Psychotherapy and Psychosomatics
June 19, 2026
Judith Rohde, Tyler M Moore, Kathryn Walker et al.
Ketamine combined with psychotherapy has shown promise in treating posttraumatic stress disorder (PTSD), but predictors of clinical benefit remain unclear. In this systematic review and individual participant data meta-analysis (IPDMA), we examined patient- and treatment-level predictors of PTSD symptom change after combined treatment. Eligible studies combined ketamine with psychotherapy in...
Psychotherapy and Psychosomatics
June 12, 2026
Thorsten Barnhofer, Maria Niemi, Johannes Michalak et al.
1 citation
INTRODUCTION: Around a third of patients with major depressive disorder experience persistent symptoms despite usual treatments. Identifying scalable, psychological treatment options is critical to reduce the burden associated with difficult-to-treat depression (DTD). We examined the efficacy of mindfulness-based cognitive therapy (MBCT) compared with treatment as usual (TAU) and other active...
Psychotherapy and Psychosomatics
May 27, 2026
Lea J. Mertens, Felix Betzler, Manuela Brand et al.
Psilocybin shows promise for treatment-resistant depression (TRD), but long-term data are limited. This study examined the antidepressant effect of one or two psilocybin doses with adjunct psychotherapy in TRD until twelve months. This is a naturalistic follow-up of a phase 2b, randomized, active placebo-controlled trial, where participants were randomized to receive two drug administrations...
Psychotherapy and Psychosomatics
March 30, 2026
Sophie Grigoriadis, Neeti Sharma, Cindy-Lee Dennis et al.
Anxiety during pregnancy affects 1 in 4 pregnancies and is often comorbid with other mental health disorders. Early intervention is crucial to avoid persistent mental health issues and adverse obstetrical, neonatal and child outcomes. Traditional mindfulness-based cognitive therapy is effective, but its uptake is limited by its high resource intensity for patients and healthcare services. This...
Psychotherapy and Psychosomatics
2026
Maria Serra-Blasco, Neus Miquel-Giner, Muriel Vicent-Gil et al.
Introduction: Obsessive-compulsive disorder (OCD) is a chronic condition where many patients remain symptomatic despite first-line treatments such as cognitive behavioural therapy and selective serotonin reuptake inhibitors. This randomised controlled trial evaluated mindfulness-based cognitive therapy (MBCT) efficacy as an augmentation strategy and its impact on brain functional connectivity....
Psychotherapy and Psychosomatics
2025
Yanjuan Li, Yi Zhang, Chun Wang et al.
13 citations
Rapid symptom relief is crucial for individuals with emotional disorders. The current study aimed to determine whether facilitator-supported mindfulness-based self-help (MBSH) intervention as an adjunctive treatment could provide rapid improvement for individuals with emotional disorders. A practice-oriented randomized controlled trial was conducted on a sample of 302 patients with emotional...
Psychotherapy and Psychosomatics
2025
Jojo Yan Yan Kwok, Lily Man Lee Chan, Charis Ann Lai et al.
13 citations
Clinical guidelines recommend a holistic approach to Parkinson's disease (PD) care, yet randomized trials examining mindfulness-based interventions in this context are scarce. This study investigated the effects of two mindfulness practices - meditation and yoga - on biopsychosocial outcomes in PD patients, including anxiety symptoms, depressive symptoms, motor/nonmotor symptoms, health-related...
Psychotherapy and Psychosomatics
2025
Louise Sharpe, Madelyne A Bisby, Rachel E. Menzies et al.
7 citations
This study aimed to determine the relative efficacy of mindfulness-based stress reduction (MBSR) or cognitive behaviour therapy (CBT) in comparison to a waitlist control (WLC) for people with rheumatoid arthritis (RA). Participants completed assessments before and after treatment and at 6-month follow-up. Two hundred and sixty-nine participants with RA were recruited and randomised in a 2:2:1...
