Background: Psychedelics, including classic psychedelics, 3,4-methylenedioxymethamphetamine (MDMA), and ketamine, are increasingly investigated for psychiatric disorders, but their effects on sleep remain unclear. Objectives: To systematically evaluate the effects of these interventions on subjective and objective sleep outcomes and summarize sleep-related adverse events. Design: A systematic...
Introduction Psilocybin is a classic psychedelics, which has been shown to have antidepressant effects by many studies in recent years. In this study, we aim to evaluate the efficacy, acceptability and tolerability of psilocybin in the treatment of primary (major depressive disorder) or secondary (experiencing distress related to life-threatening diagnoses and terminal illness) depression....