Saúde e PesquisaDecember 31, 2015Bruno Acharezzi, Gabriela Carolina Tangerino, Gabriel Sperandio Milan et al.4 citations
Introdução: O chá de Ayahuasca geralmente é utilizado para alcançar o êxtase da experiência espiritual dentro do contexto do xamanismo. Seu preparo se dá com a maceração do cipó da Banisteropsis caapi com as folhas da Psycotria viridis. O efeito ocorre pela metabolização do chá no fígado e intestino delgado, aumentando o nível de serotonina no organismo. Métodos: Utilizaram-se ratos Wistar...
Ayahuasca is a hallucinogenic beverage that combines the action of the 5-HT2A/2C agonist N,N-dimethyltryptamine (DMT) from Psychotria viridis with the monoamine oxidase inhibitors (MAOIs) induced by beta-carbonyls from Banisteriopsis caapi. Previous investigations have highlighted the involvement of ayahuasca with the activation of brain regions known to be involved with episodic memory,...
Henri Acselrad fala sobre um duplo movimento presente nas religioes de matriz africana, tanto “de invencao” quanto “de heranca”, que faz com que um “exercicio de memoria” seja simul-taneamente “capaz de animar dinâmicas de transformacao” (:21). Fruto de em-preendimento coletivo de consideravel porte – evidenciado nos agradecimentos que incluem academicos, religiosos, membros do poder publico –...
Ayahuasca is an Amazonian botanical hallucinogenic brew which contains dimethyltryptamine, a 5-HT2A receptor agonist, and harmine, a monoamine-oxidase A inhibitor. Our group recently reported that ayahuasca administration was associated with fast-acting antidepressive effects in 6 depressive patients. The objective of the present work was to assess the antidepressive potentials of ayahuasca in...
FigshareDecember 3, 2015Ekman Schenberg Eduardo, Felipe Morel Alexandre João, Renato Filev et al.
<p>Concentration (mg/ml) of 13 compounds screened in the <i>Hoasca</i> tea, estimated ingested dose (mg/kg) and total amount ingested of each compound (mg).</p><p>Concentration of chemical compounds in Ayahuasca.</p>
BackgroundAyahuasca is a psychotropic plant tea used for ritual purposes by the indigenous populations of the Amazon. In the last two decades, its use has expanded worldwide. The tea contains the psychedelic 5-HT2A receptor agonist N,N-dimethyltryptamine (DMT), plus β-carboline alkaloids with monoamine-oxidase-inhibiting properties. Acute administration induces an introspective dream-like...
In this thesis, I examine how dividual and individual modes of personhood enable neoshamanic ayahuasca drinkers in Australia to reconfigure cultural ideals and everyday ethical practices. My ethnographic fieldwork allowed me to trace social conventions of drinking ayahuasca, participants’ techniques of the ecstatic body and senses, and narrative styles of codifying ecstatic trance, to determine...
Ayahuasca continues to attract tourists to South America, where there has been a growth in the number of centers offering hallucinogenic ayahuasca experiences. The aims of this study were to (1) discover the reasons foreigners seek this type of experience; (2) define what an ayahuasca experience entails; (3) discover subjective perceptions of ayahuasca's benefits and risks; and (4) describe...
Cluster headache is one of the most debilitating pain syndromes. A significant number of patients are refractory to conventional therapies. The Clusterbusters.org medication use survey sought to characterize the effects of both conventional and alternative medications used in cluster headache. Participants were recruited from cluster headache websites and headache clinics. The final analysis...
Ritual use of ayahuasca, an amazonian Amerindian medicine turned sacrament in syncretic religions in Brazil, is rapidly growing around the world. Because of this internationalization, a comprehensive understanding of the pharmacological mechanisms of action of the brew and the neural correlates of the modified states of consciousness it induces is important. Employing a combination of...
Light microscopical examination of plant and fungal remains in the post mortem gut may be capable of demonstrating the ingestion of unexpected natural psychotropic materials. This is demonstrated here in a case in which a 'shaman' was accused of causing the death of a young man. The deceased had participated in a ceremony which involved the drinking of ayahuasca in order to induce a...
Over the last fifteen years the use of the indigenous Amazonian psychoactive beverage ayahuasca has been reimagined in alternative healing circles of Western countries. This paper explores the practice of ayahuasca neoshamanism in Australia and examines ways in which acts of vomiting and ecstatic trance‐visions involve heightened affective states and moral projects of healing. Aspects of...
Data from EEG recordings and plasma samples from volunteers who took ayahuasca in an experiment aproved and conducted at Federal University of São Paulo. Under review at PLOS ONE
Ayahuasca, a psychoactive beverage used by indigenous and religious groups, is generally prepared by the coction of Psychotria viridis and Banisteriopsis caapi plants containing N,N-dimethyltryptamine (DMT) and β-carboline alkaloids, respectively. To investigate the acute toxicity of ayahuasca, the infusion was administered by gavage to female Wistar rats at doses of 30X and 50X the dose taken...
Ayahuasca is a psychoactive substance from the Amazon rainforest regions of Peru, Colombia, Ecuador, and Brazil. Although its use originated among indigenous tribes in the Amazon basin, it has become increasingly popularized in Western society through the transnational markets of spirituality and religiosity driven by globalization, Postmodernity, and new forms of religious practice. In this...
Ayahuasca is a hallucinogenic brew traditionally used by Northwestern Amazonian indigenous groups for therapeutic purposes. It is prepared by the decoction of Banisteriopsis caapi with the leaves of Psychotria viridis. Banisteriopsis caapi contains β-carbolines that are inhibitors of monoamine oxidase and P. viris is rich in dimethyltryptamine, a 5-HT(1A/2A/2C) agonist. Acute ayahuasca...
There is lack of specificity in the diagnosis of substance-induced mental disorder. The knowledge of the pharmacodynamic properties of ayahuasca consumption allows a more physiopathological approach to the diagnosis of the patient.
The experiences induced by psychedelics share a wide variety of subjective features, related to the complex changes in perception and cognition induced by this class of drugs. A remarkable increase in introspection is at the core of these altered states of consciousness. Self-oriented mental activity has been consistently linked to the Default Mode Network (DMN), a set of brain regions more...
BackgroundHallucinogenic drugs were used to treat alcoholic patients in the past, and recent developments in the study of hallucinogens led to a renewal of interest regarding the application of these drugs in the treatment of addiction. In this scenario, accumulating evidence suggests that the hallucinogenic brew ayahuasca (Aya) may have therapeutic effects on substance abuse problems.MethodsWe...