Psychotherapy and Psychosomatics
2021
Samuel t. Wilkinson, Taeho greg Rhee, Jutta Joormann et al.
102 citations
<b><i>Introduction:</i></b> Ketamine has emerged as a rapid-acting antidepressant. While ongoing treatment can prevent relapse, concerns exist regarding long-term exposure. <b><i>Objective:</i></b> We conducted a randomized trial to examine the feasibility and efficacy of cognitive behavioral therapy (CBT) following intravenous ketamine in treatment-resistant depression (TRD)....
Psychotherapy and Psychosomatics
2021
Carolin Schmid, Kathrin Hansen, Tana Kröner-Borowik et al.
Both imagery rescripting and imaginal exposure have been proven to be effective in the treatment of chronic nightmares when compared to a waitlist condition. Little is known about their comparative efficacy and their efficacy compared to an active control. The aims of this study were to compare the two treatments to one another and to positive imagery as an active control, and to explore...
Psychotherapy and Psychosomatics
2020
Fabrizio Schifano
19 citations
© 2020 S. Karger AG, Basel. This is the peer-reviewed but unedited manuscript version of the following article: Schifano F: Coming Off Prescribed Psychotropic Medications: Insights from Their Use as Recreational Drugs. Psychother Psychosom 2020;89:274-282. DOI: 10.1159/000361001. The final, published version is available at https://doi.org/10.1159/000507897.
Psychotherapy and Psychosomatics
2017
Samuel T. Wilkinson, Dashaun Wright, Madonna K. Fasula et al.
120 citations
<b><i>Introduction:</i></b> Ketamine has shown rapid though short-lived antidepressant effects. The possibility of concerning neurobiological changes following repeated exposure to the drug motivates the development of strategies that obviate or minimize the need for longer-term treatment with ketamine. In this open-label trial, we investigated whether cognitive behavioral therapy (CBT) can...
Psychotherapy and Psychosomatics
2017
Annika Gieselmann, Max Böckermann, Marjolijn Sorbi et al.
Nightmares are extremely dysphoric dreams, which are prevalent and associated with psychological strain. This study investigated (a) the efficacy of an internet-based imagery rehearsal therapy (IRT), (b) the role of imagery rescription, and (c) the role of guidance during internet-based IRT. A total of 127 patients suffering from mainly idiopathic nightmares were randomly assigned to 1 of 2 IRT...
Psychotherapy and Psychosomatics
2016
Stuart J. Eisendrath, Erin P Gillung, Kevin L. Delucchi et al.
193 citations
BACKGROUND: Due to the clinical challenges of treatment-resistant depression (TRD), we evaluated the efficacy of mindfulness-based cognitive therapy (MBCT) relative to a structurally equivalent active comparison condition as adjuncts to treatment-as-usual (TAU) pharmacotherapy in TRD. METHODS: This single-site, randomized controlled trial compared 8-week courses of MBCT and the Health...
Psychotherapy and Psychosomatics
2013
Eric L Garland, Matthew O. Howard
Background: Chronic pain involves hypervigilance for pain-related stimuli. Selective attention to pain-related stimuli, known as pain attentional bias (AB), can exacerbate chronic pain, prolong suffering, and undermine quality of life. The aim of this study was to determine if a multimodal mindfulness-oriented intervention could significantly reduce pain AB among chronic pain patients receiving...
Psychotherapy and Psychosomatics
February 18, 2010
John A. Astin
628 citations
BACKGROUND: This study examined the effects of an 8-week stress reduction program based on training in mindfulness meditation. Previous research efforts suggesting this program may be beneficial in terms of reducing stress-related symptomatology and helping patients cope with chronic pain have been limited by a lack of adequate comparison control group. METHODS: Twenty-eight individuals who...
