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Frontiers in Aging Neuroscience

ISSN 1663-4365

7 papers in the library · 38 citations · publishing 2016-2025

Papers

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Ketamine does not rescue plaque load or gap detection in the 5XFAD mouse model of Alzheimer's disease.

Frontiers in Aging Neuroscience 2025 Alexa L Wright, Aldis P Weible, Olivia B Estes et al. 1 citation

Ketamine has received growing attention for its effects on neuroplasticity and neuroinflammation, and as a treatment for depression and other mental health disorders. Recent evidence suggests that early sensory and behavioral deficits in Alzheimer's disease could be caused by synaptic disruption that occurs before irreversible neuropathology. This raises the possibility that ketamine could slow...

Eliciting brain waves of people with cognitive impairment during meditation exercises using portable electroencephalography in a smart-home environment: a pilot study

Frontiers in Aging Neuroscience May 30, 2023 Ioulietta Lazarou, V. Oikonomou, Lampros Mpaltadoros et al.

Objectives Meditation imparts relaxation and constitutes an important non-pharmacological intervention for people with cognitive impairment. Moreover, EEG has been widely used as a tool for detecting brain changes even at the early stages of Alzheimer’s Disease (AD). The current study investigates the effect of meditation practices on the human brain across the AD spectrum by using a novel...

Three potential neurovascular pathways driving the benefits of mindfulness meditation for older adults.

Frontiers in Aging Neuroscience 2023 Jessica Pommy, Colette M Smart, Andrew M Bryant et al.

Mindfulness meditation has been shown to be beneficial for a range of different health conditions, impacts brain function and structure relatively quickly, and has shown promise with aging samples. Functional magnetic resonance imaging metrics provide insight into neurovascular health which plays a key role in both normal and pathological aging processes. Experimental mindfulness meditation...

Mindfulness-based cognitive therapy vs. a health enhancement program for the treatment of late-life depression: Study protocol for a multi-site randomized controlled trial.

Frontiers in Aging Neuroscience 2022 Magnus Bein, Myriam Lesage, Elena Dikaios et al.

Late-life depression (LLD) affects up to 18% of older adults and has been linked to elevated dementia risk. Mindfulness-based cognitive therapy (MBCT) holds promise for treating symptoms of depression and ameliorating cognitive deficits in older adults. While preliminary findings are promising, a definitive RCT investigating its effects on late life depression and cognition have not yet been...

Enhanced Interplay of Neuronal Coherence and Coupling in the Dying Human Brain.

Frontiers in Aging Neuroscience 2022 Raul Vicente, Michael Rizzuto, Can Sarica et al.

The neurophysiological footprint of brain activity after cardiac arrest and during near-death experience (NDE) is not well understood. Although a hypoactive state of brain activity has been assumed, experimental animal studies have shown increased activity after cardiac arrest, particularly in the gamma-band, resulting from hypercapnia prior to and cessation of cerebral blood flow after cardiac...

Greater Anteroposterior Default Mode Network Functional Connectivity in Long-Term Elderly Yoga Practitioners

Frontiers in Aging Neuroscience July 2, 2019 Danilo Forghieri Santaella, Joana Bisol Balardin, Rui F. Afonso et al. 37 citations

Large-scale brain networks exhibit changes in functional connectivity during the aging process. Recent literature data suggests that Yoga and other contemplative practices may revert, at least in part, some of the aging effects in brain functional connectivity, including of the Default Mode Network (DMN). The aim of this cross-sectional investigation was to compare resting-state functional...

Effects of long-term mindfulness meditation on brain's white matter microstructure and its aging.

Frontiers in Aging Neuroscience January 15, 2016 Davide eLaneri, Verena eSchuster, Bruno eDietsche et al.

Although research on the effects of mindfulness meditation (MM) is increasing, still very little has been done to address its influence on the white matter (WM) of the brain. We hypothesized that the practice of MM might affect the WM microstructure adjacent to five brain regions of interest associated with mindfulness. Diffusion tensor imaging was employed on samples of meditators and...