Sleep
May 1, 2025
Maria José Pereira Morais, A. Bezerra, C. Banzoli et al.
An epidemiological study conducted by the Sleep Institute in 2007 revealed that 44.8% of the population in São Paulo exhibited symptoms of insomnia, with women being disproportionately affected (32%). Considering a global adaptation towards utilizing technology for health services, the present study evaluated the effects of an online meditation program on women with insomnia. The study was a...
Sleep Science
December 1, 2023
Julia Ribeiro Da Silva Vallim, Gabriela Sant'Ana Lima, Gabriel Natan Pires et al.
Introduction Systematic reviews and metanalyses have shown that mindfulness-based interventions can have positive effects on health, such as reducing anxiety, depression, and chronic pain. However, their effect on sleep-related outcomes is not yet well established. Sleep can be assessed subjectively (questionnaires, sleep logs, self-reporting) and/or objectively (actigraphy, polysomnography,...
Menopause: The Journal of The North American Menopause Society
September 2018
Marcelo C Garcia, Elisa H. Kozasa, Sergio Tufik et al.
The aim of the study was to evaluate the effects of mindfulness and relaxation training for insomnia on insomnia and quality of life in postmenopausal women. Thirty postmenopausal women aged 50 to 65 years, who were not using hormone therapy, and had a diagnosis of insomnia and an apnea-hypopnea index of less than 15, were randomly assigned to two groups: a mindfulness intervention group and a...
Journal of Clinical Sleep Medicine
December 15, 2015
Lenise Jihe Kim, Fernando Morgadinho Coelho, Camila Hirotsu et al.
Objectives: Narcolepsy is a disabling disease with a delayed diagnosis. At least 3 years before the disorder identification, several comorbidities can be observed in patients with narcolepsy. The early recognition of narcolepsy symptoms may improve long-term prognosis of the patients. Thus, we aimed to investigate the prevalence of the symptoms associated with narcolepsy and its social and...
Behavioural Processes
September 22, 2014
Tathiana A. Alvarenga, Daniel Ninello Polesel, Gabriela Matos et al.
10 citations
The ingestion of the beverage Ayahuasca usually occurs in religious ceremonies that are performed during the night leading to sleep deprivation. The purpose of the present study was to characterize the acute effects of Ayahuasca upon the sexual response of sleep deprived male rats. One group of sexually experienced male Wistar rats were submitted to a paradoxical sleep deprivation (PSD)...
Biochemical Pharmacology
April 1, 2014
Melissa M. Gomes, J. B. Coimbra, R. O. Clara et al.
21 citations
Tryptophan (TRP) is essential for many physiological processes, and its metabolism changes in some diseases such as infection and cancer. The most studied aspects of TRP metabolism are the kynurenine and serotonin pathways. A minor metabolic route, tryptamine and N,N-dimethyltryptamine (DMT) biosynthesis, has received far less attention, probably because of the very low amounts of these...
Drug and Alcohol Dependence
November 1, 2011
Roberta Procópio-Souza, Daniela F Fukushiro, Thaís F Trombin et al.
Behavioral sensitization in rodents is hypothesized to reflect neuronal adaptations that are related to drug addiction in humans. We evaluated the effects of group exposure on the acute hyperlocomotion and behavioral sensitization induced by four drugs of abuse in C57BL/6 mice: methylenedioxymethamphetamine (MDMA), d-amphetamine, morphine and ethanol. In the priming session, animals received an...
Addiction Biology
January 2010
Tathiana A. Alvarenga, Mônica L. Andersen, Daniel A Ribeiro et al.
We evaluated the overall genetic damage induced by different doses of cocaine and MDMA (3,4-Methylenedioxymethamphetamine) in several organs. One hour after intraperitoneal drug administration, mice were euthanized; peripheral blood, liver and brain were collected, and the cellular suspensions were used for the single cell gel (comet) assay. We determined that all doses of cocaine and MDMA...