INTRODUCTION: This study investigated changes in multiband amplitude of low-frequency fluctuations in patients with major depressive disorder following a 2-week combination treatment regimen of esketamine and sertraline, and examined the associations between ALFF changes and clinical symptom improvement. METHODS: Forty patients with major depressive disorder (MDD) received esketamine (0.25...
The association between near-death experiences (NDEs) and physiological indicators remains an unsolved mystery, which hinders in-depth understanding of the essence of consciousness and life processes. Traditional single-indicator analysis methods have limitations, and a comprehensive multi-modal research approach is urgently needed to advance relevant explorations in the fields of medicine,...
Family system factors have been consistently linked to children's prosocial behavior. However, the mechanisms underlying these associations remain unclear. Drawing on family system theory, attachment theory, and social learning theory, the present study examined the associations between parental mindfulness and preschoolers' prosocial behavior, as well as the mediating roles of marital quality...
Abstract Background Nonsuicidal self-injury (NSSI) in adolescents with depressive disorder is characterized by recurrent impulsivity and is a predictor of future suicidal behavior, necessitating effective and feasible interventions. Mindfulness-based cognitive therapy for adolescents (MBCT-A), a first-line treatment for depression, was evaluated in this trial for its efficacy in reducing NSSI...
Postoperative acute pain is a common issue in children after surgery. Our study aimed to investigate whether preoperative use of a dexmedetomidine-esketamine combination could reduce postoperative pain in children undergoing tonsillectomy and adenoidectomy and reduce side effects, such as bradycardia, hypotension or emergence delirium. In this double-blind, randomised controlled clinical trial,...
Abstract Background Demoralization, a significant mental health concern in patients with chronic diseases, can have a large impact on physical symptom burden and quality of life. The present review aimed to evaluate the effectiveness of interventions for demoralization among patients with chronic diseases. Method PubMed, Scopus, Embase, and Web of Science were systematically searched. Research...
Increasing interest in hypnotherapy's application for a wide range of health conditions has spurred a rise in global research and publications. This study aims to visualize development patterns and current research hotspots in clinical hypnotherapy practice using scientometric methods, and to predict future research directions based on the keyword trending topics analysis. Data on hypnotherapy...
Background: The incidence rate of depression in youth demographic increases year by year. High-level psychological capital is conducive to relieving depression, and mindfulness training is an effective psychotherapy. We aimed to investigate the influences of mindfulness training on psychological capital, depression, and procrastination, thereby providing a direction for psychotherapy in the...