Abstract: Objectives: Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes, with neuropathic pain and sensory abnormalities severely affecting patients’ quality of life. Current pharmacological treatments have limitations including insufficient efficacy and adverse reactions. Mindfulness-based interventions (MBIs) show potential in chronic pain management, yet their...
Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. It has a slow and insidious onset, mainly manifested as sensory and motor dysfunction, and increases susceptibility to psychological problems such as anxiety and depression, seriously affecting the quality of life of patients. The current treatment strategies focus on effective metabolic management...
Mindfulness-based cognitive therapy (MBCT) has been documented to be effective in treating obsessive-compulsive disorder (OCD). However, the neurobiological basis of MBCT remains largely elusive, which makes it clinically challenging to predict which patients are more likely to respond poorly. Hence, identifying biomarkers for predicting treatment outcomes holds both scientific and clinical...
Background: This was the first randomized controlled trial (RCT) designed to compare the efficacy of mindfulness-based cognitive therapy (MBCT) on unmedicated obsessive-compulsive disorder with that of the first-line treatment for OCD (SSRIs) or a placebo, as well as to analyze the treatment acceptability and safety of MBCT. Methods: A total of 123 unmedicated OCD patients with mild to moderate...
Background: In this report, a study protocol for a randomized control trial is presented in an attempt to explore the efficacy of mindfulness-based cognitive therapy (MBCT) for major depressive disorder (MMD), and a case-control study is conducted to find the difference in electroencephalograms (EEGs) between MMD and normal controls. Design: Seventy Chinese patients with MMD will be chosen for...
This article presents a study protocol for a single-blind randomized controlled trial to test the efficacy and feasibility of mindfulness-based cognitive therapy. A total of 120 un-medicated Chinese obsessive-compulsive disorder patients will be randomized to the mindfulness-based cognitive therapy group, the selective serotonin reuptake inhibitor group or the psycho-education group for 11...