Philosophical Perspectives on Psychedelic Psychiatry
September 13, 2024
David B. Yaden, Sandeep M. Nayak, Roland R. Griffiths
4 citations
Abstract The proportion of people who change their metaphysical beliefs after psychedelic experiences is not yet known with specificity. However, it appears that belief changes can occur in some cases, and evidence more precisely estimating the prevalence and magnitude of such belief changes is accruing. The evidence for metaphysical belief changes is reviewed and the potential psychological...
Medicine, Health Care, and Philosophy
September 1, 2024
Judith N Wagner
Chronic pain is a common disorder with enormous sociomedical importance. A major part of primary and secondary costs of illness is caused by the various pain syndromes. Nociception - the sensory perception of a painful stimulus - is a complex process relying on an intricate system of anatomical, neurophysiological and biochemical networks. This applies even more so to pain - the state of...
Consciousness and Cognition
September 1, 2024
Asger Kirkeby-Hinrup, Jakob Stenseke, Morten Overgaard
The recent "Conscious Turing Machine" (CTM) proposal offered by Manuel and Lenore Blum aims to define and explore consciousness, contribute to the solution of the hard problem, and demonstrate the value of theoretical computer science with respect to the study of consciousness. Surprisingly, given the ambitiousness and novelty of the proposal (and the prominence of its creators), CTM has...
European Archives of Psychiatry and Clinical Neuroscience
September 1, 2024
Helene Stephensen, Annick Urfer-Parnas, Josef Parnas
28 citations
Double bookkeeping is a term introduced by Eugen Bleuler to describe a fundamental feature of schizophrenia where psychotic reality can exist side by side with shared reality even when these realities seem mutually exclusive. Despite increasing theoretical interest in this phenomenon over the recent years, there are no empirical studies addressing this issue. We have, therefore, conducted a...
arXiv Preprint Archive
August 28, 2024
Prakash Chandra Kavi, Gorka Zamora-López, Daniel Ari Friedman
preprint
The emergence of cognition requires a framework that bridges evolutionary principles with neurocomputational mechanisms. This paper introduces the novel "thoughtseed" framework, proposing that cognition arises from the dynamic interaction of self-organizing units of embodied knowledge called "thoughtseeds" within the Global Workspace of consciousness. Leveraging foundational concepts from...
Schizophrenia Research
August 1, 2024
Josef Parnas, Karl Erik Sandsten
17 citations
Schizophrenia continues its resistance to the pathogenetic understanding. We believe that one of the reasons is an oblivion of schizophrenia's characteristic Gestalt expressive of its psychopathological structure. In this article we argue for a crucial role of disorders of selfhood in the constitution of this Gestalt. First, we present a phenomenological account of the self. This is followed by...
arXiv Preprint Archive
July 25, 2024
Robert Worden
preprint
It has been proposed that there is a wave excitation in animal brains, whose function is to represent three-dimensional space around the animal as a working spatial memory. After surveying the evidence supporting the hypothesis, I discuss ways in which it can be tested. There are many ways to investigate it, theoretically and experimentally. They include connectome studies, computational...
arXiv Preprint Archive
July 9, 2024
Joseph Bodenheimer, Paul Bogdan, Sérgio Pequito et al.
preprint
Understanding the neural mechanisms underlying the transitions between different states of consciousness is a fundamental challenge in neuroscience. Thus, we investigate the underlying drivers of changes during the resting-state dynamics of the human brain, as captured by functional magnetic resonance imaging (fMRI) across varying levels of consciousness (awake, light sedation, deep sedation,...
Frontiers in Psychology
June 3, 2024
Darius Parvizi-Wayne, Lars Sandved-Smith, Riddhi J. Pitliya et al.
20 citations
Flow has been described as a state of optimal performance, experienced universally across a broad range of domains: from art to athletics, gaming to writing. However, its phenomenal characteristics can, at first glance, be puzzling. Firstly, individuals in flow supposedly report a loss of self-awareness, even though they perform in a manner which seems to evince their agency and skill....
Neuropsychopharmacology
June 1, 2024
Conor H. Murray, Joel Frohlich, Connor J Haggarty et al.
30 citations
Neural complexity correlates with one's level of consciousness. During coma, anesthesia, and sleep, complexity is reduced. During altered states, including after lysergic acid diethylamide (LSD), complexity is increased. In the present analysis, we examined whether low doses of LSD (13 and 26 µg) were sufficient to increase neural complexity in the absence of altered states of consciousness. In...