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Galen Medical Journal

ISSN 2322-2379

2 papers in the library · 1 citation · publishing 2023-2025

Papers

The Effect of Mindfulness Interventions on the Sleep Quality of Pregnant Mothers in the Second and Third Trimesters of Pregnancy.

Galen Medical Journal January 1, 2023 Razieh Shamabadi, Mahboubeh Eslamzadeh, Elnaz Eskandarnia et al. 1 citation

Mindfulness training significantly improved sleep quality among pregnant women in their second and third trimesters. In a randomized clinical trial, 98 pregnant women were divided into an intervention group (50 women) receiving six 90-minute mindfulness sessions over two months and a control group (48 women) receiving routine care. Sleep quality and psychological measures (anxiety, stress, depression) were assessed before, after, and one month following the intervention. The mindfulness group showed meaningful improvements in sleep quality, and scores for anxiety, stress, and depression also changed significantly over the study period. Mindfulness interventions can be used to enhance psychological wellbeing and reduce anxiety and stress during pregnancy.

Oxytocin and the Default Mode Network: New Insights into Attachment and Self-Referential Processing

Galen Medical Journal August 5, 2025 Shingo Ueda

A review synthesizes evidence that oxytocin, a neuropeptide, interacts with the brain's Default Mode Network (DMN) to influence attachment and self-referential processing. Oxytocin appears to modulate intrinsic connectivity within the DMN, enhancing self-referential thought, social bonding, autobiographical memory, empathy, and social awareness. Dysregulation of this oxytocin-DMN axis may contribute to psychiatric disorders such as autism, social anxiety, and depression. The review evaluates the therapeutic potential of targeting oxytocin signaling to restore DMN functionality, integrating neuroimaging, behavioral, and clinical research to highlight the mechanistic links between hormonal modulation and intrinsic brain network dynamics.