Developmental Psychobiology
September 1, 2025
O. Allison, Caroline M. Kelsey, Tobias Grossmann
Abstract The current study used functional near‐infrared spectroscopy (fNIRS) to investigate whether and how individual differences in positive social engagement among 5‐month‐old (N = 109; N = 35 final sample) infants relate to variability in functional connectivity in the human brain's Default‐Mode Network (DMN). Neuroimaging results showed that on average infants displayed greater functional...
Developmental Psychobiology
July 2022
Kaytlin L Constantin, Rachel L Moline, Rebecca Pillai Riddell et al.
Needle procedures are common throughout childhood and often elicit distress in children and parents. Heart rate variability (HRV), as an index of emotion regulation, can inform both self-regulatory and co-regulatory processes. Mindfulness may serve to regulate distress; however, no research has studied mindfulness or parent and child regulatory responding concurrently during venipuncture....
Developmental Psychobiology
January 2018
Carlos Coronel-Oliveros, Renny Pacheco-Calderón
Schizophrenia is a complex neuropsychiatric disorder characterized by hallucinations, delusions, anhedonia, flat affect and cognitive impairments. The aim of this study was to propose a prenatal treatment with ketamine, a psychedelic drug that acts as a non-competitive inhibitor of glutamate NMDA receptors, as a neurodevelopmental animal model of schizophrenia. The drug was applied (i.m. 60...
Developmental Psychobiology
July 1, 2014
Brian J. Piper, Christina S. Henderson, Jerrold S. Meyer
2 citations
AbstractIntermittent MDMA pretreatment blocked the reductions in serotonin transporter (SERT) binding induced by an MDMA binge in a prior study in adolescent male rats. The objective of this investigation was to determine if the physiological, behavioral, and neurochemical responses to MDMA are sexually dimorphic. Female Sprague–Dawley rats received MDMA (10 mg/kg × 2) or Saline on every fifth...
Developmental Psychobiology
June 15, 2013
Jennifer L. Cobuzzi, Kayla Siletti, Zachary E. Hurwitz et al.
15 citations
Preclinical work indicates that adolescent rats appear more sensitive to the rewarding effects and less sensitive to the aversive effects of abused drugs. The present investigation utilized the conditioned taste aversion (CTA) design to measure the relative aversive effects of (±)3,4-methylenedioxymethamphetamine (MDMA; 0, 1.0, 1.8, or 3.2 mg/kg) in adolescent and adult Sprague-Dawley rats....
Developmental Psychobiology
2005
Brian J. Piper, Joseph B. Fraiman, Jerrold S. Meyer
71 citations
Previous research in our laboratory found that repeated exposure of adolescent rats to 3,4-methylenedioxymethamphetamine (MDMA) impaired working memory and reduced anxiety. The present experiment extended these findings by investigating the physiological, behavioral, and neurotoxic effects of a modified MDMA treatment regimen. Male Sprague-Dawley rats received 5 mg/kg of MDMA hourly for a...
Developmental Psychobiology
July 1, 1984
Michael E. Trulson, Gailyn A. Howell
5 citations
AbstractThe ontogeny of the behavioral effects of lysergic acid diethylamide (LSD) was examined in cats between the ages of 4 and 112 days postpartum. The kittens showed little LSD‐induced behavioral change prior to 14 days of age. By the age of 21 days, however, the kittens exhibited many of the behavioral signs characteristic of LSD‐induced behaviors in adult cats. These behaviors include...