PNAS Nexus
July 1, 2026
David S Jin, Oumayma Agdali, Taruna Yadav et al.
Awareness of action (AoA), or conscious awareness of an action just performed, is an important part of daily experience with major practical and ethical relevance, yet the neural mechanisms of AoA remain largely unknown. The main barrier to studying AoA is a lack of experimental paradigms to directly compare neural activity in aware versus unaware actions. Borrowing from the field of perceptual...
PNAS Nexus
March 1, 2026
Lina Jeantin, Pierre Bourdillon, Marc Guenot et al.
Electroencephalography (EEG) signal complexity reflects the richness of brain activity and is considered a marker of consciousness. However, its normative values across physiological conscious states using intracranial EEG (iEEG) across cortical areas remain poorly defined. We aimed at referencing iEEG complexity in the human brain and its links with global states of consciousness. We analyzed...
PNAS Nexus
September 1, 2025
Xin Luo, Huabin Wang, Xuefeng Xu et al.
Internet gaming disorder (IGD) frequently co-occurs with depression. IGD and depression have overlapping and distinct biological and psychological substrates. Mindfulness meditation (MM) has demonstrated efficacy in treating IGD and depression separately. However, its efficacy in treating concurrent IGD and depression and the possible brain mechanisms remain largely unknown. Seventy individuals...
PNAS Nexus
April 1, 2025
Katie Zhou, David de Wied, Robin Carhart-Harris et al.
9 citations
Interest in using psychedelic drugs to treat psychiatric disorders is growing rapidly. While modern controlled clinical trials show a favorable safety and efficacy profile, it remains unclear if the risk of side effects would increase with broader use in more heterogeneous populations. To address this, we investigated the frequency and baseline predictors of delusional ideation, magical...
PNAS Nexus
December 1, 2024
Emilia Fló, Laouen Belloli, Álvaro Cabana et al.
10 citations
Attention shapes our consciousness content and perception by increasing the probability of becoming aware and/or better encoding a selection of the incoming inner or outer sensory world. Engaging interoceptive and exteroceptive attention should elicit distinctive neural responses to visceral and external stimuli and could be useful in detecting covert command-following in unresponsive patients....
PNAS Nexus
February 29, 2024
Félix Schoeller, Leonardo Christov-Moore, Caitlin Lynch et al.
Abstract Why does the same experience elicit strong emotional responses in some individuals while leaving others largely indifferent? Is the variance influenced by who people are (personality traits), how they feel (emotional state), where they come from (demographics), or a unique combination of these? In this 2,900+ participants study, we disentangle the factors that underlie individual...
PNAS Nexus
February 1, 2024
Benjy Barnett, Lau M Andersen, Stephen M Fleming et al.
7 citations
Some conscious experiences are more vivid than others. Although perceptual vividness is a key component of human consciousness, how variation in this magnitude property is registered by the human brain is unknown. A striking feature of neural codes for magnitude in other psychological domains, such as number or reward, is that the magnitude property is represented independently of its sensory...
PNAS Nexus
December 19, 2023
Guglielmo Foffani
17 citations
To be or not to be hallucinating: Implications of hypnagogic/hypnopompic experiences and lucid dreaming for brain disorders.