Neuroimage
December 15, 2025
Qingyan Kong, Yue Wang, Min Li et al.
Flow is a deeply immersive state that supports optimal performance, yet its neural basis under conditions of real-world expertise remains poorly understood. Using functional MRI, this study investigated how long-term Chinese calligraphy expertise relates to flow in a culturally meaningful setting. Expert and novice participants performed imagined embodied handwriting of Kai-Shu and Cao-Shu,...
Pharmacology, biochemistry, and behavior
December 1, 2024
Lifen Liu, Rui Li, Lanxia Wu et al.
3 citations
Patients diagnosed with post-traumatic stress disorder (PTSD) mainly exhibit enduring adverse emotions, heightening susceptibility to suicidal thoughts and behaviors. Notably, metabolites of ketamine, particularly (2R,6R)-hydroxyketamine (HNK), have demonstrated favorable antidepressant properties. However, the precise mechanism through which HNK exerts its therapeutic effects on negative...
BMJ Open
September 25, 2024
Yi Long, Donghuang Hong, Haibin Ni et al.
1 citation
Pain is common in patients receiving mechanical ventilation in the intensive care unit (ICU). Intravenous opioids are recommended as first-line therapy for pain management; however, opioids have adverse side effects. Based on low-quality evidence, low-dose ketamine is therefore recommended as an opioid adjunct to reduce opioid consumption. Esketamine is an alternative to ketamine with greater...
bioRxiv (Cold Spring Harbor Laboratory)
October 16, 2023
Xiaofei Jia, Rui Li, Changle Zhou
preprint
Abstract Leyi mental training comprises physical and mental cultivation methods, such as relaxation, breathing, meditation, koan, and cognitive regulation, with the ultimate goal of achieving enlightenment. Over a decade of practical experience has demonstrated its potential to enhance individuals’ mental well-being. In our study, we employed EEG and psychological scales to investigate the...
Frontiers in Cellular Neuroscience
February 15, 2023
Cui-Hong Zhou, Xinxin Zhao, Xinxu Ma et al.
Introduction: Compelling evidence indicates that a single sub-anesthetic dose of (S)-ketamine elicits rapid and robust antidepressant effects. However, the underlying mechanisms behind the antidepressant effects of (S)-ketamine remain unclear. Methods: Here, using a chronic variable stress (CVS) model in mice, we analyzed changes inthe lipid compositions of the hippocampus and prefrontal cortex...