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Ayahuasca research published in 2012

23 studies whose primary subject is ayahuasca were published in 2012, down from 25 in 2011. Newest first. Back to the ayahuasca overview

Studies

Harmine augments electrically evoked dopamine efflux in the nucleus accumbens shell

Journal of Psychopharmacology October 17, 2012 Daniel I. Brierley, Colin Davidson 42 citations

Harmine is a β-carboline alkaloid and major component of ayahuasca, a traditional South American psychoactive tea with anecdotal efficacy for treatment of cocaine dependence. Harmine is an inhibitor of monoamine oxidase A (MAO-A) and interacts in vitro with several pharmacological targets which modulate dopamine (DA) neurotransmission. In vivo studies have demonstrated dopaminergic effects of...

DOI: 10.1177/0269881112463125 (opens in new tab) Ayahuasca Harmine Nucleus accumbens Pharmacology +3

Contemporary Guarani Shamanisms: “Traditional Medicine” and Discourses of Native Identity in Brazil

Health Culture and Society September 8, 2012 E J Langdon, I S Rose 9 citations

The psychoactive substance known as ayahuasca has long been identified with Amazonian shamanism and traditional medicine. Over the last two decades its use has spread outside this region to urban populations in different parts of the world. This paper examines the adoption of the ritual use of the beverage by the Guarani Indians along the southern coast of Brazil. We argue that this process is...

Personality, Psychopathology, Life Attitudes and Neuropsychological Performance among Ritual Users of Ayahuasca: A Longitudinal Study

PLoS One August 8, 2012 José Carlos Bouso, Débora González, Sabela Fondevila et al. 313 citations

Ayahuasca is an Amazonian psychoactive plant beverage containing the serotonergic 5-HT(2A) agonist N,N-dimethyltryptamine (DMT) and monoamine oxidase-inhibiting alkaloids (harmine, harmaline and tetrahydroharmine) that render it orally active. Ayahuasca ingestion is a central feature in several Brazilian syncretic churches that have expanded their activities to urban Brazil, Europe and North...

DOI: 10.1371/journal.pone.0042421 (opens in new tab) Ayahuasca Psychopathology Hallucinogen Impulsivity +2

Enhancement of Creative Expression and Entoptic Phenomena as After-Effects of Repeated Ayahuasca Ceremonies

Journal of Psychoactive Drugs July 1, 2012 Ede Frecska, Csaba E. Móré, András Vargha et al. 88 citations

Studying the effect of psychedelic substances on expression of creativity is a challenging problem. Our primary objective was to study the psychometric measures of creativity after a series of ayahuasca ceremonies at a time when the acute effects have subsided. The secondary objective was to investigate how entoptic phenomena emerge during expression of creativity. Forty individuals who were...

DOI: 10.1080/02791072.2012.703099 (opens in new tab) Ayahuasca Creativity Expression computer science Ceremony +2

A Study of Ayahuasca Use in North America

Journal of Psychoactive Drugs July 1, 2012 Rachel Harris, Lee Gurel 69 citations

Eighty-one subjects who used ayahuasca at least once in North America answered a lengthy set of open-ended questions and completed the 81-item After the Spiritual Experience Questionnaire. An additional 50 ayahuasca users were interviewed in person. The data for this study represent ayahuasca experience based on more than 2,267 ceremonies. A comparison group of 46 people attending a Catholic...

Hypotheses Regarding the Mechanisms of Ayahuasca in the Treatment of Addictions

Journal of Psychoactive Drugs July 1, 2012 Mitchell B. Liester, James I. Prickett 78 citations

Ayahuasca is a medicinal plant mixture utilized by indigenous peoples throughout the Amazon River basin for healing purposes. The "vine of the soul" or "vine of death," as it is known in South America, contains a combination of monoamine oxidase inhibitors and N,N-dimethyltryptamine (DMT). When ingested together, these medicines produce profound alterations in consciousness. Increasingly,...

Avaliação dos efeitos neurotóxicos do chá ayahuasca

June 12, 2012 Alex Roberto Melgar Figueroa

\n O chá ayahuasca é uma bebida psicotrópica que tem provocado polêmica devido ao uso indiscriminado por alguns grupos de pessoas e pela facilidade de compra pela internet. A bebida é feita por meio da decocção conjunta das plantas Banisteriopsis Caapi e Psychotria Viridis. Contém alcaloides beta-carbolínicos (?-carbolínicos) como harmina (HRM), harmalina (HRL) e harmalol, que possuem efeitos...

Developments in harmine pharmacology — Implications for ayahuasca use and drug-dependence treatment

Progress in Neuro-Psychopharmacology and Biological Psychiatry June 10, 2012 Daniel I. Brierley, Colin Davidson 133 citations

Ayahuasca is a hallucinogenic botanical mixture originating in the Amazon area where it is used ritually, but is now being taken globally. The 2 main constituents of ayahuasca are N,N-dimethyltryptamine (DMT), a hallucinogen, and harmine, a monoamine oxidase inhibitor (MAOI) which attenuates the breakdown of DMT, which would otherwise be broken down very quickly after oral consumption. Recent...

Ayahuasca characterization, metabolism in humans, and relevance to endogenous N,N-dimethyltryptamines

June 8, 2012 Ethan H. Mcilhenny 1 citation

Ayahuasca denotes an Amazonian psychotropic plant tea obtained from Banisteriopsis caapi, which contains beta-carboline (b-carboline) alkaloids, chiefly harmine, harmaline and tetrahydroharmine. The tea usually incorporates the leaves of Psychotria viridis, which are rich in N,N-dimethyltryptamine (DMT), a psychoactive 5-HT2A agonist. The beta-carbolines reversibly inhibit monoamine-oxidase...

