The Doctrine of Concordance is the implicit assumption that cognitive processes, behavior, and phenomenological experience are highly correlated (Tulving, 1989). Tulving challenged this assumption, pointing to domains in which conscious experience did not accompany a particular measured cognitive process and to situations in which consciousness did not correlate with the observable behavior....
Recent years have seen growing interest in the use of metrics inspired by complexity science for the study of consciousness. Work in this field has shown remarkable results in discerning conscious from unconscious states, and in characterizing states of altered conscious experience following psychedelic intake as involving enhanced complexity. Here, we study the relationship between complexity...
Although substantial progress has been made in the last three decades towards our understanding of how general anesthetics (GAs) act at the molecular level, much less is known about how GAs cause loss of consciousness at the level of neuronal networks. The role of thalamus as an important brain region in anesthetic-induced hypnosis is relatively well established, but the specific roles of...
Nursing students are at risk for traumatic stress, but current treatments have limited benefits. Regenerating Images in Memory (RIM) is a verbal psychotherapeutic approach to help people safely re-experience troubling memories, then integrate them into meaningful life narratives. RIM's developers propose a mechanism of action based on nonconscious processes like emotional processing and body...
Much of high-level cognition appears inaccessible to consciousness. Countless studies have revealed mental processes-like those underlying our choices, beliefs, judgments, intuitions, etc.-which people do not notice or report, and these findings have had a widespread influence on the theory and application of psychological science. However, the interpretation of these findings is uncertain....
Quantum theories have long sought to explain conscious experience, yet their biggest challenge is not conceptual but methodological. A critical gap remains: the lack of statistical tools capable of empirically testing these theories against objective reality. This study introduces and formalizes the Q of Fisher-Escolà distribution, the first statistical model to integrate quantum and classical...
This study aimed at summarizing the clinical and neuroimaging features of patients with claustrum sign, so as to enhance the understanding of this imaging feature and explore its clinical significance. Clinical data from 20 patients with claustrum sign were collected. The clinical characteristics, neuroimaging evolution, and outcomes were analyzed. This cohort included 14 males and 6 females...
Depression, a global health concern with significant implications for suicide rates, remains challenging to treat effectively with conventional pharmacological options. The existing pharmaceutical interventions for these illnesses need daily dosing, are accompanied by various adverse effects, and may exhibit limited efficacy in certain cases. However, hope emerges from an unlikely...
5-MeO-DMT is a short-acting psychedelic that is anecdotally reported to induce a radical disruption of the self and a paradoxical quality of aroused, waking awareness that is nevertheless devoid of any specific perceptual contents. Here, we conducted an exploratory observational study of the phenomenological and neuronal effects of this compound. We collected micro-phenomenological interviews,...
Interest in the therapeutic effects of classical psychedelics has risen recently. However, little epidemiological knowledge exists about the use of classical psychedelics in Scandinavian countries. Additionally, there is a limited understanding of what factors drive self-reported improvement in wellbeing. The aim of this study was to investigate the relationship between the use of classical...