Carotid Artery Obstruction Following LSD Capsule Ingestion
Archives of Internal Medicine February 1, 1971 DOI: 10.1001/archinte.1971.00310140118016 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | 14-year-old boy |
| Intervention | LSD |
| Dose | four LSD capsules |
| Topics | LSD |
| Keywords | Blood pressure Epilepsy Respiratory rate Unconsciousness Anesthesia Ingestion Heart rate Medical history Vital signs Physical examination Surgery |
| Citations | 37 |
| Key findings | LSD ingestion can trigger a generalized seizure with focal neurologic signs in a previously healthy adolescent. |
Abstract
A wide variety of acute and chronic psychiatric symptoms have been seen in patients taking lysergic acid diethylamide (LSD).1We report a case of particular interest because the patient developed focal neurologic signs. Patient Summary A 14-year-old boy with no previous history of epilepsy, cardiovascular or neurological disease, or head trauma was hospitalized because of a short generalized seizure characterized by eye rolling, clonic and tonic movements, and loss of consciousness. For one month prior to admission, his mother had noted episodes of elation and drowsiness. Family history was unremarkable. A history obtained from four of his companions revealed that the patient had taken four LSD capsules shortly before the seizure. No other capsules were found. Physical examination revealed a well-developed boy, mildly lethargic and restless. The blood pressure was 102/70 mm Hg; pulse rate, 88 beats per minute and regular; respiratory rate, 16 per minute; and temperature 100.6
Comparable studies
Other case reports and case series on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA | 1991 | Case study | n = 2 |
| Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness | 1957 | Case series | |
| Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally | 1975 | Case series | n = 8 |
| Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... | 2022 | Case series | |
| Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion | 1996 | Case series | n = 3 |
Citations in the library
Cited by 3
- Carotid Artery Occlusion Following Ingestion of LSD Stroke March 1, 1974
- Perceived Risk of Trying Lysergic Acid Diethylamide in the United States from 2015 to 2019: Are Americans Assessing Lysergic Acid Diethylamide's Risk Profile More Favorably? Psychedelic Medicine June 1, 2024
- Lysergic Acid Diethylamide (LSD) and the Heart: Exploring the Potential Impacts of LSD on Cardiovascular Function. Cureus July 1, 2025