Mindfulness meditation (MM) is a promising cognitive strategy that may facilitate motor learning by improving attention and reducing anxiety. Our study aimed to investigate the effects of guided MM on motor learning in healthy young adults. The study was conducted as randomised controlled trials where 24 meditation-naive participants underwent either a 10-min MM session or seated rest (CT)...
Rajayoga meditation is form of meditation that is offered by Rajayoga Education and Research Foundation of Brahma Kumaris World Spiritual University. It is free of ritual and mantras and can be performed anywhere and anytime. The Rajayoga meditation practice can have beneficial effects on modulating anxiety and cortisol levels in breast cancer patients undergoing surgery. To evaluate the impact...
The purpose of this study was to conduct a scoping review to map the existing literature on the use of mantra meditation in sport contexts, clarify its conceptual distinctions from related constructs such as self-talk, and identify directions for future research. This study employed a comprehensive literature search, combining electronic database searches (including Web of Science, Psychology &...
Depersonalization (DP) and Derealization (DR) refer to perceptual changes of "as-if-character" where the self (→DP) or the surroundings (→DR) are experienced as unreal. These symptoms are highly prevalent in individuals with mental disorders. If these symptoms persist most of the day for months, the diagnosis of depersonalization-derealization-disorder (DDD) is likely. DDD is a common disorder...
Nightmare Disorder characterized by recurrent dysphoric dreams is strongly associated with major depressive episodes (MDE) and suicidal risk. Imagery rehearsal therapy (IRT) is the standard treatment for nightmares, but its effectiveness in individuals with MDE remain understudied. This study evaluated whether IRT is associated with greater improvement in nightmare symptoms compared to sleep...
Surgical stress can lead to postoperative anxiety and depression, especially in adolescents. These complications reduce quality of life and increase medical burdens, but perioperative psychological interventions for adolescents are limited, and related mechanisms remain unclear. Esketamine (S-ketamine), an N-methyl-D-aspartate receptor (NMDAR) antagonist, has analgesic, sedative,...
Background We aimed to evaluate the effects of yoga and guided meditation on stress, anxiety, and well-being in emergency medicine residents. Methods We randomly assigned 81 participants to yoga, guided meditation, or control using a single-level block randomization design. The yoga group attended Hatha yoga classes twice a week, the meditation group learned the technique with audio recordings...
Death anxiety is prevalent across many modern cultures and is associated with significant psychological, social and economic costs, including avoidance of advance care planning and the overuse of life-prolonging medical interventions at the end of life. From a yogic perspective, this pervasive clinging to life reflects abhinivesha, one of the five kleshas (mental afflictions) described as a...
Some individuals interpret persistent depression and anxiety, alongside the exhaustion of standard treatment options, as leading to a desperate need for relief. While desperation may shape how people assess treatment options, its role in psychedelic self-treatment and its relevance for emerging clinical models of psychedelic treatment remain underexplored. We collected discussion threads from...
Neurofeedback (NF) has been proposed as a tool to support and expand access to meditation practice. Despite growing interest, no comprehensive review has examined neurofeedback for meditation-based interventions (NF-MED) across the full spectrum of practices. Here, we conducted a scoping systematic review according to PRISMA guidelines, mapping the NF-MED field across both clinical and...
Ketamine is a dissociative anesthetic with potential for treating mood, anxiety, and related disorders; however, concerns have emerged regarding hepatotoxicity in the context of chronic treatment. Systematic searches of PubMed, Scopus, and Ovid databases were conducted from inception to August 2025. Eligible studies included randomized controlled trials (RCTs), observational studies, and case...
Frontiers in Psychiatry2026Gláucio Silva Camargos, Geraldo Magela De Faria Júnior, Marcelo Lourenço et al.
This longitudinal observational study evaluated changes in depressive symptoms associated with ritualistic ayahuasca use in patients diagnosed with depressive disorders, as well as depressive burden in individuals with anxiety and substance use disorders. The research was conducted with 280 adults treated at clinics in the northwestern region of the state of São Paulo, under the jurisdiction of...
BACKGROUND: While clinical research on psychedelics often reports mild and transient side effects, broader survey studies indicate that a subset of users experiences lasting adverse mental health effects. This study investigated whether some of these meet diagnostic criteria for post-traumatic stress disorder (PTSD). METHODS: = 243) was conducted with individuals reporting distressing...
Party drugs encompass a broad spectrum of legal and illegal psychoactive substances used in party settings such as clubs, festivals, raves or private gatherings to modulate mood, perception, social interaction and bodily states. Most commonly, alcohol and cannabis are consumed, followed by amphetamine, MDMA (“ecstasy”), cocaine and ketamine. Synthetic cathinones, GHB/GBL (“liquid ecstasy”),...
Self-compassion is theorized to play a central role in promoting mental health and wellbeing, including for individuals with social anxiety disorder (SAD). One proposed mechanism of MDMA-assisted therapy (MDMA-AT) for SAD is the cultivation of self-compassion. Across five aims, we will characterize self-compassion experiences during MDMA-AT and evaluate its role as a potential mechanism of...
Hallucinogen Persisting Perception Disorder (HPPD) is a condition affecting 1-5% of psychedelic users, with higher prevalence observed among recurrentLSD consumers and synthetic cannabinoid users [1]. The disorder is characterised by persistent visual disturbances including palinopsia and visual snow, along with dissociative symptoms, which have been neurobiologically linked to 5-HT2A receptor...
PLoS One2026Yijun Wang, Xiaolu Lin, Xiang Zou et al.
Postoperative pain is the most notable issue after cesarean section (CS). The contributing factors include hyperalgesia, anxiety, depression, sleep disorders, and inflammation. In this study, we explored the effects of esketamine on pain, hyperalgesia, depression, anxiety, sleep disorders, and inflammation after CS. This randomized, blinded, controlled trial enrolled single-term pregnant women...
ABSTRACT Objective Anxiety is common in patients receiving end‐of‐life care and significantly impacts their quality of life. However, pharmacological management remains challenging due to complex clinical presentations and potential side effects, emphasizing the need for systematically reviewing existing treatments. Here we aim to systematically evaluate the efficacy and safety of...
Abstract Binge Eating Disorder (BED) is the most prevalent eating disorder and is associated with psychiatric comorbidities, health impairments, and decreased quality of life. Emerging evidence suggests that psilocybin-assisted therapy may promote cognitive and emotional flexibility and disrupt maladaptive behavioral patterns, making it a promising candidate for BED treatment. This open-label...