Of nine studies in vitro, six have indicated some degree of induced chromosomal breakage after exposure to LSD; three failed to confirm these results. The damage, when found, was generally of the chromatid type, arising during or after DNA synthesis. This damage, with one exception, was the result of concentrations of drug and durations of exposure which could not be achieved in humans with...
Thin titanium films have been bombarded with low energy (350 eV) deuterium ions at high current density (0.2-0.4 mA.cm2) to investigate the reported occurrence of nuclear reactions at ambient temperatures in deuterium charged metals. A silicon charged particle detector was used to search for charged particles produced by such reactions. Evidence is reported for the detection of hydrogen...
The use of LSD in the treatment of alcoholism has led to many claims concerning the drug's efficacy. Efforts to verify these reports in controlled studies have been difficult because of the unique effects of LSD. Despite this formidable methodological obstacle a number of investigations have been carried out. A critique of these is presented followed by our own research experience in a...
A wide variety of acute and chronic psychiatric symptoms have been seen in patients taking lysergic acid diethylamide (LSD).1We report a case of particular interest because the patient developed focal neurologic signs. Patient Summary A 14-year-old boy with no previous history of epilepsy, cardiovascular or neurological disease, or head trauma was hospitalized because of a short generalized...
It is well recognized that LSD (lysergide) can give serious adverse reactions, including suicide and prolonged psychosis; Smart and Bateman (1967) have reviewed the subject thoroughly. However, examples reported refer largely to cases where the LSD was self-administered. Medical case reports usually cover small case numbers, and publication may be determined by high adverse reaction rates....
. This pilot study evaluated data accumulated in the medical charts of patients at the NPI-UCLA who had been hospitalized because of psychiatric disorders connected with LSD use, between March 1965 and March 1967. We explored the characteristics of the patients and families by reviewing (1) demographic data, (2) patient drug history, (3) information about family interaction, and (4) the...
A total of 31 investigations involving 1,105 patients, on the effect of LSD in the treatment of alcoholics are reviewed. There were 13 single large-dose studies without controls, 5 such studies with controls, 4 studies of multiple low-dose LSD without controls, 3 multiple low-dose studies with controls, and 6 miscellaneous investigations that did not fit any of these categories. Single doses...
The fruiting bodies of C.laeve are several cm across, roundish, latercoalescing, soft and separable from the substrate.The colour is variable, brownish, light brownish-gray yellow to a gray brownwith a whitish, samewhat hairy margin.Upper surface smooth often cracked.Basidia 25-40-90 X 45.:_9 fl; spores obovate, sometimes slightly bent at the base 7-9-r2 X 45-7 fl (Bourd.and Galz.).In the...
A follow-up survey of 247 persons who received d-lysergic acid diethylamide (LSD) in either an experimental (nonmedical) or Psychotherapeutic setting was made to determine the lasting effects, if any, related to use of the drug. Information was collected from each by a structured interview and self-administered questionnaire. Some subsequent nonmedical use of LSD was reported by 23%, who...