Human Brain Mapping
May 1, 2018
Neda Kaboodvand, Lars Bäckman, Lars Nyberg et al.
The default mode network (DMN) involves interacting cortical areas, including the posterior cingulate cortex (PCC) and the retrosplenial cortex (RSC), and subcortical areas, including the medial temporal lobe (MTL). The degree of functional connectivity (FC) within the DMN, particularly between MTL and medial-parietal subsystems, relates to episodic memory (EM) processes. However, past...
Frontiers in Neurology
April 26, 2018
Benjamin T. Dunkley, Karolina Urban, Leodante Da Costa et al.
Concussion is a common form of mild traumatic brain injury. Despite the descriptor "mild," a single injury can leave long-lasting and sustained alterations to brain function, including changes to localized activity and large-scale interregional communication. Cognitive complaints are thought to arise from such functional deficits. We investigated the impact of injury on neurophysiological and...
Brain Connectivity
April 5, 2018
Deniz Vatansever, Anne E. Manktelow, Barbara J. Sahakian et al.
The default mode network (DMN) is typically associated with off-task internal mentation, or with goal-oriented tasks that require self-referential processing such as autobiographical planning. However, recent reports suggest a broader involvement of the DMN in higher cognition. In line with this view, we report global connectivity changes that are centered on the main DMN hubs of precuneus and...
Neural Plasticity
April 1, 2018
Emiliano Santarnecchi, Chiara Del Bianco, Isabella Sicilia et al.
Insomnia might occur as result of increased cognitive and physiological arousal caused by acute or long acting stressors and associated cognitive rumination. This might lead to alterations in brain connectivity patterns as those captured by functional connectivity fMRI analysis, leading to potential insight about primary insomnia (PI) pathophysiology as well as the impact of long-term exposure...
Schizophrenia Research
April 1, 2018
Susan Whitfield-Gabrieli, Adina S. Fischer, Angela Henricks et al.
Nearly half of patients with schizophrenia (SCZ) have co-occurring cannabis use disorder (CUD), which has been associated with decreased treatment efficacy, increased risk of psychotic relapse, and poor global functioning. While reports on the effects of cannabis on cognitive performance in patients with SCZ have been mixed, study of brain networks related to executive function may clarify the...
bioRxiv
March 22, 2018
Carl J. Hodgetts, Jonathan P. Shine, Huw Williams et al.
preprint
Young adult APOE -ε4 carriers show increased activity in posterior regions of the default mode network (pDMN), but how this is related to structural connectivity is unknown. Thirty young adults (half APOE -ε4 carriers, the other half APOE -ε3ε3/ε2ε3; mean age 20 years) were scanned using both diffusion and functional magnetic resonance imaging. Diffusion tractography was used to quantify the...
Journal of Neuroscience
March 19, 2018
Katrin H. Preller, Leonhard Schilbach, Thomas Pokorny et al.
75 citations
Distortions of self-experience are critical symptoms of psychiatric disorders and have detrimental effects on social interactions. In light of the immense need for improved and targeted interventions for social impairments, it is important to better understand the neurochemical substrates of social interaction abilities. We therefore investigated the pharmacological and neural correlates of...
Neuropsychologia
March 17, 2018
Tali R. Marron, Yulia Lerner, Ety Berant et al.
128 citations
Research on creativity shows that creative thinking entails both executive (controlled) and associative (spontaneous) processes. Yet standard creativity tasks cannot reliably isolate these two types of cognitive processes, making it difficult to understand the relation between the two and the roles of their corresponding brain networks in creative cognition. In this study we used a behavioral...
Neuroscience
March 8, 2018
Zheng Zhang, Delong Zhang, Zengjian Wang et al.
Previous studies have reported the essence of the sensory-based properties of human brain function, in which mental imagery is of great importance. In this study, we explored the association between the activities of two special regions, i.e., the primary visual area (PVA), which is the classically dominant sensory region, and the default mode network (DMN), which is the classical supra-sensory...
Neurological Sciences
March 6, 2018
ChunLei Wang, Yuan Pan, YanMei Liu et al.
Independent component analysis (ICA) is one of the most popular and valid methods to investigate the default mode network (DMN), an intrinsic network which attracts particular attention in amnestic mild cognitive impairment (aMCI). However, previous studies present inconsistent results regarding the topographical organization of the DMN in aMCI. Therefore, we conducted a quantitative,...
