A Morphologic Study of the Effects of LSD on Neurons in Cultures of Cerebellum
Journal of Neuropathology & Experimental Neurology July 1, 1972 Walter Hendelman 14 citations
This study was undertaken to examine the possible cytologic action of LSD-25, lysergic acid diethylamide, on nervous tissue. Organotypic cultures of mouse cerebellum were exposed to LSD in their nutrient medium for periods up to 53 hours. Light-microscopically, at a dose of 10-3 M, coarse granules developed in the cytoplasm of mature neurons and in the cytoplasm of cells in the outgrowth...