ACS Medicinal Chemistry Letters
August 13, 2026
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel tetrahydropyridinyl-6,6-bicyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse and headaches, and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
July 3, 2026
Ram W. Sabnis, Anika R. Sabnis
High Resolution Image Download MS PowerPoint Slide Provided herein are novel 6,5-bicyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse, and headaches, and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
June 3, 2026
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel 5,6-bicyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse and headaches, and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
May 7, 2026
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel tricyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse and headaches, and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
April 27, 2026
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel indoline derivatives serotonergic psychedelic agents as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
March 13, 2025
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel compounds as 5-HT2A receptor modulators, pharmaceutical compositions, use of such compounds in treating psychiatric and neurological disorders and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
February 13, 2025
Ram W. Sabnis, Anika R. Sabnis
High Resolution Image Download MS PowerPoint Slide Provided herein are novel tryptamine compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mood disorders such as depressive disorders and bipolar disorders and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
February 11, 2025
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mental illness or CNS disorders and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
January 23, 2025
Ram W. Sabnis, Anika R. Sabnis
3 citations
Provided herein are novel indoline derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.
ACS Medicinal Chemistry Letters
January 23, 2025
Ram W. Sabnis, Anika R. Sabnis
Provided herein are novel pyrrolopyridine compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mental illnesses, and processes for preparing such compounds.