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Stefan G Hofmann

27 papers in the library · 1,188 citations · publishing 2010-2026

Papers

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Efficacy and mechanisms of internet-delivered mindfulness-based cognitive therapy for Adjustment Disorder: A randomized controlled trial.

Journal of Anxiety Disorders July 1, 2026 Paweł Holas, Jan Wardęszkiewicz, Malgorzata Grochowska et al.

Adjustment Disorder (AjD) is a common stress-related condition, yet evidence-based interventions remain scarce. Mindfulness-Based Cognitive Therapy (MBCT) targets transdiagnostic mechanisms such as cognitive fusion and low self-compassion, which may be particularly relevant for AjD. This randomized controlled trial tested the efficacy of a brief, guided, asynchronous internet-delivered MBCT...

Temporal Precedence of Distress Tolerance in Predicting Anxiety and Depression: A Daily Diary Approach During Mindfulness-Based Intervention.

Behavior therapy May 1, 2026 Yanjuan Li, Amy Hu, Yiran Ding et al.

This study used a daily diary method to examine the temporal relationship between distress tolerance (DT), anxiety, and depression during a mindfulness-based intervention (MBI). A total of 83 participants with high emotional distress completed daily diaries of mindfulness, DT, anxiety and depression over one week before, during, and after the intervention. Linear mixed models showed significant...

Acting with Acceptance, Mindfulness and Compassion to Cope with Test and Exam Anxiety (AcAdeMiC): Preliminary Efficacy From a Pilot Randomized Trial

Mindfulness May 1, 2026 Cláudia P. Pires, Julieta Azevedo, Raquel Guiomar et al.

Abstract Objectives Research on structured, manualized psychotherapeutic interventions for high test anxiety (TA) in adolescents remains limited, particularly those integrating acceptance, mindfulness, and compassion-based strategies. These psychological processes have been identified as protective factors for test anxiety, fostering adaptive emotional regulation and resilience. The AcAdeMiC...

Effect of cognitive flexibility in mindfulness intervention for emotional distress: Two randomized controlled trials.

Journal of Counseling Psychology July 14, 2025 Zhenzhen Wang, Mo Chen, Amy Hu et al. 2 citations

To examine the mechanistic role of cognitive flexibility in mindfulness intervention for emotional distress (MIED), we conducted two randomized controlled trials. In Study 1, 607 participants experiencing high emotional distress were randomly assigned to either an MIED program group (N = 304) or a waitlist control group (N = 303). Levels of cognitive flexibility, anxiety, depression, and...

Influence of anxiety sensitivity on the observe facet of the five facet mindfulness questionnaire: differential item functioning in a clinical population.

BMC Psychiatry April 1, 2025 Danielle Moskow Diamond, Joshua Curtiss, Joseph K. Carpenter et al. 4 citations

Many individuals who engage in mindfulness experience decreased anxiety. Yet some individuals, particularly those with panic disorder (PD) or elevated anxiety sensitivity (AS), note heightened anxiety when observing particular sensations. The Five Facet Mindfulness Questionnaire (FFMQ) is one of the most widely utilized mindfulness questionnaires. However, its Observe facet has shown...

Supported Mindfulness-Based Self-Help Intervention as an Adjunctive Treatment for Rapid Symptom Change in Emotional Disorders: A Practice-Oriented Multicenter Randomized Controlled Trial.

Psychotherapy and Psychosomatics 2025 Yanjuan Li, Yi Zhang, Chun Wang et al. 13 citations

Rapid symptom relief is crucial for individuals with emotional disorders. The current study aimed to determine whether facilitator-supported mindfulness-based self-help (MBSH) intervention as an adjunctive treatment could provide rapid improvement for individuals with emotional disorders. A practice-oriented randomized controlled trial was conducted on a sample of 302 patients with emotional...

Decentering as a mediator of the effect of mindfulness on emotional distress: Evidence from cross-sectional and longitudinal designs.

Psychotherapy research : journal of the Society for Psychotherapy Research November 17, 2024 Zhenzhen Wang, Xinyi Tang, Amy Hu et al. 5 citations

To investigate the role of decentering as a mediator of the effect of mindfulness/mindfulness-based intervention (MBI) on emotional distress, we conducted cross-sectional and longitudinal designs. In Study 1, a total of 998 participants with high emotional distress were included. Mindfulness, decentering, anxiety, and depression were measured at baseline. In Study 2, 688 participants with high...

Mindfulness as a therapeutic option for obsessive-compulsive disorder.

Expert Review of Neurotherapeutics August 1, 2024 Andreas Reis, Marlon Westhoff, Hicham Quintarelli et al.

Obsessive-compulsive disorder (OCD) is a prevalent mental health issue characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions) that can cause significant life impairment. Despite cognitive-behavioral therapy (CBT) being the most effective treatment, some individuals experience insufficient symptom reduction or relapse. This special report explores the potential...

