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Default mode network research published in 2025

Page 2 of 5: studies 21 to 40 of 82, newest first. Back to the default mode network overview

Studies

Immediate and sustained effects of acupuncture on the default mode network

Revista Brasileira de Psiquiatria September 29, 2025 Xiaotong Wang, Tao Huang, H. Lei et al.

Objective: To investigate, using functional magnetic resonance imaging (fMRI) techniques, the immediate and sustained effects of acupuncture on functional connectivity (FC) within the default mode network (DMN) and external FC. Methods: Thirty healthy participants received acupuncture needle stimulation at Baihui (GV20) and Yintang (GV29) and underwent resting-state fMRI scans in three phases:...

Meditation, psychedelics, and brain connectivity: A randomized controlled resting-state fMRI study of N,N-dimethyltryptamine and harmine in a meditation retreat

Universität Zürich, ZORA September 29, 2025 Klemens Egger, Daniel Meling, Firuze Polat et al.

Both meditation and psychedelics are widely studied for their therapeutic potential in mental health. Recent research suggests potential synergies between mindfulness practice and psychedelics, though empirical studies have primarily focused on psilocybin. This study investigates the distinct and combined effects of mindfulness practice and an ayahuasca-inspired formulation containing...

Exploring aperiodic, complexity and entropic brain changes during non-ordinary states of consciousness

arXiv (Cornell University) September 23, 2025 Victor Oswald, Karim Jerbi, Corine Sombrun et al. preprint

Non-ordinary states of consciousness (NOC) provide an opportunity to experience highly intense, unique, and perceptually rich subjective states. The neural mechanisms supporting these experiences remain poorly understood. This study examined brain activity associated with a self-induced, substance-free NOC known as Auto-Induced Cognitive Trance (AICT). Twenty-seven trained participants...

DOI: 10.48550/arxiv.2509.19254 (opens in new tab) Full text (opens in new tab) Default mode network Discriminative model Electroencephalography Consciousness +15

Characterization of the hemodynamic response function in default mode network subregions for task-evoked negative BOLD responses

bioRxiv September 19, 2025 Hengda He, B. G. Yazdi, Amir Sedaghat et al. preprint

While the hemodynamic response function (HRF) of the positive blood oxygenated level dependent (BOLD) signal is well characterized in the functional magnetic resonance imaging (fMRI) field, studies investigating the shape and properties of the negative BOLD HRF, often observed in the default mode network (DMN) regions, are rare. In this study, we first investigated the linearity of the...

Default mode network connectivity contributes the augment effect stress recovery by natural viewing

Neurobiology of Stress September 12, 2025 Zi-Ni Chen, Chanyu Wang, T. Toulopoulou et al.

The psychological benefits of exposure to natural environments are well established. However, whether simply viewing nature images produce similar restorative effects and the brain mechanisms involved remain unclear. For study purposes, we recruited 131 healthy university students and randomly assigned them to a nature image viewing group (NG) or a city image viewing group (CG), with 49...

Acupuncture effect on brain default mode network connectivity in breast cancer patients with hot flashes: A randomized controlled trial.

European Journal of Cancer September 12, 2025 Zhuo-Nan Wang, Gui-Hua Tian, Jie-Rui Ding et al.

OBJECTIVE To use functional MRI to assess the effect of acupuncture on brain resting-state functional connectivity in breast cancer patients with hot flashes. METHODS A total of 24 breast cancer patients experiencing hot flashes (BC-HF) underwent 5 weeks of acupuncture treatment and follow-up at 4-6 months after therapy. The control groups included 35 patients with breast cancer without hot...

Machine Learning-Based Alexithymia Assessment Using Resting-State Default Mode Network Functional Connectivity

Sensors September 12, 2025 Kei Suzuki, Midori Sugaya

Alexithymia is regarded as one of the risk factors for several prevalent mental disorders, and there is a growing need for convenient and objective methods to assess alexithymia. Therefore, this study proposes a method for constructing models to assess alexithymia using machine learning and electroencephalogram (EEG) signals. The explanatory variables for the models were functional connectivity...

DOI: 10.3390/s25175515 (opens in new tab) Full text (opens in new tab) Default mode network Alexithymia Source localization Electroencephalogram +1

Social Smiling and Laughter Are Linked to Enhanced Functional Brain Connectivity in Young Infants’ Default Mode Network

Developmental Psychobiology September 1, 2025 O. Allison, Caroline M. Kelsey, Tobias Grossmann

Abstract The current study used functional near‐infrared spectroscopy (fNIRS) to investigate whether and how individual differences in positive social engagement among 5‐month‐old (N = 109; N = 35 final sample) infants relate to variability in functional connectivity in the human brain's Default‐Mode Network (DMN). Neuroimaging results showed that on average infants displayed greater functional...

Neural variability in the default mode network compresses with increasing belief precision during Bayesian inference

Cerebral Cortex September 1, 2025 Alexander Skowron, Julian Q. Kosciessa, Robert Lorenz et al.

Abstract To make optimal decisions, intelligent agents must learn latent environmental states from discrete observations. Bayesian frameworks argue that integration of evidence over time allows us to refine our state belief by reducing uncertainty about alternate possibilities. How is this increasing belief precision during learning reflected in the brain? We propose that temporal neural...

Effects of Tummo Meditation and Niguma Yoga on Brain Activity.

Hawai'i journal of health & social welfare September 1, 2025 Ira D Zunin, Alexander J Ring, Audrey M Sakamoto et al.

