Of nine studies in vitro, six have indicated some degree of induced chromosomal breakage after exposure to LSD; three failed to confirm these results. The damage, when found, was generally of the chromatid type, arising during or after DNA synthesis. This damage, with one exception, was the result of concentrations of drug and durations of exposure which could not be achieved in humans with...
Based on the frequently reported similarities between creative and psychedelic (drug-induced, consciousness-expansion) experiences, a preliminary study was conducted to explore the effects of psychedelic agents (LSD-25, mescaline) on creative problem-solving ability. Twenty-seven professionally employed males were given a single psychedelic experience in 1 of 7 small groups ( ns = 3 or 4)...
Since the discovery of d-lysergic acid diethylamide (LSD-25) in 1943, a voluminous literature has accumulated concerning its effects on a variety of animals, including man. Despite the mass of published reports, definitive evidence is generally lacking, particularly with regard to the subjective and behavioral effects both during and subsequent to the LSD induced state. It is well established...