Psychotherapy and Psychosomatics
February 18, 2010
Antonio Zadra, Robert O. Pihl
120 citations
BACKGROUND: Lucid dreams occur when a person becomes aware that he or she is dreaming while still in the dream state. Previous reports on the use of lucid dreaming in the treatment of nightmares do not contain adequate baseline data, follow-up data, or both. METHODS: A treatment of recurrent nightmares incorporating progressive muscle relaxation, guided imagery, and lucid dream induction is...
Psychotherapy and Psychosomatics
February 18, 2010
Douglas E. Webb, Joen Fagan
10 citations
Subjects reporting a recurring dream at least 4 times a month for a year or more were assigned to a dream recording control group and an experimental group which used muscle testing to guide dream interpretation. Dream frequency was recorded prior to and following a dream interpretation intervention (experimental subjects) or dream reporting session (control subjects). Dream frequency declined...
Psychotherapy and Psychosomatics
February 18, 2010
Gail Q. Heather-Greener, Dana Comstock, Roby Joyce
Background: Clinical observations of a relationship between unpleasant dreams and migraine headaches have been reported previously. Methods: Due to the anecdotal quality of these case reports, this study empirically investigated the significance of this relationship. Dream content categories were selected corresponding to emotional factors associated with stress that trigger migraine headaches....
Psychotherapy and Psychosomatics
February 17, 2010
Chang-Yong Chung
9 citations
The author emphasizes the therapist's well-integrated and matured personality as the crucial element for being a good psychotherapist; therefore, it is essential for a psychotherapist to make ceaseless efforts regarding his own personality growth with his ongoing therapeutic experiences. Nevertheless, nowadays students are apt to satisfy themselves with or cling to the theories and techniques...
Psychotherapy and Psychosomatics
February 16, 2010
Yujiro Ikemi, Hitoshi Ishikawa, J.R.M. Goyeche et al.
As practices of altered states of consciousness (ASC) have become more widely used among psychotherapists who have become aware of the limitations of psychoanalytic, educational and behavioral approaches, negative aspects (‘Makyo’) of ASC have drawn their special attention. For the purpose of controlling or preventing these side-effects, (1) the problem of indication is most important, (2) and...
Psychotherapy and Psychosomatics
February 12, 2010
Hector Warnes
6 citations
The functions and dysfunctions of slow wave sleep and of REM sleep and its associated dreams have a tremendous significance in understanding the psychosomatic model of illness and in establishing preventive strategies. Ten patients suffering from a variety of psychosomatic illnessess spent 3-4 nights sleeping at the Dream Laboratory. A psychiatric evaluation was carried out and those suffering...
Psychotherapy and Psychosomatics
2010
Jaap Lancee, Victor I. Spoormaker, Jan Van den Bout
Several cognitive-behavioral techniques are effective in reducing nightmare frequency, but the therapeutic factor (e.g. cognitive restructuring, systematic desensitization) remains unclear. The aim of this study was to compare the nightmare treatments imagery rehearsal therapy (IRT), exposure, and recording (keeping a diary)--in a self-help format--with a waiting list. Participants were...
Psychotherapy and Psychosomatics
2007
Lutz Wittmann, Michael Schredl, Milton Kramer
This review summarizes the available knowledge on the phenomenology of posttraumatic dreams. Posttraumatic nightmares are reported by up to 70% of individuals suffering from posttraumatic stress disorder (PTSD). An extensive review of polysomnographic studies suggests that neither this high incidence nor the occurrence of posttraumatic nightmares throughout the sleep cycle can be explained by...
Psychotherapy and Psychosomatics
2007
Ludwig Grepmair, Ferdinand Mitterlehner, Thomas Loew et al.
All therapists direct their attention in some manner during psychotherapy. A special form of directing attention, 'mindfulness', is recommended. This study aimed to examine whether, and to what extent, promoting mindfulness in psychotherapists in training (PiT) influences the treatment results of their patients. The therapeutic course and treatment results of 124 inpatients, who were treated...