Content June 1, 1959 Werner P. Koella, C.h. Wells 12 citations

The influence of LSD-25 (i.v.) upon the optically evoked cortical potentials was studied in chronically prepared unanesthetized and noncurarized rabbits over a 23-hour period. With moderate doses of the drug (35 µg/animal) the potentials were enhanced for a period of over 6 hours. The time course of the amplitudes indicates a triphasic pattern. LSD-25 reduced the latency of the potentials by...