Hatha yoga, Qigong, Tai Chi, all ancient practices of the mind, continue to be studied and recognized for their mental and spiritual benefits. However, Tummo meditation and Niguma yoga, ancient practices with origins in the 8th and 11th centuries from the Himalayan Vajrayana tradition, remain obscure and have yet to be disseminated and studied. Previously only practiced by Vajrayana monks...

Default mode network connectivity predicts individual differences in long-term forgetting: Evidence for storage degradation, not retrieval failure

bioRxiv August 24, 2025 Yinan Xu, C. Prat, Florian Sense et al. preprint

Despite the importance of memories in everyday life and the progress made in understanding how they are encoded and retrieved, the neural processes by which declarative memories are maintained or forgotten remain elusive. Part of the problem is that it is empirically difficult to measure the rate at which memories fade, even between repeated presentations of the source of the memory. Without...

Functional coupling of the lateral prefrontal cortex and the default mode network predicts performance in mental rotation

Imaging Neuroscience August 14, 2025 Radek Ptak, Naz Doganci, Emilie Marti et al.

Abstract Mental transformations, such as mental rotation, rely on motor representations and engage neural processes similarly to physical actions. Neuroimaging studies reveal that mental rotation activates the occipito-parietal cortex and motor-related areas, with differences based on whether stimuli are bodily or non-bodily. These findings emphasize the role of frontoparietal networks in...

Oxytocin and the Default Mode Network: New Insights into Attachment and Self-Referential Processing

Galen Medical Journal August 5, 2025 Shingo Ueda

Recent advances in neuroscience have revealed a significant interplay between the neuropeptide oxytocin and the brain’s Default Mode Network (DMN), suggesting a pivotal role in modulating attachment and self-referential processing. This review synthesizes current findings from neuroimaging, behavioral studies, and clinical research to explore the “oxytocin-DMN axis” and its impact on social...

A dynamic framework of brain functional patterns shaped by spontaneous thoughts beyond the default mode network.

Scientific Reports August 4, 2025 Sandrine Cremona, Achille Gillig, Emmanuel Mellet et al.

Cognitive functions emerge from the dynamic interplay of distributed, large-scale brain networks. Functional connectivity (FC) reflects stable brain organization and general cognitive abilities, while also capturing individual variations in transient cognitive states. Analyzing data from 1,717 participants, we show that rich and diverse spontaneous thought profiles align with distinct patterns...

Effects of white ginseng on reducing stress and tension by enhancing default mode network connectivity: A randomized, double-blinded placebo-controlled clinical trial

Journal of Ginseng Research August 1, 2025 Youngeun Shim, Young-Seob Lee, Yejin Kim et al.

Background Recent research has increasingly focused on the potential role of white ginseng (Panax ginseng Meyer, PGC) in alleviating psychological conditions. This study aims to evaluate the efficacy and safety of PGC in reducing stress and tension over a 12-week period, employing a randomized, double-blind, placebo-controlled trial design. Methods A total of 86 participants reporting...

Default mode network synchrony reflects shared understanding

Current Opinion in Behavioral Sciences August 1, 2025 Tal Ohad, Yohay Zvi, Y. Yeshurun

The default mode network (DMN) has been linked to self-reflection and theory of mind, suggesting that it facilitates understanding others by reflecting on ourselves. This raises the question of whether shared (synchronized) DMN responses are associated with mutual understanding. The current paper reviews studies on DMN synchronization during shared understanding of external events, regarding...

Transfer of motor learning is associated with patterns of activity in the default mode network

PLoS Biology August 1, 2025 A. Rezaei, Corson N. Areshenkoff, Daniel J. Gale et al.

An often-desired feature of motor learning is that it generalizes to untrained scenarios. Yet, how this is supported by brain activity remains poorly understood. Here we show, using human functional MRI and a sensorimotor adaptation task involving the transfer of learning from the trained to untrained hand, that the transfer phase of adaptation re-instantiates a highly similar large-scale...

Breath-Focused Mindfulness and Compassion Training in Parent-Child Dyads: Pilot Intervention Study.

JMIR Formative Research July 17, 2025 Satish Jaiswal, Jason Nan, Seth Dizon et al. 5 citations

Depression in children is a concerning societal issue and can be associated with poor academic performance, school dropout, and poor overall quality of life. Additionally, child depression is often associated with parallel stress and depression in parents. This scenario highlights the urgent need for the development and implementation of accessible and scalable solutions that may cobenefit...

Altered glucose metabolism in default mode network and prefrontal circuit in patients with Kallmann syndrome

EJNMMI Research July 11, 2025 Chun-Qing Zhou, Xueying Wang, Mei-Chao Men et al.

This study delineates brain metabolic signatures underlying neuroendocrine-psychosocial interactions in Kallmann syndrome (KS), a rare genetic disorder characterized by congenital hypogonadism and anosmia. In this prospective case-control study, 30 KS patients and 30 matched healthy controls (HCs) underwent brain [18F]FDG PET scans, sex hormone assays, and standardized neuropsychological...

Alterations of the default mode network, salience network, and frontoparietal network in non-problematic Internet use and their association with mood regulation: from an internet literacy perspective

Frontiers in Neuroscience July 1, 2025 Mami Shibata, Kosuke Tsurumi, Kei Kobayashi et al.

IntroductionAlthough a number of neuroimaging studies on problematic internet use (PIU) have been conducted, few studies on non-problematic internet use (non-PIU) are available; therefore, the influences of non-PIU on brain function are unclear. Resting-state functional connectivity (rsFC) could be an appropriate tool to investigate subclinical samples, such as non-PIU, to capture the...