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Carotid Artery Obstruction Following LSD Capsule Ingestion

Jack D. Sobel

Archives of Internal Medicine February 1, 1971 DOI: 10.1001/archinte.1971.00310140118016 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population 14-year-old boy
Intervention LSD
Dose four LSD capsules
Topics LSD
Keywords Blood pressure Epilepsy Respiratory rate Unconsciousness Anesthesia Ingestion Heart rate Medical history Vital signs Physical examination Surgery
Citations 37
Key findings LSD ingestion can trigger a generalized seizure with focal neurologic signs in a previously healthy adolescent.

Abstract

A wide variety of acute and chronic psychiatric symptoms have been seen in patients taking lysergic acid diethylamide (LSD).1We report a case of particular interest because the patient developed focal neurologic signs. Patient Summary A 14-year-old boy with no previous history of epilepsy, cardiovascular or neurological disease, or head trauma was hospitalized because of a short generalized seizure characterized by eye rolling, clonic and tonic movements, and loss of consciousness. For one month prior to admission, his mother had noted episodes of elation and drowsiness. Family history was unremarkable. A history obtained from four of his companions revealed that the patient had taken four LSD capsules shortly before the seizure. No other capsules were found. Physical examination revealed a well-developed boy, mildly lethargic and restless. The blood pressure was 102/70 mm Hg; pulse rate, 88 beats per minute and regular; respiratory rate, 16 per minute; and temperature 100.6

Comparable studies

Other case reports and case series on LSD, most cited first.

Study Year Design Participants
Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA 1991 Case study n = 2
Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness 1957 Case series
Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally 1975 Case series n = 8
Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... 2022 Case series
Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion 1996 Case series n = 3

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