We take a wide view across the emerging research into psychedelics and psychosis/madness, to emphasize the need for not just more but also wise research at these intersections. We note the growing rate of publications on the use of psychedelics by people who have had experiences of psychosis/madness, and make our arguments around a narrative report of the lead author, who experienced a...
We report a clinical case illustrating rapid, reversible, and reproducible hemispheric differences in subjective experience and autonomic arousal during lateral visual field viewing. A man in his 40s with longstanding anxiety and depression showed repeatable shifts in affective state, self-appraisal, and appraisal of the clinician when alternately viewing through the right versus left lateral...
Background:The global burden of psychological disorders, ranging from neuroses to severe psychoses, necessitates comprehensive treatment modalities that extend beyond pharmacotherapy.While conventional psychiatry addresses neurochemical imbalances, there is a growing recognition of the need for "Neuro-psycho-social" interventions that address the structural connectivity of the brain...
Based on Indian traditions, Vibrational healing activities, especially Indian classical music and mantra therapy, have continued to attract growing interest for their ability to promote psychological wellness. As the problem of stress, anxiety, and emotional upsets becomes more widespread, the demand for complementary and culturally-oriented mental health care increases. The current review...
Background: Racially and ethnically minoritized individuals (REMs) who experience discrimination are at risk of developing stress, anxiety, and depression, and digital mental health interventions (DMHIs) can make evidence-based treatments such as mindfulness available to these groups. However, REMs are significantly underrepresented in the overall DMHI and mindfulness-based DMHI literature,...
PsyArXivMay 14, 2026Jacob Cohen, Peter Parbo, Per Trads Ørskov et al.
preprint
Background: Social anxiety disorder is a chronic and disabling condition with limited response to standard therapies. Low-dose psilocybin may enhance the effectiveness of exposure-based treatments by modulating neural circuits associated with fear and avoidance. Virtual reality exposure therapy offers a controlled and individualized platform for intervention. Objective: This phase 2b,...
In india, the birthplace of contemplative traditions, mindfulness has evolved from its ancient roots in sanatan philosophy and the indian knowledge system (iks) into a diverse spectrum of practices ranging from spiritual sadhana (discipline) to secular clinical interventions. This study examines the factors contributing to this transformation, focusing on individuals practicing meditation...
Background: Treatment-resistant depression (TRD) affects a significant proportion of individuals with major depressive disorder and remains difficult to manage with conventional treatments. Psychedelic-assisted therapies and neuromodulation have emerged as innovative interventions targeting neurobiological mechanisms beyond traditional antidepressant approaches. Objectives: This scoping review...
This study addresses Foreign Language Anxiety (FLA), a common issue in language learning, particularly in Arabic instruction at Madrasah Aliyah Raudlatut Tholabah Banyuwangi, where students often experience anxiety and fear of making mistakes while speaking Arabic. The purpose of this study is to explore the use of mindfulness techniques to reduce FLA and enhance language learning. Using a...
Provided herein are novel tricyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse and headaches, and processes for preparing such compounds.
Stressful working conditions continue to impact teacher shortages in special education. Although systemic changes are necessary to improve special educators’ experiences in schools, offering explicit instruction on stress-reducing strategies in special education teacher preparation programs may support special educators’ flourishing/comprehensive well-being and reduce burnout, thereby reducing...
Although Islamic psychotherapy has received attention in various previous studies, research that specifically discusses the structured procedures and clinical mechanisms of Islamic psychotherapy techniques for treating anxiety and stress in Muslim populations remains limited. This study aims to analyze and evaluate the main procedures of Islamic psychotherapy in treating anxiety and stress...
The contemporary world is increasingly characterized by psychological instability, emotional fragmentation, existential uncertainty, and spiritual alienation. In the midst of technological advancement and material progress, modern humanity continues to suffer from anxiety, depression, restlessness, and a persistent crisis of meaning. Ancient Indian philosophical traditions, particularly the...
AIM This updated systematic review and meta-analysis aimed to evaluate the effectiveness of mindfulness-based interventions (MBIs) in reducing stress, anxiety, depression and improving mindfulness among nursing students. BACKGROUND Nursing students often experience significant psychological distress due to the demanding academic and clinical environments of nursing education. MBIs have been...
MindfulnessMay 1, 2026Cláudia P. Pires, Julieta Azevedo, Raquel Guiomar et al.
Abstract Objectives Research on structured, manualized psychotherapeutic interventions for high test anxiety (TA) in adolescents remains limited, particularly those integrating acceptance, mindfulness, and compassion-based strategies. These psychological processes have been identified as protective factors for test anxiety, fostering adaptive emotional regulation and resilience. The AcAdeMiC...
The aim of this study is to examine the effect of mindfulness-based stress reduction intervention on educational stress and coping with exam anxiety and mindfulness in nursing students. This study utilizes a quasi-experimental design with the pretest-post-test control group. Personal information form, nursing education stress scale (NESS), state test anxiety scale (STAS), and mindful attention...
Brain and BehaviorMay 1, 2026Mauro Cozzolino, Marco Borgese, Giovanna Celia
BACKGROUND: University students face increasing levels of stress, anxiety, and self-efficacy, which may disrupt autonomic balance. While many mind-body interventions require sustained practice, growing evidence suggests that even a single session can yield immediate benefits. This randomized controlled trial compared the immediate and short-term effects of the brain wave modulation technique...
CureusMay 1, 2026Anupinder Thind, Pravin M Pisudde, Sonia Kochhar
Medical education has long been acknowledged as a very stressful career path that exposes students to greater chances of anxiety and burnout. The purpose of this systematic review and meta-analysis was to determine the overall impact of yoga-based volitional breathing (pranayama) interventions on self-perceived stress and anxiety among medical students worldwide. The review analysis was...
This study used a daily diary method to examine the temporal relationship between distress tolerance (DT), anxiety, and depression during a mindfulness-based intervention (MBI). A total of 83 participants with high emotional distress completed daily diaries of mindfulness, DT, anxiety and depression over one week before, during, and after the intervention. Linear mixed models showed significant...
SleepMay 1, 2026Holland Doise, A. Gonzalez Quesada, Garrett Baber et al.
Abstract Introduction Nightmares are associated with more severe posttraumatic stress disorder (PTSD). The advent of large language models (LLM) offers unique advantages to efficiently code affective dream content over human methods, which can be resource intensive and prone to error. This study tested whether dream affect (DA), measured via self-report, human-rated narrative coding, and LLM...