Journal of Neuroscience
February 13, 2018
Adam M Staffaroni, Jesse A. Brown, K. Casaletto et al.
The default mode network (DMN) supports memory functioning and may be sensitive to preclinical Alzheimer's pathology. Little is known, however, about the longitudinal trajectory of this network's intrinsic functional connectivity (FC). In this study, we evaluated longitudinal FC in 111 cognitively normal older human adults (ages 49–87, 46 women/65 men), 92 of whom had at least three task-free...
Social Cognitive and Affective Neuroscience
February 7, 2018
Sarah M. Tashjian, Diane Goldenberg, M. Monti et al.
Abstract Sleep suffers during adolescence and is related to academic, emotional and social behaviors. How this normative change relates to ongoing brain development remains unresolved. The default mode network (DMN), a large-scale brain network important for complex cognition and socioemotional processing, undergoes intra-network integration and inter-network segregation during adolescence....
International journal of chronic obstructive pulmonary disease
February 7, 2018
Xianwei Hu, Haibao Wang, Youhui Tu et al.
Background and objectives: Cognitive impairment is a common extrapulmonary comorbidity in COPD patients. The default mode network (DMN) plays a critical role in maintaining the normal activities of humans, and its function can be evaluated by resting state functional magnetic resonance imaging. The aim of this study was to investigate the correlations between cognition and function changes of...
Brain Imaging and Behavior
February 1, 2018
Carlos R Hernandez-Castillo, Jörn Diedrichsen, Erika Aguilar-Castañeda et al.
Several studies have suggested both a local and network reorganization of the sensorimotor system following amputation. Transplantation of a new limb results in a new shifting of cortical activity in the local territory of the transplanted limb. However, there is a lack of information about the reversibility of the abnormalities at the network level. The objective of this study was to...
Developmental Cognitive Neuroscience
January 31, 2018
David G. Weissman, R. Conger, R. Robins et al.
Experiencing poverty during childhood and adolescence may affect brain function. However, income is dynamic, and studies have not addressed whether income change relates to brain function. In the present study, we investigated whether intrinsic functional connectivity of default mode network (DMN) regions was influenced by mean family income and family income change. Parents of 68...
Journal of Neuroscience
January 31, 2018
John T. Arsenault, Natalie Caspari, Rik Vandenberghe et al.
A unifying function associated with the default mode network (DMN), which is more active during rest than under active task conditions, has been difficult to define. The DMN is activated during monitoring the external world for unexpected events, as a sentinel, and when humans are engaged in high-level internally focused tasks. The existence of DMN correlates in other species, such as mice,...
World neurosurgery
January 31, 2018
Yusuke Sakamoto, Sho Okamoto, Satoshi Maesawa et al.
Objective: Neurocognitive impairment is often reported in moyamoya disease. We aimed to detect default mode network (DMN) alterations using resting-state functional magnetic resonance imaging and their association with neurocognitive impairments. In addition, the influence of surgical treatment was individually evaluated. Methods: Seven patients with moyamoya disease underwent preoperative...
Psychiatry Research Neuroimaging
January 30, 2018
Friederike Gundel, Johanna Von Spee, Sabrina Schneider et al.
Mindfulness meditation as a therapeutic intervention has been shown to have positive effects on psychological problems such as depression, pain or anxiety disorders. In this study, we used functional near-infrared spectroscopy (fNIRS) to detect differences in hemodynamic responses of meditation experts (14 participants) and a control group (16 participants) in a resting and a mindfulness...
Frontiers in Aging Neuroscience
January 24, 2018
L. Huo, Rui Li, Pengyun Wang et al.
While the neural correlates of age-related decline in episodic memory have been the subject of much interest, the spontaneous functional architecture of the brain for various memory processes in elderly adults, such as immediate recall (IR) and delayed recall (DR), remains unclear. The present study thus examined the neural correlates of age-related decline of various memory processes. A total...
Behavioural Brain Research
January 15, 2018
Hilary A Marusak, Farrah Elrahal, Craig A Peters et al.
Interventions that promote mindfulness consistently show salutary effects on cognition and emotional wellbeing in adults, and more recently, in children and adolescents. However, we lack understanding of the neurobiological mechanisms underlying mindfulness in youth that should allow for more judicious application of these interventions in clinical and educational settings. Using multi-echo...