This study was undertaken to examine the possible cytologic action of LSD-25, lysergic acid diethylamide, on nervous tissue. Organotypic cultures of mouse cerebellum were exposed to LSD in their nutrient medium for periods up to 53 hours. Light-microscopically, at a dose of 10-3 M, coarse granules developed in the cytoplasm of mature neurons and in the cytoplasm of cells in the outgrowth...
The results on the Halstead-Reitan neuropsychological battery were compared for a group of 20 LSD users and a normal control group matched for age, sex, education, and intelligence. Only one of 20 variables was significantly different at the 5 per cent level and this was thought to be due to chance. Thus, it was concluded that there was no difference between the two groups. A further comparison...
Journal Article The Use of Music in Psychedelic (LSD) Psychotherapy Get access Helen L. Bonny, Helen L. Bonny Search for other works by this author on: Oxford Academic PubMed Google Scholar Walter N. Pahnke Walter N. Pahnke Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Music Therapy, Volume 9, Issue 2, Summer 1972, Pages 64–87,...
Music and LSD: An Empirical Study Get access Charles T. Eagle Charles T. Eagle Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Music Therapy, Volume 9, Issue 1, Spring 1972, Pages 23–36, https://doi.org/10.1093/jmt/9.1.23 Published: 01 March 1972
A 22-year-old student killed a stranger during a psychotic reaction precipitated by lysergic acid diethylamide. With the exception of another bad trip, he had not been psychotic previously and showed no evidence of psychosis during four years of follow-up treatment.
To the Editor.— Friedman and Hirsch's article, "Extreme Hyperthermia after LSD Ingestion," (217:1549-1550, 1971) should be interpreted with caution. The case report of a hyperactive, verbally unresponsive patient with mildly elevated blood pressure, increased heart rate, and slightly dilated and reactive pupils is consistent with amphetamine as well as LSD overdose. The amnesia for the episode...
Hyperthermia is a known effect of lysergic acid diethylamide (LSD). This is, to our knowledge, the first recorded instance of life-threatening hyperthermia (106.4 F [41.3 C] axillary) in man, following the use of LSD, and may have been dose-related. The hyperthermia was rapidly reversed by alcoholic-ice soaks, hallucinations ended about 18 hours later, and the patient recovered without obvious...
SummaryA single ip injection of 25, 50, or 100 μg of LSD (lysergic acid diethylamide)/100 g of body weight into female rats on the morning of proestrus significantly decreased serum prolactin levels, and prevented the normal rise observed in control rats on the afternoon of proestrus. The 100-μg dose of LSD produced a significantly greater decrease in serum prolactin than the 25-μg dose. This...
Three patients with toxic psychosis associated with LSD ingestion responded dramatically to a short series of unilateral ECTs after more conservative measures had been unsuccessful. The conservative measures consisted of medication, psychotherapy, and therapeutic milieu. The author recommends ECT for the "bad trip" from LSD that does not remit rapidly.
This paper reports the findings of four exploratory studies in which the effects of lysergic acid diethylamide tartrate (LSD-25) on social behaviors were measured using the Bales Interaction Process Analysis technique. The interaction of four four-person continuing groups, including a group of reformatory inmates, two groups of alcoholics, and a group of chronic schizophrenics, was examined in...