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Default mode network research published in 2025

Page 4 of 5: studies 61 to 80 of 82, newest first. Back to the default mode network overview

Studies

The Default Mode Network and Visual Network Functional Connectivity Changes in Noise‐Induced Hearing Loss Patients: A Resting‐State fMRI Study

Brain and Behavior April 1, 2025 Wei Lian, Lei Zhang, Ai-Jie Wang et al.

Hearing loss affects communication and hinders personal attention and cognitive ability. We hypothesized that noise‐induced hearing loss (NIHL) patients during long‐term noise exposure may result in multimodal plastic changes in the nonauditory central nervous system.

The Journey of the Default Mode Network: Development, Function, and Impact on Mental Health

Biology April 1, 2025 F. R. Azarias, Gustavo Henrique Doná Rodrigues Almeida, Luana Felix de Melo et al.

Simple Summary The Default Mode Network (DMN) is a brain network that becomes active when the brain is at rest. It is crucial for processes like self-reflection, emotional processing, social interaction, and mental exploration. Research has shown that the DMN is not exclusive to humans but is also found in non-human animals, suggesting its evolutionary importance across species. The DMN plays a...

Default Mode Network Functional Connectivity As a Transdiagnostic Biomarker of Cognitive Function.

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging April 1, 2025 Vaibhav Tripathi, Ishaan Batta, Andre Zamani et al. 23 citations

The default mode network (DMN) is intricately linked with processes such as self-referential thinking, episodic memory recall, goal-directed cognition, self-projection, and theory of mind. In recent years, there has been a surge in the number of studies examining its functional connectivity, particularly its relationship with frontoparietal networks involved in top-down attention, executive...

Enhancing Equanimity With Noninvasive Brain Stimulation: A Novel Framework for Mindfulness Interventions.

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging April 1, 2025 Brian Lord, John J B Allen, Shinzen Young et al. 4 citations

Mindfulness has gained widespread recognition for its benefits for mental health, cognitive performance, and well-being. However, the multifaceted nature of mindfulness, which encompasses elements such as attentional focus, emotional regulation, and present-moment awareness, complicates its definition and measurement. A key component that may underlie its broad benefits is equanimity-the...

Initial evidence for neural correlates following a therapeutic intervention: altered resting state functional connectivity in the default mode network following attention training technique

Frontiers in Psychiatry March 6, 2025 T. Müller, Svenja Krug, Özlem Kayali et al.

Introduction The Attention Training Technique (ATT) is a psychotherapeutic intervention in Metacogntive Therapy (MCT) and aims at reducing maladaptive processes by strengthening attentional flexibility. ATT has demonstrated efficacy in treating depression on a clinical level. Here, we evaluated ATT at the neural level. We examined functional connectivity (FC) of the default mode network (DMN)....

White matter integrity of default mode network after a 3-month aerobic dance program in patients with amnestic mild cognitive impairment: a secondary analysis of a randomized clinical trial.

Quantitative imaging in medicine and surgery March 3, 2025 Han Wu, Yi Zhu, Xi Yang et al. 2 citations

Exercise is an effective non-pharmacological strategy to enhance cognitive function in individuals with mild cognitive impairment (MCI). Our previous studies confirmed that aerobic dance can increase the amplitude of low-frequency fluctuations (LFF) in bilateral fronto-temporal, entorhinal, anterior cingulate, and para-hippocampal cortices. However, its effects on structural connections remain...

DOI: 10.21037/qims-24-1212 (opens in new tab) Full text (opens in new tab) Default mode network Aerobic dance Cognitive performance Structural connection dmn

Functional connectivity of subsystems of the default-mode network in patients with early psychotic symptoms

Neuroimage: Reports March 1, 2025 Nicky Lute, I. Lemmers-Jansen, L. Krabbendam et al.

Resting-state connectivity of the default-mode network (DMN) is aberrant in patients with chronic psychotic disorders as well in individuals with early stage psychosis. Studies of the DMN in healthy volunteers revealed that the DMN comprises several subnetworks. However, it is not yet clear if connectivity between and within these DMN subnetworks is aberrant in patients with early psychotic...

Alpha-Frequency Stimulation Enhances Synchronization of Alpha Oscillations with Default Mode Network Connectivity

eNeuro March 1, 2025 Yi-Jia Ma, Joshua A. Brown, Chao-Wen Chen et al.

Alpha (8–12 Hz) oscillations and default mode network (DMN) activity dominate the brain's intrinsic activity in the temporal and spatial domains, respectively. They are thought to play crucial roles in the spatiotemporal organization of the complex brain system. Relatedly, both have been implicated, often concurrently, in diverse neuropsychiatric disorders, with accruing electroencephalogram...

Severity of anhedonia is associated with hyper-synchronization of the salience-default mode network in non-clinical individuals: a resting state EEG connectivity study

Journal of Neural Transmission February 15, 2025 Claudio Imperatori, Giorgia Allegrini, Aurelia Lo Presti et al.

Anhedonia is a core transnosographic symptom in several neuropsychiatric disorders. Recently, the Triple Network (TN) model has been proposed as a useful neurophysiological paradigm for conceptualizing anhedonia, providing new insights to clinicians and researchers. Despite this, the relationship between the functional dynamics of TN and the severity of anhedonia has been relatively...

Dynamical repertoire of brain networks in mindfulness cognitive behavioural therapy during rumination: A randomized controlled trial

medRxiv February 7, 2025 Jakub Vohryzek, Anne Maj van der Velden, Willem Kuyken et al. 1 citation preprint

BACKGROUND: Depression is a prevalent and debilitating affective disorder characterised by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for recurrent depression developed specifically to target rumination and recurrence risk by training metacognitive awareness and adaptive attention, emotion and self-regulation...

