Frontiers in Neurology
September 1, 2026
Huan Yin, Xiaohong Guo, Yujun Gao et al.
Objective Dysfunction of the default mode network (DMN) is strongly linked to pain processing, as well as onset and progression of chronic pain disorders; however, its specific role in the pathogenesis of tension-type headache (TTH) remains incompletely understood. This study aims to explore the network homogeneity (NH) of the DMN in the pathophysiological mechanisms underlying TTH. Methods...
Frontiers in Neurology
August 24, 2026
Longyun Chen, Bencheng Wang, Ting Li et al.
Purpose To evaluate the association between an 8-week group Mindfulness-Based Cognitive Therapy (MBCT) program and changes in professional dementia caregiver burden, perceived stress, and patient neuropsychiatric symptoms. Methods This retrospective multi-method study included 94 professional dementia caregivers at a psychiatric hospital in China (intervention: n = 48; control: n = 46). The...
Frontiers in Neurology
April 23, 2026
Jing Cao, ZiYuan Wang, GeGe Lv et al.
Background Paclitaxel (PTX), a broad-spectrum anti-tumor drug, is extensively employed as a first-line chemotherapy for solid tumors, including lung and breast cancers. However, it induces chemotherapy-related pain and anxiety in over 53% of patients. S-ketamine, the S-enantiomer of ketamine, exerts rapid antidepressant effects. In this study, we established a PTX model to examine the effects...
Frontiers in Neurology
March 30, 2026
Jose E. Leon-Rojas, Guido Mascialino, Lizeth Vinueza Mera et al.
2 citations
Subanesthetic ketamine shows rapid neuroplastic and antidepressant effects in psychiatric conditions, prompting interest in its potential relevance for cognitive dysfunction in neurological disorders. Cognitive deficits are widespread across traumatic brain injury, stroke, epilepsy, and neurodegenerative diseases, yet treatments remain primarily compensatory. Ketamine's actions on glutamatergic...
Frontiers in Neurology
December 9, 2025
Xiaoli Ji, Haiyan Ding, Yingtao Meng
3 citations
Background Postoperative cognitive dysfunction and psychological problems seriously affect the quality of life and recovery of lung cancer patients. As an emerging psychological intervention method, mindfulness-based stress reduction (MBSR) has been widely recognized and applied in the medical field. Objectives Evaluating the effectiveness of MBSR as an intervention for postoperative cognitive...
Frontiers in Neurology
June 25, 2025
Rania Abutarboush, Usmah Kawoos, Rita de Gasperi et al.
3 citations
Introduction Many Veterans who experienced blast-related traumatic brain injuries (TBIs) in Iraq and Afghanistan currently suffer from chronic cognitive and mental health problems that include depression and post-traumatic stress disorder (PTSD). Male rats exposed to repetitive low-level blast develop chronic cognitive and PTSD-related behavioral traits that are present for more than 1 year...
Frontiers in Neurology
2025
Martina Cacciatore, Francesca Giulia Magnani, Filippo Barbadoro et al.
11 citations
Consciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. Within this framework, the thalamus represents a relay station enabling the transmission, reception, and integration of information. However, it is divided into several nuclear groups each composed of functionally heterogeneous nuclei, and, to date, an agreement on which nuclei are most...
Frontiers in Neurology
2025
Chunyan Zhao, Meijiao Zhang, Qingping Zhang et al.
2 citations
This study aimed at summarizing the clinical and neuroimaging features of patients with claustrum sign, so as to enhance the understanding of this imaging feature and explore its clinical significance. Clinical data from 20 patients with claustrum sign were collected. The clinical characteristics, neuroimaging evolution, and outcomes were analyzed. This cohort included 14 males and 6 females...
Frontiers in Neurology
2025
Tan Zhang, Nan Wang, Xiaoke Chai et al.
2 citations
This study aimed to investigate the brain's hemodynamic responses (HRO) and functional connectivity in patients with disorders of consciousness (DoC) in response to acute pressure pain stimulation using near-infrared spectroscopy (NIRS). Patients diagnosed with DoC underwent pressure stimulation while brain activity was measured using NIRS. Changes in oxygenated hemoglobin (HbO) and...
Frontiers in Neurology
2025
Sui H Wong, Janet Wingrove
1 citation
Visual snow syndrome (VSS) is a neurological disorder characterized by intrusive visual symptoms and associated with dysregulation in brain networks, including the Salience Network, Default Mode Network, and thalamocortical circuits. This perspective paper examines the application of mindfulness-based cognitive therapy modified for visual symptoms (MBCT-vision) as an intervention for VSS....
Frontiers in Neurology
2025
Wenjia He, Xinyu Lyu, Hui Zhang et al.
To compare the characteristics of resting-state functional connectivity (FC) before and after repositioning therapy in patients with benign paroxysmal positional vertigo (BPPV) using functional near-infrared spectroscopy (fNIRS). Fifty BPPV patients and fifty healthy controls were enrolled. Oxygenated hemoglobin (HbO) concentration changes during resting-state were recorded using fNIRS. The...
Frontiers in Neurology
2025
Xiaofei Pang, Dong Qiu, Xiaowen He et al.
To explore the therapeutic effect of mindfulness-based stress reduction in patients with post-stroke mild depression. A total of 80 patients with mild depression after stroke received by our hospital from January 2023 to December 2023 were selected as the study subjects. Randomly divide the patients into two groups: 40 in the control group and 40 in the combination group. The control group...