Changes in mindfulness facets across yoga, CBT and stress education in individuals with generalized anxiety disorder.

Journal of Mood and Anxiety Disorders June 1, 2024 Danielle Moskow Diamond, David Rosenfield, Nikki Kaiser et al. 5 citations

Improving mindfulness is an important treatment target for generalized anxiety disorder (GAD). However, less is known about how different treatments impact specific aspects of mindfulness. In a clinical trial (Simon et al., 2021), 226 individuals with GAD were randomized to 12 weeks of Kundalini Yoga (KY), cognitive behavioral therapy (CBT) or stress education (SE). To examine whether specific...

[Video-Based Online Metta-Meditation Therapy for Depression: A Pilot Trial Evaluating the Acceptability and Feasibility].

Verhaltenstherapie April 1, 2024 Elisabeth A. Arens, Lucas Donnerstag, Stefan G Hofmann et al. 1 citation

In the course of the Covid-19 pandemic, it has become clear what relevance non-contact psychotherapeutic online interventions in mental health care could possibly have in the future. The present pilot study aims to test whether a Metta-based group program is also an acceptable and feasible treatment when conducted as video-based intervention. Metta meditations aim at showing unconditional...

Distress tolerance as a mediator of mindfulness-based intervention for anxiety and depression: Evidence from two randomized controlled trials.

International journal of clinical and health psychology : IJCHP 2024 Yanjuan Li, Mengyao He, Zhenzhen Wang et al. 18 citations

We aimed to investigate whether distress tolerance mediated the effects of mindfulness-based intervention (MBI) on anxiety and depression with two randomized controlled studies. In Study 1, 374 participants with at least moderate emotional distress were randomized to an intervention group (N = 174) and a waitlist control group (N = 173). Mindfulness, distress tolerance, anxiety, and depression...

Hype or hope? High placebo response in major depression treatment with ketamine and esketamine: a systematic review and meta-analysis.

Frontiers in Psychiatry 2024 Alexandros Matsingos, Marcel Wilhelm, Laila Noor et al. 18 citations

Ketamine and esketamine offer a novel approach in the pharmacological treatment of major depressive disorder (MDD). This meta-analysis aimed to investigate the placebo response in double-blind, randomized controlled studies (RCTs) on patients with MDD receiving ketamine or esketamine. For this systematic review and meta-analysis Medline (PubMed), Cochrane Central Register of Controlled Trials...

The Role of Attentional Control in Mindfulness Intervention for Emotional Distress: A Randomized Controlled Trial With Longitudinal Mediation Analyses.

Clinical Psychology & Psychotherapy 2024 Zhenzhen Wang, Kaerqika Shalihaer, Stefan G Hofmann et al. 10 citations

This study aimed to investigate whether attentional control serves as a mediator for mindfulness-based interventions for emotional distress, utilizing a randomized waitlist (WL)-controlled design. A total of 498 participants with high emotional distress was recruited online and randomly assigned to a 49-day online Mindfulness Intervention for Emotional Distress (MIED) group (N = 249) or a WL...

Distress tolerance as a mechanism of mindfulness for depression and anxiety: Cross-sectional and diary evidence

International Journal of Clinical and Health Psychology July 5, 2023 Yanjuan Li, Ruilin Ju, Stefan G Hofmann et al.

Background Both trait and state mindfulness are associated with less depression and anxiety, but the mechanisms remain unknown. Distress tolerance, an important transdiagnostic factor of emotional disorders, may mediate the relationship between mindfulness and depression/anxiety. Method Study 1 examined the mediation model at the between-person level in a large cross-sectional sample (n = 905)....

Metta-Based Therapy for Chronic Depression: a Wait List Control Trial

Mindfulness October 8, 2021 Ulrich Stangier, Artjom Frick, Isabel Thinnes et al. 11 citations

Objectives: Current treatments for chronic depression have focused on reducing interpersonal problems and negative affect, but paid little attention to promoting prosocial motivation and positive affect. Following this treatment focus, the objective of the present study was to examine whether the combination of metta (Loving Kindness) group meditation and subsequent tailored individual therapy...

Loving-Kindness Meditation Promotes Mental Health in University Students

Mindfulness May 2, 2020 Christina Totzeck, Tobias Teismann, Stefan G Hofmann et al. 62 citations

Abstract Objectives Loving-kindness meditation (LKM) has been shown to improve wellbeing and positive emotions in clinical and non-clinical populations. The main goal of the present study was to examine whether LKM might be an effective intervention to promote positive mental health using the Positive Mental Health Scale (PMH) and to decrease depression, anxiety, and stress in university...