The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow

Nature Neuroscience January 28, 2025 Casey Paquola, Margaret Garber, Stefan Frässle et al. 58 citations

The default mode network (DMN) is implicated in many aspects of complex thought and behavior. Here, we leverage postmortem histology and in vivo neuroimaging to characterize the anatomy of the DMN to better understand its role in information processing and cortical communication. Our results show that the DMN is cytoarchitecturally heterogenous, containing cytoarchitectural types that are...

DOI: 10.1038/s41593-024-01868-0 (opens in new tab) Default mode network Cytoarchitecture Human brain Neuroimaging +3

Resting-state functional connectivity between the frontoparietal network and the default mode network is aberrantly increased in ankylosing spondylitis

BMC musculoskeletal disorders January 23, 2025 Dong Liu, Chu-Rong Lin, Bu-Dian Liu et al.

Lower back pain comprises the majority of the disease burden of patients with ankylosing spondylitis (AS), while the alterations of the large-scale brain networks could be implicated in the neuropathophysiology of pain. The frontoparietal network (FPN) is known as a pain modulation hub, with key nodes dorsolateral prefrontal cortex (dlPFC) and ventrolateral prefrontal cortex (vlPFC)...

Resting-state BOLD temporal variability of the default mode network predicts spontaneous mind wandering, which is negatively associated with mindfulness skills.

Frontiers in Human Neuroscience January 22, 2025 Sara Sorella, Cristiano Crescentini, Alessio Matiz et al. 8 citations

Mind wandering (MW) encompasses both a deliberate and a spontaneous disengagement of attention from the immediate external environment to unrelated internal thoughts. Importantly, MW has been suggested to have an inverse relationship with mindfulness, a state of nonjudgmental awareness of present-moment experience. Although they are, respectively, associated with increased and decreased...

DOI: 10.3389/fnhum.2025.1515902 (opens in new tab) Full text (opens in new tab) Unprompted thoughts Spontaneous mind wandering Unwanted mental excursions Brain's resting activity +7

Catalyst for change: Psilocybin’s antidepressant mechanisms—A systematic review

Journal of Psychopharmacology January 20, 2025 Joshua Liebnau, Felix Betzler, André Kerber 10 citations

Background: Recent clinical trials suggest promising antidepressant effects of psilocybin, despite methodological challenges. While various studies have investigated distinct mechanisms and proposed theoretical opinions, a comprehensive understanding of psilocybin’s neurobiological and psychological antidepressant mechanisms is lacking. Aims: Systematically review potential antidepressant...

Uncovering Psychedelics: From Neural Circuits to Therapeutic Applications

Pharmaceuticals January 19, 2025 Marco Bonaso, Letizia Biso, Benedetta Zucchini et al. 13 citations

Psychedelics, historically celebrated for their cultural and spiritual significance, have emerged as potential breakthrough therapeutic agents due to their profound effects on consciousness, emotional processing, mood, and neural plasticity. This review explores the mechanisms underlying psychedelics’ effects, focusing on their ability to modulate brain connectivity and neural circuit activity,...

Lateralization of the Aberrant Amplitude of Low-Frequency Fluctuation within the Default Mode Network in Patients with Mild Cognitive Impairment.

Academic Radiology 2025 Yongjia Shao, Yan Li, Zijian Wang et al.

RATIONALE AND OBJECTIVES Alzheimer's disease (AD) is the most common pathogenesis of dementia, and mild cognitive impairment (MCI) is considered as the intermediate stage from normal elderly to AD. Early detection of MCI is an essential step for the timely intervention of AD to slow the progression of this disease. Different form previous studies in the whole-brain spontaneous activities, this...

Resting State Functional Connectivity of the Default Mode Network During Opioid Use and Cessation in Treatment‐Seeking Persons

European Journal of Neuroscience 2025 Jade Dandurand, Michael D. Stein, B. Surprenant et al.

Resting‐state functional connectivity analyses have been used to examine synchrony in neural networks in substance use disorders (SUDs), with the default mode network (DMN) one of the most studied. Prior research has generally found less DMN synchrony during use and greater synchrony during cessation, although little research has utilized this method with opioid use. This study examined resting...

Examining Insula–Default Mode Network Functional Connectivity and Its Relationship with Heart Rate Variability

Brain Science 2025 Marlene Nogueira, Juliana da Silva Magalhães, Adriana Sampaio et al.

Background: The Default Mode Network (DMN) is involved in self-referential and emotional processes, while the insula integrates emotional and interoceptive signals. Functional connectivity between the insula and the DMN is proposed to enhance these processes by linking internal bodily states with self-referential thoughts and emotional regulation. Heart Rate Variability (HRV), a measure of...

Resting-State Functional Connectivity Between the Cingulo-Opercular and Default Mode Networks May Explain Socioeconomic Inequalities in Cognitive Development.

Journal of cellular neuroscience 2025 Shervin Assari, Alexandra Donovan, Golnoush Akhlaghipour et al.

The Cingulo-Opercular Network (CON) is a crucial executive control network involved in regulating actions and facilitating higher-order cognitive processes. Resting-state functional connectivity between the CON and the Default Mode Network (DMN) plays a vital role in cognitive regulation, enabling the transition between internally focused and externally directed tasks. This study investigates...

DOI: 10.31586/jcn.2025.1241 (opens in new tab) Full text (opens in new tab) Default mode network Cingulo-opercular network Cognition Educational opportunities +2