Cameron M. Longo

2 papers in the library · 39 citations · publishing 2019-2020

Papers

An Efficient Ambient Ionization Mass Spectrometric Approach to Detection and Quantification of the Mescaline Content of Commonly Abused Cacti from the Echinopsis Genus

Journal of Forensic Sciences July 16, 2019 Cameron M. Longo, Rabi A. Musah 22 citations

A rapid screening and quantification method using DART-HRMS detects mescaline in cactus tissue. The method is validated with calibration curves showing R² values of at least 0.995, a lower limit of quantification of 1 ppm, and a linear range of 1–100 ppm. Applied to commercially available Echinopsis species, mescaline levels were less than 2% dry weight in all samples, consistent with previous GC- and LC-MS studies. DART-HRMS is suitable for quickly identifying mescaline and measuring its concentration in complex plant materials.

DOI: 10.1111/1556-4029.14134 Mescaline Dart ion source Cactus Gas chromatography–mass spectrometry +1

Detection and Quantification of Psychoactive N,N-Dimethyltryptamine in Ayahuasca Brews by Ambient Ionization High-Resolution Mass Spectrometry

ACS Omega October 27, 2020 Megan I. Chambers, Meghan G. Appley, Cameron M. Longo et al. 17 citations

A rapid method using direct analysis in real time-high-resolution mass spectrometry (DART-HRMS) quantifies N,N-dimethyltryptamine (DMT) in ayahuasca brews without lengthy sample preparation. The technique also identifies the beverage by detecting secondary metabolites from its plant ingredients. Analysis of six ayahuasca brews made with different combinations of DMT- and harmala alkaloid-containing plants found DMT levels ranging from 45.7 to 230.5 mg/L, consistent with values from conventional methods.

DOI: 10.1021/acsomega.0c03196 Ayahuasca Dart ion source Chemistry Mass spectrometry