The Relationship Between Trait Mindfulness and Affective Symptoms: A Meta-analysis of the Five Facet Mindfulness Questionnaire (FFMQ)

Clinical Psychology Review November 11, 2019 Joseph K. Carpenter, Kristina Conroy, Angelina F Gómez et al.

Trait mindfulness appears to be related to lower levels of negative affective symptoms, but it remains uncertain which facets of mindfulness are most important in this relationship. Accordingly, the present meta-analysis examined studies reporting correlations between affective symptoms and trait mindfulness as assessed by the Five Facet Mindfulness Questionnaire. A comprehensive search yielded...

Integrating Metta Into CBT: How Loving Kindness and Compassion Meditation Can Enhance CBT for Treating Anxiety and Depression

Clinical Psychology in Europe September 18, 2019 Simona Stefan, Stefan G Hofmann 24 citations

Loving kindness meditation and compassion meditation are traditional Buddhist practices that have recently been introduced and investigated in psychotherapy with promising results. Both meditation practices emphasize metta, a mental state of positive energy and kindness towards oneself and other beings, as opposed to the anger, hostility, or self-loathing that often accompany emotional...

Loving Kindness Meditation zur Behandlung der chronischen Depression

Zeitschrift für Klinische Psychologie und Psychotherapie July 1, 2018 Viola N. L. S. Schilling, W. Lutz, Stefan G Hofmann et al.

Zusammenfassung. Theoretischer Hintergrund: Chronische Depressionen gehen mit einer langwierigen Belastung einher und verursachen hohe Krankheitskosten. Ein möglicher Ansatz zur Behandlung könnte die Loving Kindness Meditation (LKM) sein. Methode: In dieser Pilot-Studie wurde ein LKM-Gruppenprogramm eingesetzt und bezüglich der Effektivität untersucht. N = 2207 Fälle aus Wartelistendaten wurden...

Know Thyself: Well-Being and Subjective Experience

Cerebrum 2018 Joseph E LeDoux, Richard Brown, D. Pine et al.

Editor’s Note The study of subjective experience represents a significant challenge to cognitive scientists, but one that is beginning to be increasingly addressed. Subjectivity renders experience less amenable to traditional objective scientific measurements than other subject matter. Our authors believe that when seeking to understand the mind, subjectivity must ultimately be investigated and...

Mindfulness-Based Interventions for Anxiety and Depression

Psychiatric Clinics of North America September 18, 2017 Stefan G Hofmann, Angelina F Gómez

Synopsis This article reviews the ways in which cognitive and behavioral treatments for depression and anxiety have been advanced by the application of mindfulness practices. Research on mindfulness-based interventions (MBIs) has increased exponentially in the past decade. The most common include Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT). MBIs have...

Loving-Kindness Meditation to Target Affect in Mood Disorders: A Proof-of-Concept Study

Evidence-based Complementary and Alternative Medicine 2015 Stefan G Hofmann, Nicola Petrocchi, James Steinberg et al. 70 citations

Conventional treatments for mood disorders primarily focus on reducing negative affect, but little on enhancing positive affect. Loving-kindness meditation (LKM) is a traditional meditation practice directly oriented toward enhancing unconditional and positive emotional states of kindness towards oneself and others. We report here two independent and uncontrolled studies carried out at...

Loving-kindness and compassion meditation: potential for psychological interventions.

Clin Psychol Rev July 26, 2011 Stefan G Hofmann, Paul Grossman, Devon E Hinton 945 citations

Mindfulness-based meditation interventions have become increasingly popular in contemporary psychology. Other closely related meditation practices include loving-kindness meditation (LKM) and compassion meditation (CM), exercises oriented toward enhancing unconditional, positive emotional states of kindness and compassion. This article provides a review of the background, the techniques, and...

The Effect of Mindfulness-Based Therapy on Anxiety and Depression: A Meta-Analytic Review

Journal of Consulting and Clinical Psychology April 1, 2010 Stefan G Hofmann, Alice T. Sawyer, Ashley A. Witt et al.

BACKGROUND Although mindfulness-based therapy has become a popular treatment, little is known about its efficacy. OBJECTIVES To conduct an effect size analysis of this popular intervention for anxiety and mood symptoms in clinical samples. DATA SOURCES A literature search was conducted using PubMed, PsycInfo, the Cochrane Library, and manual searches. REVIEW METHODS The search identified 39...

The influence of anxiety sensitivity on mindfulness

Danielle M Moskow, Joshua Curtiss, Joseph K. Carpenter et al. preprint

Although many individuals who engage in mindfulness endorse less anxiety, others experience heightened anxiety when focusing on particular sensations. This study aimed to determine whether specific mindfulness items related to observing internally or externally differ in individuals with panic disorder (PD) or elevated anxiety sensitivity (AS). We examined a clinical sample of 1521 Japanese...