Metabolism and disposition of N,N‐dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca

Drug Testing and Analysis April 19, 2012 Jordi Riba, Ethan H. Mcilhenny, Marta Valle et al. 91 citations

Ayahuasca is an Amazonian psychotropic plant tea obtained from Banisteriopsis caapi , which contains β ‐carboline alkaloids, chiefly harmine, harmaline and tetrahydroharmine. The tea usually incorporates the leaves of Psychotria viridis or Diplopterys cabrerana , which are rich in N , N ‐dimethyltryptamine (DMT), a psychedelic 5‐HT 2A/1A/2C agonist. The β ‐carbolines reversibly inhibit...

DOI: 10.1002/dta.1344 (opens in new tab) Ayahuasca Harmine Harmaline Alkaloid +8

(Neo)Shamanic Dialogues

Nova Religio: The Journal of Alternative and Emergent Religions April 13, 2012 Esther Jean Langdon, Isabel Santana de Rose 17 citations

This paper is a reflection on the ritual incorporation of ayahuasca, an Amazonian psychoactive ritual substance, by members of a Guarani Indian village on the Atlantic coast of the state of Santa Catarina, Brazil. Their shamanic leaders have adapted the use of this beverage into their ritual practices and recognize it as part of their culture and tradition. This process of appropriation is a...

Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks

Microchemical Journal April 5, 2012 Alain Gaujac, Sabrina Teixeira Martinez, Arão Araújo Gomes et al. 34 citations

N,N-dimethyltryptamine (DMT) is a psychoactive indole alkaloid present in beverages consumed in religious ceremonies and in neo-shamanic rituals all around the world. It is a substance banned in most countries, which makes its acquisition difficult. In Brazil, a beverage rich in DMT named ayahuasca is legally consumed in a religious context. On the other hand, DMT is a controlled drug, enforced...

DOI: 10.1016/j.microc.2012.03.033 (opens in new tab) Ayahuasca Context archaeology Mass spectrometry Designer drug +2

Personal Report: Significance of Community in an Ayahuasca Jungle Dieta

Anthropology of Consciousness March 1, 2012 Bethe Hagens, Steven Lansky 4 citations

Abstract What is the potential significance of community in a prolonged dieta (10‐day restricted diet with regular ritual consumption of ayahuasca and other medicinal plants) in a remote jungle location in the A mazon basin of P eru? Pre‐dieta experiences including how participants join the community, cleansing routines prior to departure to P eru, sharing with the shaman one's personal...

The Creative Cycle Processes Model of Spontaneous Imagery Narratives Applied to the Ayahuasca Shamanic Journey

Anthropology of Consciousness March 1, 2012 Frank Echenhofer 8 citations

Abstract Ayahuasca is an A mazonian psychoactive shamanic brew that often elicits spontaneous, intense, and meaningful imagery narratives related to psychological and physical healing, problem solving, knowledge acquisition, community cohesion, creativity, and spiritual development. My EEG and phenomenology ayahuasca research found it caused the greatest changes in EEG beta coherence from 25 to...

DOI: 10.1111/j.1556-3537.2012.01057.x (opens in new tab) Ayahuasca Narrative Experiential learning Phenomenology philosophy +8

Ayahuasca Religions in Acre: Cultural Heritage in the Brazilian Borderlands

Anthropology of Consciousness March 1, 2012 Beatriz Caiuby Labate 21 citations

Abstract The B razilian ayahuasca religions, S anto D aime, B arquinha, and U nião do V egetal, have increasingly sought formal recognition by government agencies in B razil and other countries to guarantee their legal use of ayahuasca, which contains DMT , a substance that is listed. This article focuses on new alliances and rifts that have emerged between and among different ayahuasca groups...

DOI: 10.1111/j.1556-3537.2012.01058.x (opens in new tab) Ayahuasca Legitimacy Amazon rainforest Politics +9

Working with “La Medicina”: Elements of Healing in Contemporary Ayahuasca Rituals

Anthropology of Consciousness March 1, 2012 Evgenia Fotiou 44 citations

Abstract Healing is an essential aspect of A mazonian mestizo shamanism. Not only is it one of the most commonly quoted motives for W esterners for participating in ayahuasca ceremonies, but most elements of an ayahuasca ceremony are aimed to heal and protect. This article is purely ethnographic, and its purpose is to provide insight into the ways healing is conceived by both ayahuasqueros and...

Ayahuasca as Antidepressant? Psychedelics and Styles of Reasoning in Psychiatry

Anthropology of Consciousness March 1, 2012 B. Anderson 29 citations

Abstract There is a growing interest among scientists and the lay public alike in using the S outh A merican psychedelic brew, ayahuasca, to treat psychiatric disorders like depression and anxiety. Such a practice is controversial due to a style of reasoning within conventional psychiatry that sees psychedelic‐induced modified states of consciousness as pathological. This article analyzes the...

Healing with Plant Intelligence: A Report from Ayahuasca

Anthropology of Consciousness March 1, 2012 Richard Doyle 26 citations

Abstract Numerous and diverse reports indicate the efficacy of shamanic plant adjuncts (e.g., iboga, ayahuasca, psilocybin) for the care and treatment of addiction, post‐traumatic stress disorder, cancer, cluster headaches, and depression. This article reports on a first‐person healing of lifelong asthma and atopic dermatitis in the shamanic context of the contemporary P eruvian A mazon and the...