Frontiers in Neurology
2024
Wolfram Strupp
5 citations
There are various electromagnetic (EM) field theories of consciousness. They postulate an epineural EM field which, due to its binding properties, unifies the different neuronal information differences originating from various sensory and cognitive processes. Only through a real physical integration in space within this field could phenomenal consciousness arise. This would solve the binding...
Frontiers in Neurology
June 29, 2023
Benjamin N. Blond, Emmanuelle A. D. Schindler
11 citations
Classic psychedelics are currently re-emerging as therapeutic agents with unique clinical benefits; however, it is also important to recognize the adverse effects of this drug class. While the risk of seizures with this drug class is known, the literature is lacking in detail. We present a case of psychedelic mushroom-induced seizures in a person with refractory right temporal lobe epilepsy...
Frontiers in Neurology
2023
Melisa A Gantt
5 citations
Given that the stages of sleep have specific brainwave patterns, it may be feasible to manipulate brainwaves to induce stages of sleep to improve better sleep quality. Binaural beat frequencies (BBFs) are an auditory-neurologic technique that uses auditory tones via headphones to manipulate brainwave activity in turn affecting the listener's state of consciousness. However, BBFs are often sold...
Frontiers in Neurology
May 6, 2022
Hannah Ford, Clare L. Fraser, Emma J. Solly et al.
28 citations
Background Hallucinogen persisting perception disorder (HPPD) is characterized by the re-emergence of perceptual symptoms experienced during acute hallucinogen intoxication following drug cessation. The underlying pathophysiology is poorly understood. We report the clinical characteristics and investigation findings of a series of HPPD cases with a literature review of previous case reports. We...
Frontiers in Neurology
2020
Peter Fazekas, Georgina Nemeth
14 citations
Hobson's AIM theory offers a general framework for thinking about states of consciousness like wakefulness, REM dreaming and NREM mentations in terms of a state space defined by the dimensions of the level of brain activity, the source of input, and the type of neurochemical modulation. This account inspired theoretical models of other altered states of consciousness-including hypnosis-claiming...
Frontiers in Neurology
2020
Baland Jalal, Ludovico Moruzzi, Andrea Zangrandi et al.
13 citations
Sleep paralysis (SP) is a condition where a person is paralyzed upon waking or falling asleep. SP afflicts ~20% of people, and is also one of the typical symptoms in narcolepsy. During SP the sleeper may experience hallucinations. Unsurprisingly, SP is associated with great fear globally. To date, there are no published clinical trials or outcome data for treating this condition. However, few...
Frontiers in Neurology
2020
Benjamin Putois, Wendy Leslie, Claire Asfeld et al.
In order to ensure robust relationships between the dependent and independent variables in clinical dream/nightmare studies, the major factors which influence the frequency of reported dreams must be controlled. This article sets out methodological recommendations to both researchers seeking to ensure the equivalence of experimental groups of participants in group-matching designs, and to...
Frontiers in Neurology
2020
Alain Nicolas, Perrine Ruby
Over the past 60 years, the impact of psychotropic drugs on dream recall and content has been scarcely explored. A review of the few existing experimental results on the topic leads us to the following conclusions. For antidepressant drugs, in the great majority, they reduce dream recall frequency (DRF), and the improvement of depressive symptoms is associated with an increase of positive...
Frontiers in Neurology
September 18, 2019
Yang Wang, Yun Qin, Hui Li et al.
Internet addiction (IA) has become a global mental and social problem, which may lead to a series of psychiatric symptoms including uncontrolled use of internet, and lack of concentration. However, the exact pathophysiology of IA remains unclear. Most of functional connectivity studies were based on pre-selected regions of interest (ROI), which could not provide a comprehensive picture of the...
Frontiers in Neurology
2019
Carla Thür, Marte Roel Lesur, Christopher J Bockisch et al.
12 citations
The bodily self is a fundamental part of human self-consciousness and relies on online multimodal information and prior beliefs about one's own body. While the contribution of the vestibular system in this process remains under-investigated, it has been theorized to be important. The present experiment investigates the influence of conflicting gravity-related visual and bodily information on...
Frontiers in Neurology
2019
Maaike M Rademaker, Inge Stegeman, Krysten E Ho-Kang-You et al.
Objectives: With this systematic review we aim to provide an overview of the evidence of the effect of Mindfulness Based Interventions (MBIs) on (1) tinnitus distress and (2) anxiety and/or depression in tinnitus patients. Methods: We conducted a systematic search in PubMed Medline, EMBASE and PsycInfo combining the terms and synonyms of "Tinnitus" and "Mindfulness." The most recent search was...
Frontiers in Neurology
2019
Serena Scarpelli, Aurora D'Atri, Chiara Bartolacci et al.
Several findings underlined that the electrophysiological (EEG) background of the last segment of sleep before awakenings may predict the presence/absence of dream recall (DR) in young subjects. However, little is known about the EEG correlates of DR in elderly people. Only an investigation found differences between recall and non-recall conditions during NREM sleep EEG in older adults,...
Frontiers in Neurology
2019
Ahmed S BaHammam, Aljohara S Almeneessier
Obstructive sleep apnea (OSA) can present with or provoke various psychological symptoms. In this article, we critically review studies that have examined dreams, dream recall, and dream content in patients with OSA. Obstructive events induce recurrent sleep fragmentation and intermittent desaturations in patients with OSA, which may trigger different parasomnias, including nightmares....